T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't
UMass Chan Affiliations
Department of Medicine, Division of GastroenterologyDocument Type
Journal ArticlePublication Date
2008-05-23Keywords
AnimalsHepacivirus
Hepatitis C
Humans
Immunity, Cellular
T-Lymphocytes, Regulatory
Viral Core Proteins
Life Sciences
Medicine and Health Sciences
Metadata
Show full item recordAbstract
The mechanism behind the apparent lack of effective antiviral immune response in patients with chronic hepatitis C virus (HCV) infection is poorly understood. Although multiple levels of abnormalities have been identified in innate and adaptive immunity, it remains unclear if any of the subpopulations of T cells with regulatory capacity (Tregs) contribute to the induction and maintenance of HCV persistence. In this review, we summarize the current knowledge about Tregs as they relate to HCV infection.Source
J Leukoc Biol. 2008 Sep;84(3):614-22. Epub 2008 May 21. Link to article on publisher's site
DOI
10.1189/jlb.1107770Permanent Link to this Item
http://hdl.handle.net/20.500.14038/39111PubMed ID
18495782Related Resources
ae974a485f413a2113503eed53cd6c53
10.1189/jlb.1107770