Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

Follow


Publications from 2019

File

TRACE-CORE Dataset on Religious Practices and Long-Term Survival after Hospital Discharge for an Acute Coronary Syndrome, Hawa O. Abu, Kate L. Lapane, Molly E. Waring, Christine M. Ulbricht, Randolph S. Devereaux, David D. McManus, Jeroan J. Allison, Catarina I. Kiefe, and Robert J. Goldberg

Link

Transformation Support Provided Remotely to a National Cohort of Optometry Practices, Ronald N. Adler, Warren J. Ferguson, Hussein Antar, Michael Steinkrauss, Brian Bjoern, Valerie Konar, Jay Flanagan, and David F. Polakoff

PDF

Segmental Distribution of Hepatocellular Carcinoma Correlates with Microvascular Invasion in Liver Explants Undergoing Transplantation, Yasir Al-Azzawai, Eva Rouanet, Ryan J. Hendrix, Lidia Spaho, Hesham Malik, Deepika Devuni, Gyongyi Szabo, and Graham Barnard

PDF

Changes in Anticoagulant Utilization Among United States Nursing Home Residents With Atrial Fibrillation From 2011 to 2016, Matthew Alcusky, David D. McManus, Anne L. Hume, Marc Fisher, Jennifer Tjia, and Kate L. Lapane

PDF

Receptor interacting protein kinase 3 (RIP3) regulates iPSCs generation through modulating cell cycle progression genes, Ahmad Al-Moujahed, Bo Tian, Nikolaos E. Efstathiou, Eleni K. Konstantinou, Mien Hoang, Haijiang Lin, Joan W. Miller, and Demetrios G. Vavvas

PDF

Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis, Camila Alvarez-Silva, Robert Schierwagen, Alessandra Pohlmann, Fernando Magdaleno, Frank E. Uschner, Patrick Ryan, Maria J.G.T. Vehreschild, Joan Claria, Eicke Latz, Benjamin Lelouvier, Manimozhiyan Arumugam, and Jonel Trebicka

PDF

Use of Electronic Health Record Access and Audit Logs to Identify Physician Actions Following Noninterruptive Alert Opening: Descriptive Study, Azraa Amroze, Terry S. Field, Hassan Fouayzi, Devi Sundaresan, Laura Burns, Lawrence Garber, Rajani S. Sadasivam, Kathleen M. Mazor, Jerry H. Gurwitz, and Sarah L. Cutrona

PDF

The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans, Sarah M. Anderson, Hilary K. Cheesman, Nicholas D. Peterson, Elisabeth B. Salisbury, Alexander A. Soukas, and Read Pukkila-Worley

PDF

Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia, Sarah R. Anderson, Jianmin Zhang, Michael R. Steele, Cesar O. Romero, Amanda G. Kautzman, Dorothy P. Schafer, and Monica L. Vetter

PDF

Use and Outcomes Associated With Perioperative Amiodarone in Cardiac Surgery, Auras R. Atreya, Aruna Priya, Quinn R. Pack, Penelope S. Pekow, Mihaela Stefan, Tara Lagu, Amir S. Lotfi, and Peter K. Lindenauer

PDF

Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts, Sung-Jin Bae, Min Wook Shin, Taekwon Son, Hye Shin. Lee, Ji Soo Chae, Sejin Jeon, Goo Taeg Oh, and Kyu-Won Kim

PDF

Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018, Jesus M. Banales, Ariel E. Feldstein, Hanna Sanger, Veronika Lukacs-Kornek, Gyongyi Szabo, and Miroslaw Kornek

PDF

Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo, Thiago M. Batista, Ruben Garcia-Martin, Weikang Cai, Masahiro Konishi, Brian T. O'Neill, Masaji Sakaguchi, Jong Hun Kim, Dae Young Jung, Jason K. Kim, and C. Ronald Kahn

PDF

A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection, Lindsey E. Bazzone, Michael King, Christopher R. MacKay, Pyae Phyo Kyawe, Paul Meraner, Daniel Lindstrom, Joselyn Rojas-Quintero, Caroline A. Owen, Jennifer P. Wang, Abraham L. Brass, Evelyn A. Kurt-Jones, and Robert W. Finberg

PDF

A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine, Peter T. Beernink, Vianca Vianzon, Lisa A. Lewis, Gregory R. Moe, and Dan M. Granoff

