Dipyridamole myocardial perfusion imaging

UMMS Affiliation

Department of Radiology, Division of Nuclear Medicine

Publication Date


Document Type



Adenosine; Coronary Disease; Dipyridamole; Heart; Humans; Sensitivity and Specificity; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon


Life Sciences | Medicine and Health Sciences


Dipyridamole is a pharmacologic stressor used in place of exercise for myocardial perfusion imaging in patients who cannot exercise due to various physical limitations. Perfusion studies with dipyridamole can identify coronary artery disease (CAD) as accurately as maximal exercise stress testing. In addition, dipyridamole myocardial perfusion studies are useful to stratify patients according to risk of subsequent cardiac events. As dipyridamole is infused, it blocks the reabsorption and metabolism of adenosine normally produced in the body, producing the desired effect on the heart, coronary hyperemia. Dipyridamole can be used with 201Tl and 99mTc myocardial perfusion tracers, for either planar or SPECT imaging, in patients who cannot exercise or who can only exercise at submaximal levels.


J Nucl Med. 1994 Apr;35(4):730-3.

Journal/Book/Conference Title

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

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Link to Article in PubMed

PubMed ID