Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2018

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Impact of delirium on patients hospitalized for myocardial infarction: A propensity score analysis of the National Inpatient Sample, Abdullah Abdullah, George Eigbire, Amr Salama, Abdul Wahab, Mohanad Awadalla, Ryan Hoefen, and Richard Alweis

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TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis, Diwash Acharya, Bernadette Nera, Zachary J. Milstone, Lauren Bourke, Yeonsoo Yoon, Jaime A. Rivera-Pérez, Chinmay M. Trivedi, and Thomas G. Fazzio

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Reduced Incidence and Better Liver Disease Outcomes among Chronic HCV Infected Patients Who Consume Cannabis, Adeyinka Adejumo, Oluwole Muyiwa Adegbala, Kelechi Lauretta Adejumo, and Terence N. Bukong

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Bayesian nonparametric discovery of isoforms and individual specific quantification, Derek Aguiar, Li-Fang Cheng, Bianca Dumitrascu, Fantine Mordelet, Athma A. Pai, and Barbara E. Engelhardt

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The Morbidity and Mortality of Laparoscopic Appendectomy in Patients with Cirrhosis, Yasir Al-Azzawai, Yasir Al-Abboodi, Matthew J. Fasullo, and Tarek Najuib

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The comparative genomics of Bifidobacterium callitrichos reflects dietary carbohydrate utilization within the common marmoset gut, Korin Albert, Asha Rani, and David A. Sela

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Draft Genome Sequence of Bifidobacterium longum UMA026, Isolated from Holstein Dairy Cow Feces, Korin Albert and David Sela

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A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release, Constanza Alcaino, Kaitlyn R. Knutson, Anthony J. Treichel, Gulcan Yildiz, Peter R. Strege, David R. Linden, Joyce H. Li, Andrew B. Leiter, Joseph H. Szurszewski, Gianrico Farrugia, and Arthur Beyder

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Do Poor Prognostic Factors in Rheumatoid Arthritis Affect Treatment Choices and Outcomes? Analysis of a US Rheumatoid Arthritis Registry, Evo Alemao, Heather J. Litman, Sean E. Connolly, Sheila Kelly, Winnie Hua, Lisa Rosenblatt, Sabrina Rebello, Joel M. Kremer, and Leslie R. Harrold

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Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation, Maria L. Allende, Emily K. Cook, Bridget C. Larman, Adrienne Nugent, Jacqueline M. Brady, Diane Golebiowski, Miguel Sena-Esteves, Cynthia J. Tifft, and Richard L. Proia

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New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge, Ana Paula M. M. Almeida, Leopoldo F.M. Machado, Daniel Doro, Frederico C. Nascimento, Leonardo Damasceno, Ricardo T. Gazzinelli, Ana Paula Fernandes, and Caroline Junqueira

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Genetic Activation, Inactivation, and Deletion Reveal a Limited And Nuanced Role for Somatostatin-Containing Basal Forebrain Neurons in Behavioral State Control, Christelle Anaclet, Roberto De Luca, Anne Venner, Olga Malyshevskaya, Michael Lazarus, Elda Arrigoni, and Patrick M. Fuller

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Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes, Ozkan Aydemir, Nicholas J. Hathaway, Patrick W. Marsh, Alice Tran, Thomas Reimonn, and Jeffrey A. Bailey

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Haplotype analysis of APOE intragenic SNPs, Vladimir N. Babenko, Dmitry A. Afonnikov, Elena V. Ignatieva, Anton V. Klimov, Fedor E. Gusev, and Evgeny I. Rogaev

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Macular phototoxicity after corneal cross-linking, Paulo Rodolfo Barbisan Tagliari, Marina Goncalves Viturino Monteiro, Fernanda Maria Souto Silveira, Bo Tian, Roberto Damian Pacheco Pinto, Lucas Barasnevicius Quagliato, Mauricio Abujamra Nascimento, Rosane Silvestre de Castro, and Carlos Eduardo Arieta Leite

