Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2018

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Bayesian nonparametric discovery of isoforms and individual specific quantification, Derek Aguiar, Li-Fang Cheng, Bianca Dumitrascu, Fantine Mordelet, Athma A. Pai, and Barbara E. Engelhardt

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Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation, Maria L. Allende, Emily K. Cook, Bridget C. Larman, Adrienne Nugent, Jacqueline M. Brady, Diane Golebiowski, Miguel Sena-Esteves, Cynthia J. Tifft, and Richard L. Proia

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New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge, Ana Paula M. M. Almeida, Leopoldo F.M. Machado, Daniel Doro, Frederico C. Nascimento, Leonardo Damasceno, Ricardo T. Gazzinelli, Ana Paula Fernandes, and Caroline Junqueira

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Haplotype analysis of APOE intragenic SNPs, Vladimir N. Babenko, Dmitry A. Afonnikov, Elena V. Ignatieva, Anton V. Klimov, Fedor E. Gusev, and Evgeny I. Rogaev

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Evaluation of a method to measure HHV-6B infection in vitro based on cell size, Aniuska Becerra, Tessa Santoro, and Lawrence J. Stern

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Safety and efficacy of subcutaneous tanezumab in patients with knee or hip osteoarthritis, Charles Birbara, Eugene J. Dabezies Jr, Aimee M. Burr, Robert J. Fountaine, Michael D. Smith, Mark T. Brown, Christine R. West, Rosalin H. Arends, and Kenneth M. Verburg

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Study protocol: a hybrid effectiveness-implementation trial of Moral Reconation Therapy in the US Veterans Health Administration, Daniel M. Blonigen, Michael A. Cucciare, Christine Timko, Jennifer S. Smith, Autumn Harnish, Lakiesha Kemp, Joel Rosenthal, and David A. Smelson

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alpha Cell Function and Gene Expression Are Compromised in Type 1 Diabetes, Marcela Brissova, David Blodgett, Dale L. Greiner, David M. Harlan, and Alvin C. Powers

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Bow Hunter's Syndrome in a Patient with a Right Hypoplastic Vertebral Artery and a Dynamically Compressible Left Vertebral Artery, David Z. Cai, Ryan P. Roach, John P. Weaver, Gerald T. McGillicuddy, Zachary M. Mansell, Jonathan P. Eskander, and Mark S. Eskander

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Time management in a co-housed social rodent species (Arvicanthis niloticus), Alexandra Castillo-Ruiz, Premananda Indic, and William J. Schwartz

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Evolution of extrema features reveals optimal stimuli for biological state transitions, Joshua TsuKang Chang and David Paydarfar

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Robot-Assisted Thoracoscopic Resection of a Posterior Mediastinal Mullerian Cyst, Calvin Chao, Vijay K. Vanguri, and Karl Uy

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C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2alpha phosphorylation, Weiwei Cheng, Shaopeng Wang, Alexander A. Mestre, Chenglai Fu, Andres Makarem, Fengfan Xian, Lindsey R. Hayes, Rodrigo Lopez-Gonzalez, Kevin Drenner, Jie Jiang, Don W. Cleveland, and Shuying Sun

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Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis, Qingbo Chen, Lei Huang, Dongning Pan, Lihua (Julie) Zhu, and Yong-Xu Wang

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Paternal exposure to medical-related radiation associated with low birthweight infants: A large population-based, retrospective cohort study in rural China, Shi Chen, Bill Q. Lian, and Hui Pan

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Immunocontraceptive target repertoire defined by systematic identification of sperm membrane alloantigens in a single species, Nathaly Cormier, John J. McGlone, John D. Leszyk, and Daniel M. Hardy

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A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef, Weiwei Dai, Yoshiko Usami, Yuanfei Wu, and Heinrich G. Gottlinger

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Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus, Priyadharshini Devarajan, Michael C. Jones, Olivia Kugler-Umana, Allen M. Vong, Jingya Xia, and Susan L. Swain

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The principles and practice of open fracture care, 2018, Amna Diwan, Kyle R. Eberlin, and Raymond Malcolm Smith

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Hodgkin Lymphoma: Differences in Treatment Between Europe and the United States/North America: Evolving Trends in Protocol Therapy, Thomas J. Fitzgerald and Maryann Bishop-Jodoin

