This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Department of Neurology.

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Publications from 2015

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Integrating Neuroscience Knowledge and Neuropsychiatric Skills Into Psychiatry: The Way Forward, Barbara Schildkrout, Sheldon Benjamin, and Margo D. Lauterbach

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Effects of Recent Concussion on Brain Bioenergetics: A Phosphorus-31 Magnetic Resonance Spectroscopy Study, Elif M. Sikoglu, Ana A. Liso Navarro, Suzanne M. Czerniak, Joseph McCafferty, Jordan Eisenstock, J. Herbert Stevenson, Jean A. King, and Constance M. Moore

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Disrupted seasonal biology impacts health, food security and ecosystems, T. J. Stevenson, M. E. Visser, W. Arnold, P. Barrett, S. Biello, A. Dawson, D. L. Denlinger, D. Dominoni, F. J. Ebling, S. Elton, and William J. Schwartz

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Bilateral Intracranial Vertebral Artery Stenosis Presenting as Recurrent Prolonged Presyncopal Episodes, Banu Sundar, Majaz Moonis, Ajay K. Wakhloo, and Ajit S. Puri

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Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS, Helene Tran, Sandra Almeida, Jill Moore, Tania F. Gendron, UmaDevi Chalasani, Yubing Lu, Xing Du, Jeffrey A. Nickerson, Leonard Petrucelli, Zhiping Weng, and Fen-Biao Gao

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Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke, Anya Turetsky, Richard P. Goddeau, and Nils Henninger

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FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions, Dejun Yang, Abbas Abdallah, Zhaodong Li, Yubing Lu, Sandra Almeida, and Fen-Biao Gao

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Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila, Yeliz Yuva-Aydemir, Xia-Lian Xu, Ozkan Aydemir, Eduardo Gascon, Serkan Sayin, Wenke Zhou, Yang Hong, and Fen-Biao Gao

Publications from 2014

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Amyotrophic lateral sclerosis: analysis of ALS cases in a predominantly admixed population of Ecuador, Miriam Bucheli, Andres Andino, Mayra Montalvo, Jose Cruz, Nazem Atassi, James Berry, and Johnny Salameh

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Switching neuronal state: optimal stimuli revealed using a stochastically-seeded gradient algorithm, Joshua TsuKang Chang and David Paydarfar

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Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors, Itzel Escobedo-Avila, Fernanda Vargas-Romero, Anayansi Molina-Hernandez, Rodrigo Lopez-Gonzalez, Daniel Cortes, Juan A. De Carlos, and Ivan Velasco

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Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons, Claudia Fallini, Jeremy P. Rouanet, Paul G. Donlin-Asp, Peng Guo, Honglai Zhang, Robert H. Singer, Wilfried Rossoll, and Gary J. Bassell

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Severe leukoaraiosis portends a poor outcome after traumatic brain injury, Nils Henninger, Saef Izzy, Raphael A. Carandang, Wiley R. Hall, and Susanne Muehlschlegel

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Leukoaraiosis predicts cortical infarct volume after distal middle cerebral artery occlusion, Nils Henninger, Muhib Khan, Jiaying Zhang, Majaz Moonis, and Richard P. Goddeau

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Predictors of Outcome following Stroke due to Isolated M2 Occlusions, Muhib Khan, Richard P. Goddeau, Jayne Zhang, Majaz Moonis, and Nils Henninger

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Clot injection technique affects thrombolytic efficacy in a rat embolic stroke model: implications for translaboratory collaborations, Marilena Marinescu, James P. Bouley, Juyu Chueh, Marc Fisher, and Nils Henninger

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Leucine-rich glioma-inactivated protein 1 antibody encephalitis: A case report, Yunis M. Mayasi, Deepak Takhtani, and Neeta Garg

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Pre and Post-stroke Use of Statins Improves Stroke Outcome, Majaz Moonis, Rajat Kumar, Nils Henninger, Kevin Kane, and Marc Fisher

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Dantrolene for cerebral vasospasm after subarachnoid haemorrhage: a randomised double blind placebo-controlled safety trial, Susanne Muehlschlegel, Raphael A. Carandang, Wiley R. Hall, Nisha Kini, Saef Izzy, Bridget Garland, Cynthia Ouillette, Imramsjah M. J. van der Bom, Thomas F. Flood, Matthew J. Gounis, John P. Weaver, Bruce A. Barton, and Ajay K. Wakhloo

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The Role of Multiple Sclerosis as a Risk Factor for the Development of Osteoporosis, Christopher Perrone, Christine M. Foley, Linda C. Churchill, Sybil L. Crawford, Judith K. Ockene, and Carolina Ionete

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Functions of FUS/TLS from DNA repair to stress response: implications for ALS, Reddy Ranjith Kumar Sama, Catherine L. Ward, and Daryl A. Bosco

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Enhancement in cognitive function recovery by granulocyte-colony stimulating factor in a rodent model of traumatic brain injury, Elif M. Sikoglu, Meghan E. Heffernan, Kelly Tam, Kenneth M. Sicard, Bernt T. Bratane, Meina Quan, Marc Fisher, and Jean A. King

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Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis, Hongyan Wang, Bin Yang, Linghua Qiu, Chunxing Yang, Joshua Kramer, Qin Su, Yansu Guo, Robert H. Brown Jr., Guangping Gao, and Zuoshang Xu