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RIPK1-RIPK3-MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils, Laiana A. Barbosa, Paloma P. Fiuza, Leticia J. Borges, Fellipe A. Rolim, Mayara B. Andrade, Nivea F. Luz, Graziele Quintela-Carvalho, Jonilson B. Lima, Roque P. Almeida, Francis Ka-Ming Chan, Marcelo T. Bozza, Valeria M. Borges, and Deboraci B. Prates

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Anxiety, Depression, and Adverse Clinical Outcomes in Patients With Atrial Fibrillation Starting Warfarin: Cardiovascular Research Network WAVE Study, Christine Baumgartner, Dongjie Fan, Margaret C. Fang, Daniel E. Singer, Daniel M. Witt, John R. Schmelzer, Marc S. Williams, Jerry H. Gurwitz, Sue Hee Sung, and Alan S. Go

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Evaluation of a method to measure HHV-6B infection in vitro based on cell size, Aniuska Becerra, Tessa Santoro, and Lawrence J. Stern

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Are membranes non-apoptotic compartments for apoptotic caspases, Andreas Bergmann

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Allostatic Load Biomarker Associations with Depressive Symptoms Vary among US Black and White Women and Men, Ganga Bey, William M. Jesdale, Christine M. Ulbricht, Eric O. Mick, and Sharina D. Person

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Analysis and Correction of Inappropriate Image Duplication: the Molecular and Cellular Biology Experience, Elisabeth M. Bik, Ferric C. Fang, Amy L. Kullas, Roger J. Davis, and Arturo Casadevall

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Safety and efficacy of subcutaneous tanezumab in patients with knee or hip osteoarthritis, Charles Birbara, Eugene J. Dabezies Jr, Aimee M. Burr, Robert J. Fountaine, Michael D. Smith, Mark T. Brown, Christine R. West, Rosalin H. Arends, and Kenneth M. Verburg

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Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model, Jorge C. G. Blanco, Lioubov M. Pletneva, Lori McGinnes Cullen, Raymonde O. Otoa, Mira C. Patel, Lurds R. Fernando, Marina S. Boukhvalova, and Trudy G. Morrison

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Study protocol: a hybrid effectiveness-implementation trial of Moral Reconation Therapy in the US Veterans Health Administration, Daniel M. Blonigen, Michael A. Cucciare, Christine Timko, Jennifer S. Smith, Autumn Harnish, Lakiesha Kemp, Joel Rosenthal, and David A. Smelson

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Nasopharyngeal Exposure to Streptococcus pneumoniae Induces Extended Age-Dependent Protection against Pulmonary Infection Mediated by Antibodies and CD138(+) Cells, Elsa N. Bou Ghanem, Nang H. Maung, Nalat Siwapornchai, Aaron E. Goodwin, Stacie Clark, Ernesto J. Munoz-Elias, Andrew Camilli, Rachel M. Gerstein, and John M. Leong

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Synergistic assembly of human pre-spliceosomes across introns and exons, Joerg E. Braun, Larry J. Friedman, Jeff Gelles, and Melissa J. Moore

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Can Mindfulness Address Maladaptive Eating Behaviors? Why Traditional Diet Plans Fail and How New Mechanistic Insights May Lead to Novel Interventions, Judson A. Brewer, Andrea Ruf, Ariel Beccia, Gloria I. Essien, Leonard M. Finn, Remko van Lutterveld, and Ashley E. Mason

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alpha Cell Function and Gene Expression Are Compromised in Type 1 Diabetes, Marcela Brissova, David Blodgett, Dale L. Greiner, David M. Harlan, and Alvin C. Powers

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Maximising the global health impact of future HIV cure-related interventions through advance planning, Regina Brown, Steven G. Deeks, and Nir Eyal

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Unique surgical approach to a twisted ileal-anal pouch, Hannah Buettner, Maria X. Kiely, Mengdi Yao, James Yoo, and Lilian Chen