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Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila, Pooja Flora, Sean Schowalter, SiuWah Wong-Deyrup, Matthew DeGennaro, Mohamad Ali Nasrallah, and Prashanth Rangan

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Metastatic Extramammary Paget's Disease: Pathogenesis and Novel Therapeutic Approach, Keitaro Fukuda and Takeru Funakoshi

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The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology, Yu Fu, Yujing Yang, Han Zhang, Gwen Farley, Junling Wang, Kaycee A. Quarles, Zhiping Weng, and Phillip D. Zamore

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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018, Lorenzo Galluzzi, Eric H. Baehrecke, Francis Ka-Ming Chan, and Guido Kroemer

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Excitatory motor neurons are local oscillators for backward locomotion, Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Taizo Kawano, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen

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Device Therapies Among Patients Receiving Primary Prevention Implantable Cardioverter-Defibrillators in the Cardiovascular Research Network, Robert T. Greenlee, Jerry H. Gurwitz, and David D. McManus

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Patterns of civilian and child deaths due to war-related violence in Syria: a comparative analysis from the Violation Documentation Center dataset, 2011-16, Debarati Guha-Sapir, Benjamin Schluter, Jose Manuel Rodriguez-Llanes, Louis Lillywhite, and Madelyn J. Hsiao-Rei Hicks

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A large-scale RNA interference screen identifies genes that regulate autophagy at different stages, Sujuan Guo, Kevin J. Pridham, Ching-Man A. Virbasius, Bin He, Liqing Zhang, Hanne Varmark, Michael R. Green, and Zhi Sheng

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Research evaluation support services in biomedical libraries, Karen Elizabeth Gutzman, Michael E. Bales, Christopher W. Belter, Thane Chambers, Liza Chan, Kristi L. Holmes, Ya-Ling Lu, Lisa A. Palmer, Rebecca Reznik-Zellen, Cathy C. Sarli, Amy M. Suiter, and Terrie R. Wheeler

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Determining the scope of attacks on health in four governorates of Syria in 2016: Results of a field surveillance program, Rohini J. Haar, Casey B. Risko, Sonal Singh, Diana Rayes, Ahmad Albaik, Mohammed Alnajar, Mazen Kewara, Emily Clouse, Elise Baker, and Leonard S. Rubenstein

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The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation, Shahrad Hakimian, Yevgeniy Popov, Abbas Rupawala, Karen I. Salomon-Escoto, Steven Hatch, and Randall Pellish

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Effect of Anticitrullinated Protein Antibody Status on Response to Abatacept or Antitumor Necrosis Factor-alpha Therapy in Patients with Rheumatoid Arthritis: A US National Observational Study, Leslie R. Harrold, Heather J. Litman, Sean E. Connolly, Sheila Kelly, Winnie Hua, Evo Alemao, Lisa Rosenblatt, Sabrina Rebello, and Joel M. Kremer

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One-year risk of serious infection in patients treated with certolizumab pegol as compared with other TNF inhibitors in a real-world setting: data from a national U.S. rheumatoid arthritis registry, Leslie R. Harrold, Heather J. Litman, Katherine C. Saunders, Kimberly J. Dandreo, Bernice Gershenson, Jeffrey D. Greenberg, Robert Low, Jeffrey Stark, Robert Suruki, Srihari Jaganathan, Joel M. Kremer, and Mohamed Yassine

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Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach to Care of US Patients With Rheumatoid Arthritis, Leslie R. Harrold, George W. Reed, Ani John, Christine J. Barr, Kevin Soe, Robert P. Magner, Katherine C. Saunders, Eric M. Ruderman, Tmirah Haselkorn, Jeffrey D. Greenberg, Allan Gibofsky, J. Timothy Harrington, and Joel M. Kremer

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Cystic fibrosis-related diabetes is caused by islet loss and inflammation, Nathaniel J. Hart, Jenny Aurielle B. Babon, Megan E. DeNicola, Sally C. Kent, and Alvin C. Powers

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Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo, Matthew R. Hassler, Anton A. Turanov, Julia F. Alterman, Reka A. Haraszti, Andrew H. Coles, Maire F. Osborn, Dimas Echeverria, Mehran Nikan, William E. Salomon, Loic Roux, Bruno M. D. C. Godinho, Sarah M. Davis, David V. Morrissey, Phillip D. Zamore, S. Ananth Karumanchi, Melissa J. Moore, Neil Aronin, and Anastasia Khvorova

