UMMS Affiliation

Department of Medicine, Division of Cardiovascular Medicine

Publication Date

2015-08-28

Document Type

Article

Disciplines

Biological Factors | Cell Biology | Genetics | Molecular Genetics

Abstract

Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.

Keywords

ERCC, biomarkers, exRNA, extracellular RNA

Rights and Permissions

Copyright: © 2015 Joseph F. Quinn et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI of Published Version

10.3402/jev.v4.27495

Source

J Extracell Vesicles. 2015 Aug 28;4:27495. doi: 10.3402/jev.v4.27495. eCollection 2015. Link to article on publisher's website

Journal/Book/Conference Title

Journal of extracellular vesicles

Comments

Full author list omitted for brevity. For the full list of authors, see article.

Related Resources

Link to Article in PubMed

PubMed ID

26320940

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.