PDF

Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy, Michelle M. Bellerose, Seung-Hun Baek, Chuan-Chin Huang, Caitlin E. Moss, Eun-Ik Koh, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Jong Seok Lee, Seokyong Eum, Sung Jae Shin, Sang-Nae Cho, Megan Murray, and Christopher M. Sassetti

PDF

The Brazilian private pharmaceutical market after the first ten years of the generics law, Andrea Damaso Bertoldi, Anita K. Wagner, Isabel Emmerick, Luisa Arueira Chaves, Peter Stephens, and Dennis Ross-Degnan

PDF

Using Electronic Referrals to Address Health Disparities and Improve Blood Pressure Control, Amy Bettano, Thomas Land, Alice Byrd, Susan Svencer, and Laura Nasuti

PDF

Intersectional effects of racial and gender discrimination on cardiovascular health vary among black and white women and men in the CARDIA study, Ganga S. Bey, William M. Jesdale, Sarah N. Forrester, Sharina D. Person, and Catarina I. Kiefe

PDF

Still Disease, Juhi Bhargava and Sreelakshmi Panginikkod

PDF

Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions, James R. Birtley, Zachary Maben, Grant C. Weaver, Mollie M. Jurewicz, Lawrence J. Stern, Chiara Recchi, and Hani Gabra

PDF

Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo, Annabelle Biscans, Andrew H. Coles, Reka A. Haraszti, Dimas Echeverria, Matthew R. Hassler, Maire F. Osborn, and Anastasia Khvorova

PDF

Design and methods of the Healthy Kids and Families study: a parent-focused community health worker-delivered childhood obesity prevention intervention, Amy Borg, Christina F. Haughton, Mullen Sawyer, Stephenie C. Lemon, Kevin J. Kane, Lori Pbert, Wenjun Li, and Milagros C. Rosal

PDF

Gait mechanics contribute to exercise induced pain flares in knee osteoarthritis, Katherine A. Boyer and Jocelyn F. Hafer

PDF

Proton pump inhibitors and 180-day mortality in the elderly after Clostridium difficile treatment, Evan S. Bradley, Emily Howe, Xun Wu, and John P. Haran

PDF

Investigating Potential Biomarkers in Autism Spectrum Disorder, Carolyn Bridgemohan, David E. Cochran, Andrew W. Zimmerman, Roula N. Choueiri, and Jean A. Frazier

PDF

A Persistence Detector for Metabolic Network Rewiring in an Animal, Jote T. Bulcha, Gabrielle E. Giese, Zulfikar Ali, Yong-Uk Lee, Melissa D. Walker, Amy D. Holdorf, L. Safak Yilmaz, Robert C. Brewster, and Albertha J. M. Walhout

Link

One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins, Michael A. Campitelli, Colleen J. Maxwell, Laura C. Maclagan, Dennis T. Ko, Chaim M. Bell, Lianne Jeffs, Andrew M. Morris, Kate L. Lapane, Nick Daneman, and Susan E. Bronskill

PDF

Diapause induces functional axonal regeneration after necrotic insult in C. elegans, Mauricio Caneo, Victoria Julian, Alexandra B. Byrne, Mark J. Alkema, and Andrea Calixto

PDF

Preferences, use of and satisfaction with mental health services among a sample of Puerto Rican cancer patients, Eida M. Castro-Figueroa, Normarie Torres-Blasco, Milagros C. Rosal, Wallesca P. Castro, Marilis E. Gonzalez-Lorenzo, Hector Velez, Rosario Costas-Muniz, and Julio C. Jimenez

PDF

Evaluation of prophylactic dosages of Enoxaparin in non-surgical elderly patients with renal impairment, Nibal Chamoun, Hady Ghanem, Ahmad Hachem, Essa Hariri, Christelle Lteif, Hanine Mansour, Hani Dimassi, Richard Zalloum, and Georges Ghanem

PDF

The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma, Benjamin J. Chen, Ravi Dashnamoorthy, Pallavi Galera, Vladislav Makarenko, Hong Chang, Srimoyee Ghosh, and Andrew M. Evens

PDF

Detecting Hypoglycemia Incidents Reported in Patients' Secure Messages: Using Cost-Sensitive Learning and Oversampling to Reduce Data Imbalance, Jinying Chen, John Lalor, Weisong Liu, Emily Druhl, Edgard A. Granillo, Varsha G. Vimalananda, and Hong Yu