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SeekDeep: single-base resolution de novo clustering for amplicon deep sequencing, Nicholas J. Hathaway, Christian M. Parobek, Jonathan J. Juliano, and Jeffrey A. Bailey

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Down-regulation of microRNA-203-3p initiates type 2 pathology during schistosome infection via elevation of interleukin-33, Xing He, Jun Xie, Yange Wang, Xiaobin Fan, Qin Su, Yue Sun, Nanhang Lei, Dongmei Zhang, Guangping Gao, and Weiqing Pan

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Identification of Epigenetic Regulators of DUX4-fl for Targeted Therapy of Facioscapulohumeral Muscular Dystrophy, Charis L. Himeda, Takako I. Jones, Ching-Man A. Virbasius, Lihua Julie Zhu, Michael R. Green, and Peter L. Jones

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Autologous/Allogeneic Hematopoietic Cell Transplantation versus Tandem Autologous Transplantation for Multiple Myeloma: Comparison of Long-Term Postrelapse Survival, Myo Htut, Muthalagu Ramanathan, and Parameswaran Hari

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Biochemical Analysis of Dimethyl Suberimidate-crosslinked Yeast Nucleosomes, Yuichi Ichikawa and Paul D. Kaufman

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A cre-inducible DUX4 transgenic mouse model for investigating facioscapulohumeral muscular dystrophy, Takako I. Jones and Peter L. Jones

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Prognostic role of elevated mir-24-3p in breast cancer and its association with the metastatic process, Alireza Khodadadi-Jamayran, Betul Akgol-Oksuz, Yelena Afanasyeva, Adriana Heguy, Marae Thompson, Karina Ray, Ariadna Giro-Perafita, Irma Sanchez, Xifeng Wu, Debu Tripathy, Anne Zeleniuch-Jacquotte, Aristotelis Tsirigos, and Francisco J. Esteva

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Understanding the Digital Gap Among US Adults With Disability: Cross-Sectional Analysis of the Health Information National Trends Survey 2013, Eun Ji Kim, Yiyang Yuan, Jane Liebschutz, Howard Cabral, and Lewis Kazis

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Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Tianxiao Huan, Lauren Clancy, Ravi Shah, Emelia J. Benjamin, Daniel Levy, Evelyn A. Kurt-Jones, Kahraman Tanriverdi, and Jane E. Freedman

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Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity, Milka Koupenova-Zamor and Katya Ravid

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A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1), Tomohiro Kubo, Yuqing Hou, Deborah A. Cochran, George B. Witman, and Toshiyuki Oda

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A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells, Andreas Kurtz, Stefanie Seltmann, and Kelly P. Smith

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Low-energy Bluetooth for detecting real-world penetrance of bystander naloxone kits: a pilot study, Jeffrey T. Lai, Brittany Chapman, Katherine L. Boyle, Edward W. Boyer, and Peter R. Chai

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ComprehENotes, an Instrument to Assess Patient Reading Comprehension of Electronic Health Record Notes: Development and Validation, John P. Lalor, Hao Wu, Li Chen, Kathleen M. Mazor, and Hong Yu

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Religiosity prevalence and its association with depression and anxiety symptoms among Hispanic/Latino adults, Shir Lerman, Molly Jung, Elva M. Arredondo, Janice M. Barnhart, Jianwen Cai, Sheila F. Castaneda, Martha L. Daviglus, Rebeca A. Espinoza, Aida L. Giachello, Kristine M. Molina, Krista Perreira, Hugo Salgado, Sylvia Wassertheil-Smoller, and Robert C. Kaplan

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Ephrinb3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpineinduced model of epilepsy, Tian-Tian Liu, Yi Li, Yi Shu, Bo Xiao, and Li Feng

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Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid, Xi Liu, Xing-Fang Hou, Lei Gao, Guo-Fang Deng, Ming-Xia Zhang, Qun-Yi Deng, Tao-Sheng Ye, Qian-Ting Yang, Bo-Ping Zhou, Zhi-Hua Wen, Hai-Ying Liu, Hardy Kornfeld, and Xin-Chun Chen

