Abstract
Multiple sclerosis (MS) is an autoimmune disease of the central nerv-ous system characterized by inflammatory demyelination and some axonal damage. An overactive or dysfunctional immune response to self-antigen is believed to be the pathogenic mechanism and therefore the treatment of MS often involves immunosuppressive therapy. Be-cause of altered immune function in patients with MS, questions arise about risk of infections in this population and the safety and efficacy of common immunizations. The risk of MS exacerbation with common infections and safety and efficacy of immunization are reviewed along with the available guidelines for use of vaccines in patients with MS.DOI
10.7191/neurol_bull.2010.1020Permanent Link to this Item
http://hdl.handle.net/20.500.14038/38077Rights
© 2010 the Author(s). This open access article is distributed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License (https://creativecommons.org/licenses/by-nc-sa/3.0/).Distribution License
http://creativecommons.org/licenses/by-nc-sa/3.0/ae974a485f413a2113503eed53cd6c53
10.7191/neurol_bull.2010.1020
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Except where otherwise noted, this item's license is described as © 2010 the Author(s). This open access article is distributed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License (https://creativecommons.org/licenses/by-nc-sa/3.0/).