UMMS Affiliation

Department of Orthopedics

Publication Date

2007-12-21

Document Type

Article

Subjects

Animals; Biomedical Engineering; Bone Development; Bone Diseases; Bone Transplantation; Cells, Cultured; Chemical Engineering; Disease Models, Animal; Durapatite; Ethylene Glycol; Graft Survival; Humans; Materials Testing; Osteoblasts; Polymers; Polymethacrylic Acids; Polyurethanes; Prostheses and Implants; Rats; Stress, Mechanical; Stromal Cells; Weight-Bearing

Disciplines

Biotechnology | Life Sciences | Medicine and Health Sciences | Musculoskeletal System | Orthopedics

Abstract

The design of synthetic bone grafts that possess structural and biochemical microenvironment emulating the extracellular matrix of bone and exhibit good surgical handling characteristics is of significant importance to orthopedic applications. Using a combination of chemical and engineering tools, our lab has developed a number of osteogenic composite bone grafts that possess elastomeric or self-deployable shape memory properties facilitating the repair and regeneration of segmental bony defects.

Source

J Musculoskelet Neuronal Interact. 2007 Oct-Dec;7(4):325. Link to article on publisher's website

Journal/Book/Conference Title

Journal of musculoskeletal and neuronal interactions

Related Resources

Link to Article in PubMed

PubMed ID

18094494

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