PDF

The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine, Hyoung-Soo Cho, Andrea Reboldi, Jason A. Hall, and Leslie J. Berg

PDF

The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis, Sungwook Choi and Victor R. Ambros

PDF

Toll family members bind multiple Spatzle proteins and activate antimicrobial peptide gene expression in Drosophila, Munmun Chowdhury, Chun-Feng Li, Zhen He, Yuzhen Lu, Xu-Sheng Liu, Yu-Feng Wang, Y. Tony Ip, Michael R. Strand, and Xiao-Qiang Yu

PDF

Nonnative structure in a peptide model of the unfolded state of SOD1: Implications for ALS-linked aggregation, Noah R. Cohen, Jill A. Zitzewitz, Osman Bilsel, and C. Robert Matthews

PDF

The relation between mental health problems and future violence among detained male juveniles, Olivier F. Colins and Thomas Grisso

PDF

Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis, Johnathan Cooper-Knock, John E. Landers, and Pamela J. Shaw

PDF

JNK and cardiometabolic dysfunction, Siobhan M. Craige, Kai Chen, Robert M. Blanton, John F. Keaney Jr., and Shashi Kant

PDF

Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting, Anthony D. Cristillo and Peter A. Rice

Link

BID-ding on necroptosis in MDS, Ben A. Croker and Michelle A. Kelliher

PDF

Comparison of Immune Responses to Different Versions of VLP Associated Stabilized RSV Pre-Fusion F Protein, Lori M. Cullen, Madelyn R. Schmidt, Gretel M. Torres, Adam A. Capoferri, and Trudy G. Morrison

PDF

Harnessing robotic automation and web-based technologies to modernize scientific outreach, Orna Dahan, Bat-Shahar Dorfman, Serkan Sayin, Brittany Rosener, Tiffany Hua, Anat Yarden, and Amir Mitchell

PDF

Accelerated knee osteoarthritis is associated with pre-radiographic degeneration of the extensor mechanism and cruciate ligaments: data from the Osteoarthritis Initiative, Julie E. Davis, Matthew S. Harkey, Robert J. Ward, James W. MacKay, Bing Lu, Lori Lyn Price, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Timothy E. McAlindon, and Jeffrey B. Driban

PDF

A Fifty-Two-Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis, Atul Deodhar, Lianne S. Gensler, Jonathan Kay, Walter P. Maksymowych, Nigil Haroon, Robert Landewe, Martin Rudwaleit, Stephen Hall, Lars Bauer, Bengt Hoepken, Natasha de Peyrecave, Brian Kilgallen, and Desiree van der Heijde

PDF

Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment, Vishnu Dileep, Rachel Patton McCord, Job Dekker, and David M. Gilbert

PDF

High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network, Antje Dittmann, Norman J. Kennedy, Nina L. Soltero, Nader Morshed, Miyeko D. Mana, Omer H. Yilmaz, Roger J. Davis, and Forest M. White

PDF

Correction of pseudoexon splicing caused by a novel intronic dysferlin mutation, Janice A. Dominov, Ozgun Uyan, Diane McKenna-Yasek, Babi Ramesh Reddy Nallamilli, Virginie Kergourlay, Marc Bartoli, Nicolas Levy, Judith Hudson, Teresinha Evangelista, Hanns Lochmuller, Martin Krahn, Laura Rufibach, Madhuri Hegde, and Robert H. Brown Jr.

PDF

Elbow Ulnar Collateral Ligament Reconstruction Using the Novel Docking Plus Technique in 324 Athletes, Benjamin F. Donohue, Marc G. Lubitz, and Timothy E. Kremchek

PDF

The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH), Hannah K. Drescher, Ralf Weiskirchen, Annabelle Fulop, Carsten Hopf, Estibaliz Gonzalez de San Roman, Pitter F. Huesgen, Alain de Bruin, Laura Bongiovanni, Anette Christ, Rene Tolba, Christian Trautwein, and Daniela C. Kroy

PDF

An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting, Hesham Elhalawani, Thomas J. Fitzgerald, Fran Laurie, Kenneth Ulin, Roy Decker, Charles R. Thomas Jr., and Clifton D. Fuller

PDF

Differential Role of Pontomedullary Glutamatergic Neuronal Populations in Sleep-Wake Control, Evelyn T. M. Erickson, Loris L. Ferrari, Heinrich S. Gompf, and Christelle Anaclet