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Ajulemic acid: potential treatment for chronic inflammation, Sumner Burstein

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Bow Hunter's Syndrome in a Patient with a Right Hypoplastic Vertebral Artery and a Dynamically Compressible Left Vertebral Artery, David Z. Cai, Ryan P. Roach, John P. Weaver, Gerald T. McGillicuddy, Zachary M. Mansell, Jonathan P. Eskander, and Mark S. Eskander

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Time management in a co-housed social rodent species (Arvicanthis niloticus), Alexandra Castillo-Ruiz, Premananda Indic, and William J. Schwartz

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Evolution of extrema features reveals optimal stimuli for biological state transitions, Joshua TsuKang Chang and David Paydarfar

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Robot-Assisted Thoracoscopic Resection of a Posterior Mediastinal Mullerian Cyst, Calvin Chao, Vijay K. Vanguri, and Karl Uy

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C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2alpha phosphorylation, Weiwei Cheng, Shaopeng Wang, Alexander A. Mestre, Chenglai Fu, Andres Makarem, Fengfan Xian, Lindsey R. Hayes, Rodrigo Lopez-Gonzalez, Kevin Drenner, Jie Jiang, Don W. Cleveland, and Shuying Sun

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Treatment of Triple-Negative Breast Cancer Cells with the Canady Cold Plasma Conversion System: Preliminary Results, Xiaoqian Cheng, Warren Rowe, Lawan Ly, Alexey Shashurin, Taisen Zhuang, Shruti Wigh, Giacomo Basadonna, Barry Trink, Michael Keidar, and Jerome Canady

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Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis, Qingbo Chen, Lei Huang, Dongning Pan, Lihua (Julie) Zhu, and Yong-Xu Wang

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Both maternal and paternal risk factors for term singleton low birthweight infants in rural Chinese population: a population-based, retrospective cohort study, Shi Chen, Bill Q. Lian, and Hui Pan

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Paternal exposure to medical-related radiation associated with low birthweight infants: A large population-based, retrospective cohort study in rural China, Shi Chen, Bill Q. Lian, and Hui Pan

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Quantitative Profiling of the Lymph Node Clearance Capacity, Cristina C. Clement, Wei Wang, Monika Dzieciatkowska, Marco Cortese, Kirk C. Hansen, Aniuska Becerra, Sangeetha Thangaswamy, Irina Nizamutdinova, Jee-Young Moon, Lawrence J. Stern, Anatoliy A. Gashev, David Zawieja, and Laura Santambrogio

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Immunocontraceptive target repertoire defined by systematic identification of sperm membrane alloantigens in a single species, Nathaly Cormier, John J. McGlone, John D. Leszyk, and Daniel M. Hardy

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VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis, MacIntosh Cornwell, Mahesh Vangala, Len Taing, Zachary Herbert, Johannes Koster, Bo Li, Hanfei Sun, Taiwen Li, Jian Zhang, Xintao Qiu, Matthew Pun, Rinath Jeselsohn, Myles Brown, X Shirley Liu, and Henry W. Long

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A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef, Weiwei Dai, Yoshiko Usami, Yuanfei Wu, and Heinrich G. Gottlinger

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Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction, Kirsty M. Danielson, Kahraman Tanriverdi, Jane E. Freedman, and Saumya Das

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Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial, Maria I. Danila, Jeroan J. Allison, Frederick A. Anderson Jr., Allison Wyman, and Kenneth G. Saag

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ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function, Martina de Majo, Kevin P. Kenna, Robert H. Brown Jr., John E. Landers, and Christopher E. Shaw

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Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling, Dominic De Nardo, Katherine R. Balka, Yamel Cardona Gloria, Vikram R. Rao, Eicke Latz, and Seth L. Masters

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Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus, Priyadharshini Devarajan, Michael C. Jones, Olivia Kugler-Umana, Allen M. Vong, Jingya Xia, and Susan L. Swain

