Article Title
DOI Link
http://dx.doi.org/10.7191/neurol_bull.2013.1044
Publication Date
2014-02-18
Abstract
The use of brain magnetic resonance imaging (MRI) for evaluation of neurological disorders has increased in the past two decades. This has led to an increased detection of incidental findings on brain MRI. The most common of these asymptomatic abnormalities are white matter lesions that are interpreted as demyelinating based on radiological criteria. However, in the absence of associated clinical symptoms suggestive of multiple sclerosis (MS), a definite diagnosis of MS cannot be made in patients with these incidental white matter lesions. These patients are now diagnosed as radiologically isolated syndrome (RIS). The natural history and clinical approach to patients with RIS are reviewed in this article.
Keywords
radiologically isolated syndrome, multiple sclerosis, Barkhof criteria, incidental, white matter lesions
Rights and Permissions
© 2014 the Author(s). This open access article is distributed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License (https://creativecommons.org/licenses/by-nc-sa/3.0/).
Repository Citation
Leahy H, Garg N. Radiologically Isolated Syndrome: An Overview. Neurological Bulletin 2013;5:22-26. https://doi.org/10.7191/neurol_bull.2013.1044. Retrieved from https://escholarship.umassmed.edu/neurol_bull/vol5/iss1/5
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.