Department of Psychiatry, Brudnick Neuropsychiatric Research Institute
Animals; Brain Diseases; Chromatin; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Genetic Predisposition to Disease; Histone Deacetylases; Histones; Humans; Nervous System
Life Sciences | Medicine and Health Sciences | Neuroscience and Neurobiology
It is becoming increasingly clear that epigenetic modifications are critical factors in the regulation of gene expression. With regard to the nervous system, epigenetic alterations play a role in a diverse set of processes and have been implicated in a variety of disorders. Gaining a more complete understanding of the essential components and underlying mechanisms involved in epigenetic regulation could lead to novel treatments for a number of neurological and psychiatric conditions.
DOI of Published Version
J Neurosci. 2008 Nov 12;28(46):11753-9. Link to article on publisher's site
The Journal of neuroscience : the official journal of the Society for Neuroscience
Jiang Y, Langley B, Lubin FD, Renthal W, Wood MA, Yasui DH, Kumar A, Nestler EJ, Akbarian S, Beckel-Mitchener AC. (2008). Epigenetics in the nervous system. Open Access Articles. https://doi.org/10.1523/JNEUROSCI.3797-08.2008. Retrieved from https://escholarship.umassmed.edu/oapubs/1955