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Total body CD4+ T cell dynamics in treated and untreated SIV infection revealed by in vivo imaging, Michele Di Mascio, Sharat Srinivasula, Insook Kim, Gorka Duralde, Alexis St. Claire, Paula DeGrange, Marisa St. Claire, Keith A. Reimann, Erin E. Gabriel, Jorge Carrasquillo, Richard C. Reba, Chang Paik, and Henry C. Lane

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The principles and practice of open fracture care, 2018, Amna Diwan, Kyle R. Eberlin, and Raymond Malcolm Smith

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Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans, Gregoriy A. Dokshin, Krishna S. Ghanta, Katherine M. Piscopo, and Craig C. Mello

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Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue, Laura T. Donlin, Ellen M. Gravallese, and Jennifer H. Anolik

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Upregulation of HLA-E by dengue and not Zika viruses, Elena Drews, Awadalkareem Adam, Phone Htoo, Elizabeth Townsley, and Anuja Mathew

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Complete and Durable Responses in Primary Central Nervous System Posttransplant Lymphoproliferative Disorder with Zidovudine, Ganciclovir, Rituximab, and Dexamethasone, James P. Dugan, Joyce D. Fingeroth, and Robert A. Baiocchi

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ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis, Mandy Dumortier, Franck Ladam, Isabelle Damour, Sophie Vacher, Ivan Bieche, Nathalie Marchand, Yvan de Launoit, David Tulasne, and Anne Chotteau-Lelievre

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Using virtual reality in medical education to teach empathy, Elizabeth Dyer, Barbara J. Swartzlander, and Marilyn R. Gugliucci

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Pre-diagnosis plasma immune markers and risk of non-Hodgkin lymphoma in two prospective cohort studies, Mara M. Epstein, Bernard Rosner, Elizabeth C. Breen, Julie L. Batista, Edward L. Giovannucci, Larry Magpantay, Jon C. Aster, Scott J. Rodig, Kimberly A. Bertrand, Francine Laden, Otoniel Martinez-Maza, and Brenda M. Birmann

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The wide utility of rabbits as models of human diseases, Pedro J. Esteves, Yuxing Chen, Shuying Liu, Shan Lu, Michael Vaine, Shixia Wang, and Rose Mage

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Comparing efficacy of lumen-apposing stents to plastic stents in the endoscopic management of mature peripancreatic fluid collections: a single-center experience, Matthew J. Fasullo, Yasir Al-Azzawai, Joan Kheder, Jeffrey Abergel, and Wahid Y. Wassef

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Hodgkin Lymphoma: Differences in Treatment Between Europe and the United States/North America: Evolving Trends in Protocol Therapy, Thomas J. Fitzgerald and Maryann Bishop-Jodoin

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Relationship Between Theory of Mind, Emotion Recognition, and Social Synchrony in Adolescents With and Without Autism, Paula Fitzpatrick, Jean A. Frazier, David E. Cochran, Teresa V. Mitchell, Caitlin Coleman, and R. C. Schmidt

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Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila, Pooja Flora, Sean Schowalter, SiuWah Wong-Deyrup, Matthew DeGennaro, Mohamad Ali Nasrallah, and Prashanth Rangan

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Poorly cytotoxic terminally differentiated CD56(neg)CD16(pos) NK cells accumulate in Kenyan children with Burkitt lymphomas, Catherine Forconi, Cormac P. Cosgrove, Pryia Saikumar-Lakshmi, Christina E. Nixon, Joslyn Foley, John Michael Ong'echa, Juliana A. Otieno, Galit Alter, Christian Munz, and Ann M. Moormann

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Metastatic Extramammary Paget's Disease: Pathogenesis and Novel Therapeutic Approach, Keitaro Fukuda and Takeru Funakoshi

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Rare gene fusion rearrangement SPTNB1-PDGFRB in an atypical myeloproliferative neoplasm, Vanessa Fiorini Furtado, Neeraj Y. Saini, William V. Walsh, Venu G. Bathini, and Patricia M. Miron