PDF

A cross-sectional analysis of factors associated with detection of oncogenic human papillomavirus in human immunodeficiency virus-infected and uninfected Kenyan women, A. Ermel, P. Tonui, M. Titus, Y. Tong, N. Wong, J. Ong'echa, K. Muthoka, S. Kiptoo, Ann M. Moormann, J. Hogan, A. Mwangi, S. Cu-Uvin, P. J. Loehrer, O. Orang'o, and D. Brown

PDF

The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus, David Ermert, Maisem Laabei, Antonin Weckel, Matthias Morgelin, Martin Lundqvist, Lars Bjorck, Sanjay Ram, Sara Linse, and Anna M. Blom

PDF

OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism, Xiaofei E, Paul Meraner, Ping Lu, Jill M. Perreira, Aaron M. Aker, William M. McDougall, Ronghua Zhuge, Gary C. Chan, Rachel M. Gerstein, Patrizia Caposio, Andrew D. Yurochko, Abraham L. Brass, and Timothy F. Kowalik

PDF

Methodology of an exercise intervention program using social incentives and gamification for obese children, Yue Fang, Yunsheng Ma, Dandan Mo, Shunxing Zhang, Mi Xiang, and Zhiruo Zhang

PDF

GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions, Maha R. Farhat, Luca Freschi, Roger Calderon, Thomas Ioerger, Matthew Snyder, Conor J. Meehan, Bouke de Jong, Leen Rigouts, Alexander Sloutsky, Devinder Kaur, Shamil Sunyaev, Dick van Soolingen, Jay Shendure, Jim Sacchettini, and Megan Murray

PDF

Dissemination and Effectiveness of the Peer Marketing and Messaging of a Web-Assisted Tobacco Intervention: Protocol for a Hybrid Effectiveness Trial, Jamie Faro, Elizabeth Aaker Orvek, Amanda C. Blok, Catherine S. Nagawa, Annalise J. McDonald, Gregory Seward, Thomas K. Houston, Ariana Kamberi, Jeroan J. Allison, Sharina D. Person, Tina Grosowsky, and Rajani S. Sadasivam

PDF

Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients, Matthew J. Fasullo, Prashanth Rau, Dong-Qi Liu, Erik Holzwanger, Jomol Mathew, Yurima Guilarte-Walker, and Gyongyi Szabo

PDF

Multimodal quantitative imaging of brain cancer in cultured cells, Xin Feng, Alona Muzikansky, Alonzo H. Ross, Michael R. Hamblin, Peter R. Jermain, and Anna N. Yaroslavsky

PDF

A data citation roadmap for scholarly data repositories, Martin Fenner, Merce Crosas, Jeffrey S. Grethe, David N. Kennedy, Henning Hermjakob, Phillippe Rocca-Serra, Gustavo Durand, Robin Berjon, Sebastian Karcher, Maryann Martone, and Tim Clark

PDF

Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females, Sully Fernandez, John M. Viola, AnnMarie Torres, Martina Wallace, Sophie Trefely, Steven Zhao, Hayley C. Affronti, Jivani M. Gengatharan, David A. Guertin, Nathaniel W. Snyder, Christian M. Metallo, and Kathryn E. Wellen

PDF

Outcomes and outcome measures used in evaluation of communication training in oncology - a systematic literature review, an expert workshop, and recommendations for future research, F. Fischer, S. Helmer, A. Rogge, J. I. Arraras, A. Buchholz, A. Hannawa, M. Horneber, A. Kiss, Matthias S. F. Rose, W. Sollner, B. Stein, J. Weis, P. Schofield, and C. M. Witt

PDF

Minimal Associations Between Clinical Data and Children's Self-Reported Health-Related Quality of Life in Children With Chronic Conditions-A Cross-Sectional Study, Kathrin I. Fischer, Dana Barthel, Christiane Otto, Ulrike Ravens-Sieberer, Ute Thyen, Marcus Klein, Otto Walter, Matthias S. F. Rose, and Sandra Nolte

PDF

Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1, Vera Fridman, Saranya Suriyanarayanan, Peter Novak, William David, Eric A. Macklin, Diane McKenna-Yasek, Kailey Walsh, Razina Aziz-Bose, Anne Louise Oaklander, Robert H. Brown Jr., Thorsten Hornemann, and Florian Eichler

