Article Title
DOI Link
http://dx.doi.org/10.7191/neurol_bull.2010.1020
Publication Date
December 2010
Abstract
Multiple sclerosis (MS) is an autoimmune disease of the central nerv-ous system characterized by inflammatory demyelination and some axonal damage. An overactive or dysfunctional immune response to self-antigen is believed to be the pathogenic mechanism and therefore the treatment of MS often involves immunosuppressive therapy. Be-cause of altered immune function in patients with MS, questions arise about risk of infections in this population and the safety and efficacy of common immunizations. The risk of MS exacerbation with common infections and safety and efficacy of immunization are reviewed along with the available guidelines for use of vaccines in patients with MS.
Keywords
multiple sclerosis, immunization, vaccine, immunosuppressive, relapse, influenza
Rights and Permissions
© 2010 the Author(s). This open access article is distributed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License (https://creativecommons.org/licenses/by-nc-sa/3.0/).
Repository Citation
Cahill JF, Izzo A, Garg N. Immunization in Patients With Multiple Sclerosis. Neurological Bulletin 2010;2:17-21. https://doi.org/10.7191/neurol_bull.2010.1020. Retrieved from https://escholarship.umassmed.edu/neurol_bull/vol2/iss1/4
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.