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Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers, Shaliu Fu, Qin Wang, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, Kaili Fan, Cuihua Gu, Cizhong Jiang, Ruixin Zhu, Anshul Kundaje, Aiping Lu, and Zhiping Weng

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Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers, Yu Fu, Pei-Hsuan Wu, Timothy J. Beane, Phillip D. Zamore, and Zhiping Weng

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Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers, Yu Fu, Pei-Hsuan Wu, Timothy J. Beane, Phillip D. Zamore, and Zhiping Weng

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The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology, Yu Fu, Yujing Yang, Han Zhang, Gwen Farley, Junling Wang, Kaycee A. Quarles, Zhiping Weng, and Phillip D. Zamore

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One Group's Historical Reflections on DNA Vaccine Development, Ellen F. Fynan, Shan Lu, and Harriet L. Robinson

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Congenital Heart Defects and Ciliopathies Associated With Renal Phenotypes, George C. Gabriel, Gregory J. Pazour, and Cecilia W. Lo

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Peptide Antigen Concentration Modulates Digital NFAT1 Activation in Primary Mouse Naive CD8(+) T Cells as Measured by Flow Cytometry of Isolated Cell Nuclei, Michael P. Gallagher, James M. Conley, and Leslie J. Berg

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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018, Lorenzo Galluzzi, Eric H. Baehrecke, Francis Ka-Ming Chan, and Guido Kroemer

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Excitatory motor neurons are local oscillators for backward locomotion, Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Taizo Kawano, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen

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The AGING Initiative experience: a call for sustained support for team science networks, Tullika Garg, Kathryn Anzuoni, Valentina Landyn, Alexandra Hajduk, Stephen Waring, Leah R. Hanson, and Heather E. Whitson

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Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish, Priyanjali Ghosh, Jennifer M. Maurer, and Charles G. Sagerstrom

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The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation, Nomeda A. Girnius, Yvonne J. K. Edwards, David S. Garlick, and Roger J. Davis

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Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis Against Enterotoxigenic Escherichia coli Infection, Serena Giuntini, Matteo Stoppato, Maja Sedic, Ejemel Monir, Jessica R. Pondish, Danielle Wisheart, Zachary Schiller, William D. Thomas Jr., Eileen M. Barry, Lisa Cavacini, mark S. klempner, and Yan Wang

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Therapeutic benefit of apremilast on enthesitis and dactylitis in patients with psoriatic arthritis: a pooled analysis of the PALACE 1-3 studies, Dafna D. Gladman, Arthur Kavanaugh, Juan J. Gomez-Reino, Jurgen Wollenhaupt, Maurizio Cutolo, Georg Schett, Eric Lespessailles, Benoit Guerette, Nikolay Delev, Lichen Teng, Christopher J. Edwards, Charles Birbara, and Philip J. Mease

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Optical Temperature Sensing With Infrared Excited Upconversion Nanoparticles, Kory Green, Kai Huang, Hai Pan, Gang Han, and Shuang Fang Lim

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Device Therapies Among Patients Receiving Primary Prevention Implantable Cardioverter-Defibrillators in the Cardiovascular Research Network, Robert T. Greenlee, Jerry H. Gurwitz, and David D. McManus

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Breathing New Life into Interstitial Lung Disease in Rheumatoid Arthritis, Peter K. Gregersen and Ellen M. Gravallese

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Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory, Alden L. Gross, Doug Tommet, Madeline D'Aquila, Eva Schmitt, Edward R. Marcantonio, Benjamin Helfand, Sharon K. Inouye, and Richard N. Jones

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Patterns of civilian and child deaths due to war-related violence in Syria: a comparative analysis from the Violation Documentation Center dataset, 2011-16, Debarati Guha-Sapir, Benjamin Schluter, Jose Manuel Rodriguez-Llanes, Louis Lillywhite, and Madelyn J. Hsiao-Rei Hicks

