Temporal trends in serum concentrations of polychlorinated dioxins, furans, and PCBs among adult women living in Chapaevsk, Russia: a longitudinal study from 2000 to 2009
Authors
Humblet, OlivierSergeyev, Oleg
Altshul, Larisa
Korrick, Susan A.
Williams, Paige L.
Emond, Claude
Birnbaum, Linda S.
Burns, Jane S.
Lee, Mary M.
Revich, Boris
Shelepchikov, Andrey
Feshin, Denis
Hauser, Russ
Document Type
Journal ArticlePublication Date
2011-06-22Keywords
AdultBenzofurans
Dioxins
*Environmental Exposure
Environmental Pollutants
Female
Gas Chromatography-Mass Spectrometry
Humans
Longitudinal Studies
Polychlorinated Biphenyls
Russia
Young Adult
Cell Biology
Endocrinology, Diabetes, and Metabolism
Environmental Public Health
Life Sciences
Medicine and Health Sciences
Pediatrics
Metadata
Show full item recordAbstract
BACKGROUND: The present study assessed the temporal trend in serum concentrations of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls (PCBs) among residents of a Russian town where levels of these chemicals are elevated due to prior industrial activity. METHODS: Two serum samples were collected from eight adult women (in 2000 and 2009), and analyzed with gas chromatography-high-resolution mass spectrometry. RESULTS: The average total toxic equivalency (TEQ) decreased by 30% (from 36 to 25 pg/g lipid), and the average sum of PCB congeners decreased by 19% (from 291 to 211 ng/g lipid). Total TEQs decreased for seven of the eight women, and the sum of PCBs decreased for six of eight women. During this nine year period, larger decreases in serum TEQs and PCBs were found in women with greater increases in body mass index. CONCLUSIONS: This study provides suggestive evidence that average serum concentrations of dioxins, furans, and PCBs are decreasing over time among residents of this town.Source
Environ Health. 2011 Jun 22;10:62. Link to article on publisher's siteDOI
10.1186/1476-069X-10-62Permanent Link to this Item
http://hdl.handle.net/20.500.14038/39461PubMed ID
21696632; 21696632Related Resources
Link to Article in PubMedRights
© 2011 Humblet et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
ae974a485f413a2113503eed53cd6c53
10.1186/1476-069X-10-62