Title

Hyperinsulinemia-euglycemia therapy: a useful tool in treating calcium channel blocker poisoning

UMMS Affiliation

Department of Emergency Medicine

Publication Date

2006-07-17

Document Type

Article

Subjects

Calcium Channel Blockers; Glucose Clamp Technique; Humans; *Hyperinsulinism; Myocardium

Disciplines

Emergency Medicine | Life Sciences | Medical Toxicology | Medicine and Health Sciences

Abstract

Hyperinsulinemia-euglycemia (HIE) therapy, when initiated promptly and aggressively, may offer considerable advantages in the treatment of calcium channel blocker poisoning. Although its mechanism of action is uncertain, HIE improves the efficiency with which the poisoned myocardium uses metabolic fuel, the end result of which is improvements in inotropy and other cardiovascular parameters. Although HIE is not universally accepted, the reports included in the previous issue of Critical Care should prompt clinicians to consider HIE an appropriate therapy specifically for calcium channel blocker poisoning.

DOI of Published Version

10.1186/cc4964

Source

Crit Care. 2006;10(4):149. Link to article on publisher's site

Journal/Book/Conference Title

Critical care (London, England)

Related Resources

Link to Article in PubMed

PubMed ID

16879723

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