Department of Medicine, Division of Cardiovascular Medicine
Biological Factors | Cell Biology | Genetics | Molecular Genetics
Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.
ERCC, biomarkers, exRNA, extracellular RNA
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Copyright: © 2015 Joseph F. Quinn et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOI of Published Version
J Extracell Vesicles. 2015 Aug 28;4:27495. doi: 10.3402/jev.v4.27495. eCollection 2015. Link to article on publisher's website
Journal of extracellular vesicles
Quinn JF, Patel T, Wong D, Das S, Freedman J, Laurent LC, Carter BS, Hochberg F, Saugstad JA. (2015). Extracellular RNAs: development as biomarkers of human disease. Open Access Articles. https://doi.org/10.3402/jev.v4.27495. Retrieved from https://escholarship.umassmed.edu/oapubs/2634
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License