Link

Aberrant splicing contributes to severe alpha-spectrin-linked congenital hemolytic anemia, Patrick G. Gallagher and Peter E. Newburger

Link

The emergence of pathogenic TNF/iNOS producing dendritic cells (Tip-DCs) in a malaria model of acute respiratory distress syndrome (ARDS) is dependent on CCR4, Bruno Galvao-Filho, Julia Teixeira de Castro, Maria Marta Figueiredo, Claudio Goncalves Rosmaninho, Lis Ribeiro do Valle Antonelli, and Ricardo T. Gazzinelli

PDF

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies, Matthew R. Gardner, Ina Fetzer, Lisa M. Kattenhorn, Meredith E. Davis-Gardner, Amber S. Zhou, Barnett Alfant, Jesse A. Weber, Hema R. Kondur, Jose M. Martinez-Navio, Sebastian P. Fuchs, Ronald C. Desrosiers, Guangping Gao, Jeffrey D. Lifson, and Michael Farzan

PDF

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome, Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker, and Neil Brockdorff

PDF

Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development, Ryan M. Genga, Eric M. Kernfeld, Krishna M. Parsi, Teagan J. Parsons, Michael J. Ziller, and Rene Maehr

PDF

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis, Anthony Giampetruzzi, Eric W. Danielson, Valentina Gumina, Maryangel Jeon, Sivakumar Boopathy, Robert H. Brown Jr., Antonia Ratti, John E. Landers, and Claudia Fallini

PDF

Citalopram in first episode schizophrenia: The DECIFER trial, Donald C. Goff and Xiaoduo Fan

PDF

Comparison of a Potential Hospital Quality Metric With Existing Metrics for Surgical Quality-Associated Readmission, Laura A. Graham, Hillary J. Mull, Todd H. Wagner, Melanie S. Morris, Amy K. Rosen, Joshua S. Richman, Jeffery Whittle, Edith Burns, Laurel A. Copeland, Kamal M. F. Itani, and Mary T. Hawn

PDF

Impact of pharmacogenomics on clinical outcomes in major depressive disorder in the GUIDED trial: A large, patient- and rater-blinded, randomized, controlled study, John F. Greden and Anthony J. Rothschild

PDF

Gene expression signature of atypical breast hyperplasia and regulation by SFRP1, Kelly J. Gregory, Giovanna M. Crisi, Brooke A. Bentley, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl J. Simin, Jacob P. S. Johnson, Ashraf Khan, Sallie S. Schneider, and D. Joseph Jerry

PDF

Bridging from Intramuscular to Limb Perfusion Delivery of rAAV: Optimization in a Non-human Primate Study, Alisha Gruntman, Gwladys Gernoux, Qiushi Tang, Guo-Jie Ye, Dave R. Knop, Gensheng Wang, Janet Benson, Kristen E. Coleman, Allison M. Keeler, Christian Mueller, Louis G. Chicoine, Jeffrey D. Chulay, and Terence R. Flotte

PDF

Perspectives of health educators and interviewers in a randomized controlled trial of a postpartum diabetes prevention program for Latinas: a qualitative assessment, Aline Gubrium, Denise Leckenby, Megan Ward Harvey, Bess H. Marcus, Milagros C. Rosal, and Lisa Chasan-Taber

PDF

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody, Sunita Gulati, Frank J. Beurskens, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Nancy Nowak, Peter A. Rice, and Sanjay Ram

PDF

Targeting Lipooligosaccharide (LOS) for a Gonococcal Vaccine, Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram, and Peter A. Rice

PDF

Association Between Alcohol Use Disorders and Outcomes of Patients Hospitalized With Community-Acquired Pneumonia, Niyati M. Gupta, Peter K. Lindenauer, Pei-Chun Yu, Peter B. Imrey, Sarah Haessler, Abhishek Deshpande, Thomas L. Higgins, and Michael B. Rothberg

PDF

Human islets expressing HNF1A variant have defective beta cell transcriptional regulatory networks, Rachana Haliyur, Sambra D. Redick, David M. Harlan, and Alvin C. Powers

PDF

Transfer RNA Genes Affect Chromosome Structure and Function via Local Effects, Omar Hamdani, Tsung-Han S. Hsieh, Oliver J. Rando, and Rohinton T. Kamakaka

