Department of Orthopedics
Animals; Biomedical Engineering; Bone Development; Bone Diseases; Bone Transplantation; Cells, Cultured; Chemical Engineering; Disease Models, Animal; Durapatite; Ethylene Glycol; Graft Survival; Humans; Materials Testing; Osteoblasts; Polymers; Polymethacrylic Acids; Polyurethanes; Prostheses and Implants; Rats; Stress, Mechanical; Stromal Cells; Weight-Bearing
Biotechnology | Life Sciences | Medicine and Health Sciences | Musculoskeletal System | Orthopedics
The design of synthetic bone grafts that possess structural and biochemical microenvironment emulating the extracellular matrix of bone and exhibit good surgical handling characteristics is of significant importance to orthopedic applications. Using a combination of chemical and engineering tools, our lab has developed a number of osteogenic composite bone grafts that possess elastomeric or self-deployable shape memory properties facilitating the repair and regeneration of segmental bony defects.
J Musculoskelet Neuronal Interact. 2007 Oct-Dec;7(4):325. Link to article on publisher's website
Journal of musculoskeletal and neuronal interactions
Song, Jie, "A chemical and engineering approach towards "smart" synthetic bone grafts" (2007). Open Access Articles. 1301.