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Splenic Infarction: An Under-recognized Complication of Infectious Mononucleosis?, Yan Li, Ann George, Sami Arnaout, Jennifer P. Wang, and George M. Abraham

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Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs, Yi Lu, Phillip W. L. Tai, Jianzhong Ai, Dominic J. Gessler, Qin Su, Xieyi Yao, Qiang Zheng, Phillip D. Zamore, Xun Xu, and Guangping Gao

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Naltrexone and Bupropion Combination Treatment for Smoking Cessation and Weight Loss in Patients With Schizophrenia, Xuechan Lyu, Jiang Du, Guilai Zhan, Yujie Wu, Hang Su, Youwei Zhu, Fredrik Jarskog, Min Zhao, and Xiaoduo Fan

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Periostin and mesothelin: Potential predictors of malignant progression in intrahepatic cholangiocarcinoma, Pranoti Mandrekar and Vincenzo Cardinale

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Under one roof: identification, evaluation, and treatment of chronic hepatitis C in addiction care, Stephen A. Martin, Jordon Bosse, Amanda Wilson, Phyllis Losikoff, and Lisa Chiodo

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A parental requirement for dual-specificity phosphatase 6 in zebrafish, Jennifer M. Maurer and Charles G. Sagerstrom

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Code Help: Can This Unique State Regulatory Intervention Improve Emergency Department Crowding, Sean S. Michael, John Broach, Kevin A. Kotkowski, David Eric Brush, Gregory A. Volturo, and Martin A. Reznek

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JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory, Caroline Morel, Tessi Sherrin, Norman J. Kennedy, Kelly H. Forest, Seda Barutcu, Michael Robles, Ezekiel Carpenter-Hyland, Naghum Alfulaij, Claire L. Standen, Robert A. Nichols, Morris Benveniste, Roger J. Davis, and Cedomir Todorovic

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The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5alpha, Damien Morger, Franziska Zosel, Martin Buhlmann, Sara Zuger, Maximilian Mittelviefhaus, Benjamin Schuler, Jeremy Luban, and Markus G. Grutter

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Donated chemical probes for open science, Susanne Muller, Paul R. Thompson, and Anke Mueller-Fahrnow

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Clinical Relation Extraction Toward Drug Safety Surveillance Using Electronic Health Record Narratives: Classical Learning Versus Deep Learning, Tsendsuren Munkhdalai, Feifan Liu, and Hong Yu

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MYC amplification in subtypes of breast cancers in African American women, Tammey J. Naab, Anita Gautam, Luisel Ricks-Santi, Ashwini K. Esnakula, Yasmine M. Kanaan, Robert L. DeWitty, Girmay Asgedom, Khepher H. Makambi, Massih Abawi, and Jan K. Blancato

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N-terminal Sumoylation of Centromeric Histone H3 Variant Cse4 Regulates Its Proteolysis To Prevent Mislocalization to Non-centromeric Chromatin, Kentaro Ohkuni, Reuben Levy-Myers, Jack Warren, Wei-Chun Au, Yoshimitsu Takahashi, Richard E. Baker, and Munira A. Basrai

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Pilot Study of Delayed ICOS/ICOS-L Blockade With alphaCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model, Natalie A. O'Neill, Tianshu Zhang, Gheorghe Braileanu, Xiangfei Cheng, Alena Hershfeld, Wenji Sun, Keith A. Reimann, Sia Dahi, Natalia Kubicki, Wessam Hassanein, Christopher Laird, Arielle Cimeno, Agnes M. Azimzadeh, and Richard N. Pierson

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ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data, Jianhong Ou, Haibo Liu, Jun Yu, Michelle A. Kelliher, Lucio H. Castilla, Nathan D. Lawson, and Lihua Julie Zhu

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A comparative analysis of preservation techniques for the optimal molecular detection of hookworm DNA in a human fecal specimen, Marina Papaiakovou, Nils Pilotte, Ben Baumer, Jessica Grant, Kristjana Asbjornsdottir, Fabian Schaer, Yan Hu, Raffi V. Aroian, Judd Walson, and Steven A. Williams

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The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1, Maria Perez Carrion, John E. Landers, Stefano Goldwurm, and Giovanni Piccoli