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Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis, Adilson L. Guilherme, David J. Pedersen, Felipe Henriques, Alexander H. Bedard, Elizabeth Henchey, Mark Kelly, Donald A. Morgan, Kamal Rahmouni, and Michael P. Czech

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A large-scale RNA interference screen identifies genes that regulate autophagy at different stages, Sujuan Guo, Kevin J. Pridham, Ching-Man A. Virbasius, Bin He, Liqing Zhang, Hanne Varmark, Michael R. Green, and Zhi Sheng

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Research evaluation support services in biomedical libraries, Karen Elizabeth Gutzman, Michael E. Bales, Christopher W. Belter, Thane Chambers, Liza Chan, Kristi L. Holmes, Ya-Ling Lu, Lisa A. Palmer, Rebecca Reznik-Zellen, Cathy C. Sarli, Amy M. Suiter, and Terrie R. Wheeler

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Determining the scope of attacks on health in four governorates of Syria in 2016: Results of a field surveillance program, Rohini J. Haar, Casey B. Risko, Sonal Singh, Diana Rayes, Ahmad Albaik, Mohammed Alnajar, Mazen Kewara, Emily Clouse, Elise Baker, and Leonard S. Rubenstein

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Video capsule endoscopy as a tool for evaluation of obscure overt gastrointestinal bleeding in the intensive care unit, Shahrad Hakimian, Salmaan Jawaid, Yurima Guilarte-Walker, Jomol Mathew, and David R. Cave

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The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation, Shahrad Hakimian, Yevgeniy Popov, Abbas Rupawala, Karen I. Salomon-Escoto, Steven Hatch, and Randall Pellish

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Suspected Blood Indicator to Identify Active Gastrointestinal Bleeding: A Prospective Validation, Samuel Han, Julien Fahed, and David R. Cave

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Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling, Anne Louise Hansen, Mona Motwani, Katherine A. Fitzgerald, and Christian K. Holm

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Effect of Anticitrullinated Protein Antibody Status on Response to Abatacept or Antitumor Necrosis Factor-alpha Therapy in Patients with Rheumatoid Arthritis: A US National Observational Study, Leslie R. Harrold, Heather J. Litman, Sean E. Connolly, Sheila Kelly, Winnie Hua, Evo Alemao, Lisa Rosenblatt, Sabrina Rebello, and Joel M. Kremer

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One-year risk of serious infection in patients treated with certolizumab pegol as compared with other TNF inhibitors in a real-world setting: data from a national U.S. rheumatoid arthritis registry, Leslie R. Harrold, Heather J. Litman, Katherine C. Saunders, Kimberly J. Dandreo, Bernice Gershenson, Jeffrey D. Greenberg, Robert Low, Jeffrey Stark, Robert Suruki, Srihari Jaganathan, Joel M. Kremer, and Mohamed Yassine

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Real-world Comparative Effectiveness of Tocilizumab Monotherapy vs. Tumor Necrosis Factor Inhibitors with Methotrexate in Patients with Rheumatoid Arthritis, Leslie R. Harrold, George W. Reed, Jennie Best, Steve Zlotnick, and Joel M. Kremer

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Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach to Care of US Patients With Rheumatoid Arthritis, Leslie R. Harrold, George W. Reed, Ani John, Christine J. Barr, Kevin Soe, Robert P. Magner, Katherine C. Saunders, Eric M. Ruderman, Tmirah Haselkorn, Jeffrey D. Greenberg, Allan Gibofsky, J. Timothy Harrington, and Joel M. Kremer

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Cystic fibrosis-related diabetes is caused by islet loss and inflammation, Nathaniel J. Hart, Jenny Aurielle B. Babon, Megan E. DeNicola, Sally C. Kent, and Alvin C. Powers

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Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission, Thomas Hart, Ngoc Thien Nguyen Thu, Nancy A. Nowak, Fuming Zhang, Robert J. Linhardt, Maria Diuk-Wasser, Sanjay Ram, Peter Kraiczy, and Yi-Pin Lin