Making enhancers from spare parts of the genome
Program in Bioinformatics and Integrative Biology
Animals; Biological Evolution; Conserved Sequence; *Enhancer Elements, Genetic; Exons; Gene Duplication; *Genes, Developmental; *Genes, Regulator; *Genome; Humans; Mice; Sharks; Smegmamorpha
Genetics and Genomics | Life Sciences | Medicine and Health Sciences
New studies show that novel long-range enhancers of developmental genes can emerge by exaptation of protein-coding sequences with no previous regulatory function.
DOI of Published Version
Genome Biol. 2011 Dec 29;12(12):138. Link to article on publisher's site
Fredman, David; Dong, Xianjun; and Lenhard, Boris, "Making enhancers from spare parts of the genome" (2011). Open Access Articles. 2328.