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Ras hyperactivation versus overexpression: Lessons from Ras dynamics in Candida albicans, Vavilala A. Pratyusha, Guiliana Soraya Victoria, Mohammad Firoz Khan, Dominic T. Haokip, Bhawna Yadav, Nibedita Pal, Subhash Chandra Sethi, Priyanka Jain, Sneh Lata Singh, Sobhan Sen, and Sneha Sudha Komath

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Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia, John A. Pulikkan and Lucio H. Castilla

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Tuberculosis and lung damage: from epidemiology to pathophysiology, Shruthi Ravimohan, Hardy Kornfeld, Drew Weissman, and Gregory P. Bisson

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Using support vector machines on photoplethysmographic signals to discriminate between hypovolemia and euvolemia, Natasa Reljin, Gary Zimmer, Yelena Malyuta, Kirk Shelley, Yitzhak Mendelson, David J. Blehar, Chad E. Darling, and Ki H. Chon

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On the Demographic and Selective Forces Shaping Patterns of Human Cytomegalovirus Variation within Hosts, Andrew M. Sackman, Susanne P. Pfeifer, Timothy F. Kowalik, and Jeffrey D. Jensen

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Novel candidate genes important for asthma and hypertension comorbidity revealed from associative gene networks, Olga V. Saik, Pavel S. Demenkov, Timofey V. Ivanisenko, Elena Yu. Bragina, Maxim B. Freidin, Irina A. Goncharova, Victor E. Dosenko, Olga I. Zolotareva, Ralf Hofestaedt, Inna N. Lavrik, Evgeny I. Rogaev, and Vladimir A. Ivanisenko

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Integrating mindfulness training in school health education to promote healthy behaviors in adolescents: Feasibility and preliminary effects on exercise and dietary habits, Elena Salmoirago-Blotcher, Susan Druker, Christine F. Frisard, Shira I. Dunsiger, Sybil L. Crawford, Florence Meleo-Meyer, Beth Bock, and Lori Pbert

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Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma, Seijiro Sato, Stephen Lyle, Toshifumi Wakai, and Masanori Tsuchida

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Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma, Takashi Semba, Eiji Sugihara, Nagisa Kamoshita, Sayaka Ueno, Keitaro Fukuda, Masafumi Yoshino, Kazumasa Takao, Kazunori Yoshikawa, Kenji Izuhara, Yoshimi Arima, Makoto Suzuki, and Hideyuki Saya

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Prevalence and characteristics of sleep-disordered breathing in familial dysautonomia, Kanwaljit Singh, Jose-Alberto Palma, Horacio Kaufmann, Nataliya Tkachenko, Lucy Norcliffe-Kaufmann, Christy Spalink, Mikhail Kazachkov, and Sanjeev V. Kothare

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An evidence-based co-occurring disorder intervention in VA homeless programs: outcomes from a hybrid III trial, David A. Smelson, Matthew Chinman, Gordon Hannah, Thomas Byrne, and Sharon McCarthy

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What are the physical and psychological health effects of suicide bereavement on family members? An observational and interview mixed-methods study in Ireland, Ailbhe Spillane, Karen Matvienko-Sikar, Celine Larkin, Paul Corcoran, and Ella Arensman

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Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study, Laila Staerk, Biqi Wang, Sarah R. Preis, Martin G. Larson, Steven A. Lubitz, Patrick T. Ellinor, David D. McManus, Darae Ko, Lu-Chen Weng, Kathryn L. Lunetta, Lars Frost, Emelia J. Benjamin, and Ludovic Trinquart

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Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics, Barry L. Stoddard, Anastasia Khvorova, David R. Corey, William S. Dynan, and Keith R. Fox

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Serum anti-flagellin and anti-lipopolysaccharide immunoglobulins as predictors of linear growth faltering in Pakistani infants at risk for environmental enteric dysfunction, Sana Syed, Najeeha T. Iqbal, Kamran Sadiq, Jennie Z. Ma, Tauseef Akhund, Wenjun Xin, Sean R. Moore, Enju Liu, Shahida Qureshi, Kerri B. Gosselin, Andrew Gewirtz, Christopher P. Duggan, and S Asad. Ali