PDF

Streptolysin O Induces the Ubiquitination and Degradation of Pro-IL-1beta, Dora Hancz, Elsa Westerlund, Christine Valfridsson, Getachew Melkamu Aemero, Benedicte Bastiat-Sempe, M. Pontus A. Orning, Egil Lien, Michael R. Wessels, and Jenny J. Persson

PDF

Alzheimer's Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway, John P. Haran, Shakti K. Bhattarai, Sage Foley, Protiva Dutta, Doyle V. Ward, Vanni Bucci, and Beth A. McCormick

PDF

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition, Reka A. Haraszti, Rachael Miller, Michelle L. Dubuke, Andrew H. Coles, Marie C. Didiot, Dimas Echeverria, Matteo Stoppato, Yves Y. Sere, John D. Leszyk, Julia F. Alterman, Bruno M. D. C. Godinho, Matthew R. Hassler, Rachel Wollacott, Yan Wang, Scott A. Shaffer, Neil Aronin, and Anastasia Khvorova

PDF

Lipoprotein(a) plasma levels, bone mineral density and risk of hip fracture: a post hoc analysis of the Women's Health Initiative, USA, Bernhard Haring, Carolyn J. Crandall, Laura Carbone, Simin Liu, Wenjun Li, Karen C. Johnson, Jean Wactawski-Wende, Aladdin H. Shadyab, Margery L. Gass, Victor Kamensky, Jane A. Cauley, and Sylvia Wassertheil-Smoller

PDF

Early pre-radiographic structural pathology precedes the onset of accelerated knee osteoarthritis, Matthew S. Harkey, Julie E. Davis, Bing Lu, Lori Lyn Price, Robert J. Ward, James W. MacKay, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Ming Zhang, Jincheng Pang, Alina C. Stout, Timothy E. McAlindon, and Jeffrey B. Driban

PDF

Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry, Leslie R. Harrold, Jenny Griffith, Patrick Zueger, Heather J. Litman, Bernice Gershenson, Syed S. Islam, Christine J. Barr, Dianlin Guo, Jonathan Fay, and Jeffrey D. Greenberg

PDF

Becoming Doctors: Examining Student Narratives to Understand the Process of Professional Identity Formation Within a Learning Community, David S. Hatem and Thomas Halpin

PDF

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity, Anne Margriet Heijink, Marieke Everts, Megan E. Honeywell, Ryan Richards, Yannick P. Kok, Elisabeth G. E. de Vries, Michael J. Lee, and Marcel A T M van Vugt

PDF

The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis, Christopher C. Hemond, Bonnie I. Glanz, Rohit Bakshi, Tanuja Chitnis, and Brian C. Healy

PDF

Barriers and Facilitators to Genetic Testing for Familial Hypercholesterolemia in the United States: A Review, Rachele M. Hendricks-Sturrup, Kathleen M. Mazor, Amy C. Sturm, and Christine Y. Lu

PDF

Alternative splicing regulates stochastic NLRP3 activity, Florian Hoss, James L. Mueller, Francisca Rojas Ringeling, Juan F. Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D. Putnam, Richard D. Kolodner, Stefan Canzar, Matthias Geyer, Hal M. Hoffman, and Eicke Latz

PDF

Gain-of-function mutations in the UNC-2/CaV2alpha channel lead to excitation-dominant synaptic transmission in C. elegans, Yung-Chi Huang, Jennifer K. Pirri, Diego Rayes, Shangbang Gao, Ben Mulcahy, Jeff Grant, Yasunori Saheki, Michael M. Francis, Mei Zhen, and Mark J. Alkema

PDF

A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis, Carmen Hurtado Del Pozo, Randall H. Friedline, Hye Lim Noh, Jason K. Kim, and Ann Marie. Schmidt

PDF

Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement, Peter J. Hutchinson and Susanne Muehlschlegel

PDF

Preformulation Characterization and Stability Assessments of Secretory IgA Monoclonal Antibodies as Potential Candidates for Passive Immunization by Oral Administration, Yue Hu, Ozan S. Kumru, Jian Xiong, Lorena R. Antunez, John Hickey, Yang Wang, Lisa Cavacini, Mark S. Klempner, Sangeeta B. Joshi, and David B. Volkin

PDF

A Comprehensive Review of Pegvaliase, an Enzyme Substitution Therapy for the Treatment of Phenylketonuria, Tasmina Hydery and Valerie Azzopardi Coppenrath

PDF

Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes, Robert J. Ihry, Zinger Yang, and Ajamete Kaykas