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Use of ELISpot assay to study HBs-specific B cell responses in vaccinated and HBV infected humans, Chen Tian, Yuxin Chen, Yong Liu, Shixia Wang, Yang Li, Guiyang Wang, Juan Xia, Xiang-An Zhao, Rui Huang, Shan Lu, and Chao Wu

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Ischemia augments alloimmune injury through IL-6-driven CD4(+) alloreactivity, Mayuko Uehara, Zhabiz Solhjou, Naima Banouni, Vivek Kasinath, Ye Xiaqun, Li Dai, Osman Yilmam, Mine Yilmaz, Takaharu Ichimura, Paolo Fiorina, Paulo N.A. Martins, Shunsuke Ohori, Indira Guleria, Omar H. Maarouf, Stefan G. Tullius, Martina M. McGrath, and Reza Abdi

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Population-based differences in the outcome and presentation of lung cancer patients based upon racial, histologic, and economic factors in all lung patients and those with metastatic disease, John M. Varlotto, Richard Voland, Kerrie McKie, John C. Flickinger, Malcolm M. DeCamp, Debra Maddox, Paul Rava, Thomas J. Fitzgerald, Geoffrey Graeber, Negar Rassaei, Paulo Oliveira, Suhail Ali, Chandra Belani, Jonathan Glanzman, Heather A. Wakelee, Manali Patel, Jennifer Baima, Jianying Zhang, and William Walsh

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Thermophilic Adaptation in Prokaryotes Is Constrained by Metabolic Costs of Proteostasis, Sergey V. Venev and Konstantin B. Zeldovich

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Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma, Arvind Venkatesan, Rajesh Vyas, Alec Gramann, Karen A. Dresser, Sharvari Gujja, Sanchita Bhatnagar, Sagar Chhangawala, Camilla Borges Ferreira Gomes, Hualin Simon Xi, Christine G. Lian, Yariv Houvras, Yvonne J. K. Edwards, April C. Deng, Michael R. Green, and Craig J. Ceol

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Increasing Resistance to Azithromycin in Neisseria gonorrhoeae in Eastern Chinese Cities: Resistance Mechanisms and Genetic Diversity among Isolates from Nanjing, Chuan Wan, Yang Li, Wen-Jing Le, Yu-Rong Liu, Sai Li, Bao-Xi Wang, Peter A. Rice, and Xiao-Hong Su

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Deconvolution of subcellular protrusion heterogeneity and the underlying actin regulator dynamics from live cell imaging, Chuangqi Wang, Hee June Choi, Sung-Jin Kim, Aesha Desai, Namgyu Lee, Dohoon Kim, Yongho Bae, and Kwonmoo Lee

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A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates, Dan Wang, Shaoyong Li, Dominic J. Gessler, Jun Xie, Li Zhong, Jia Li, Karen Tran, Kim Van Vliet, Lingzhi Ren, Qin Su, Ran He, Jason E. Goetzmann, Terence R. Flotte, Mavis Agbandje-McKenna, and Guangping Gao

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Similarity of chest X-ray and thermal imaging of focal pneumonia: a randomised proof of concept study at a large urban teaching hospital, Linda T. Wang, Robert H. Cleveland, William Binder, Robert G. Zwerdling, Caterina Stamoulis, Thomas Ptak, Mindy Sherman, Kenan Haver, Pallavi Sagar, and Patricia Hibberd

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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy, Minan Wang, Michael A. Brehm, and Dale L. Greiner

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Fundamental limits on dynamic inference from single-cell snapshots, Caleb Weinreb, Samuel Wolock, Betsabeh K. Tusi, Merav Socolovsky, and Allon M. Klein

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Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: A systematic literature review and meta-analysis, Chih-Hsing Wu, Shih-Te Tu, Yin-Fan Chang, Ding-Cheng Chan, Jui-Teng Chien, Chih-Hsueh Lin, Sonal Singh, Manikanta Dasari, Jung-Fu Chen, and Keh-Sung Tsai

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Efficient Blue to Red Afterglow Tuning in a Binary Nanocomposite Plastic Film, Yan Xia, Huase Ou, Wanbin Li, Gang Han, and Zhanjun Li

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Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages, Jinglian Yan, Guodong Tie, Shoying Wang, Amanda A. Tutto, Natale DeMarco, Lyne Khair, Thomas G. Fazzio, and Louis M. Messina