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Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10, Bin Yang, Shaoyong Li, Hongyan Wang, Yansu Guo, Dominic J. Gessler, Chunyan Cao, Qin Su, Joshua Kramer, Li Zhong, Seemin Seher Ahmed, Hongwei Zhang, Ran He, Ronald C. Desrosiers, Robert H. Brown Jr., Zuoshang Xu, and Guangping Gao

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Leukoaraiosis predicts a poor 90-day outcome after endovascular stroke therapy, Jingyan Zhang, Ajit S. Puri, Muhammad A. Khan, Richard P. Goddeau Jr, and Nils Henninger

Publications from 2013

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Intracranial hypotension with multiple complications: an unusual case report, Swetha Ade and Majaz Moonis

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Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons, Sandra Almeida, Eduardo Gascon, Helene Tran, Hsin-Jung Chou, Tania F. Gendron, Steven Degroot, Andrew R. Tapper, Chantal Sellier, Nicolas Charlet-Berguerand, Anna Karydas, William W. Seeley, Adam L. Boxer, Leonard Petrucelli, Bruce L. Miller, and Fen-Biao Gao

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Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage, Jared R. Auclair, Joshua L. Johnson, Qian Liu, Joseph P. Salisbury, Melissa S. Rotunno, Gregory A. Petsko, Dagmar Ringe, Robert H. Brown Jr., Daryl A. Bosco, and Jeffrey N. Agar

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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics, Desiree M. Baron, Laura J. Kaushansky, Catherine L. Ward, Reddy Ranjith Kumar Sama, Ru-ju Chian, Kristin J. Boggio, Alexandre J. C. Quaresma, Jeffrey A. Nickerson, and Daryl A. Bosco

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Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells, K. Bienemann, M. S. Staege, S. J. Howe, Miguel Sena-Esteves, H. Hanenberg, and C. M. Kramm

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Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1, Teresa J. Broering, Hongyan Wang, Naomi K. Boatright, Yang Wang, Katherine Baptista, Gilda Shayan, Kerry A. Garrity, Can Kayatekin, Daryl A. Bosco, C. Robert Matthews, Donna M. Ambrosino, Zuoshang Xu, and Gregory J. Babcock

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A rare presentation of hypertrophic olivary degeneration secondary to primary central nervous system lymphoma, David Cachia, Saef Izzy, Thomas W. Smith, and Carolina Ionete

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Post-Traumatic Cerebral Edema, Raphael A. Carandang

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Central respiratory failure during acute organophosphate poisoning, Jennifer L. Carey, Courtney Dunn, and Romolo J. Gaspari

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Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing, Jeroen de Vrij, Sybren L.N. Maas, Malisa van Nispen, Miguel Sena-Esteves, Ronald W.A. Limpens, Abraham J. Koster, Sieger Leenstra, Martine L. Lamfers, and Marike L. Broekman D

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The spectrum of translational stroke research, Marc Fisher

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Heart rate is a prognostic risk factor for myocardial infarction: a post hoc analysis in the PERFORM (Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack) study population, Kim Fox, Marie-Germaine Bousser, Pierre Amarenco, Angel Chamorro, Marc Fisher, Ian Ford, Michael G. Hennerici, Heinrich P. Mattle, and Peter M. Rothwell

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Gender differences of mental health consumers accessing integrated primary and behavioral care, Hillary Gleason, Marie Hobart, Leah Bradley, John Landers, Sarah Langenfeld, Makenzie E. Tonelli, and Monika E. Kolodziej

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Headache in stroke: a review, Richard P. Goddeau and Adel Alhazzani

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Multi-modal approach for investigating brain and behavior changes in an animal model of traumatic brain injury, Meghan E. Heffernan, Wei Huang, Kenneth M. Sicard, Bernt T. Bratane, Nanyin Zhang, Marc Fisher, Jean A. King, and Elif M. Sikoglu

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Rodent Traumatic Brain Injury as a Model for Human Traumatic Axonal Damage and Neurodegeneration, Nils Henninger

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QTc-prolongation in posterior circulation stroke, Nils Henninger, Diogo C. Haussen, Nikolaos Kakouros, Magdy Selim, D. Eric Searls, Sandeep Kumar, Gottfried Schlaug, and Louis R. Caplan

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Leukoaraiosis and sex predict the hyperacute ischemic core volume, Nils Henninger, Eugene Lin, Diogo C. Haussen, Laura L. Lehman, Deepak Takhtani, Magdy Selim, and Majaz Moonis

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Point process modeling of interbreath interval: a new approach for the assessment of instability of breathing in neonates, Premananda Indic, David Paydarfar, and Riccardo Barbieri

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BRAIN TOPiC Study: Assessing Variability in Traumatic Brain Injury (TBI) Outcome Prognostication – Do Self-Fulfilling Prophecies Exist in TBI, Too?, Saef Izzy, Rebecca Compton, Raphael A. Carandang, Wiley R. Hall, and Susanne Muehlschlegel

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Molecular Mechanisms of FSH Muscular Dystrophy Pathogenesis, Peter L. Jones and Takako I. Jones

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The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila, Zhaodong Li, Yubing Lu, Xia-Lian Xu, and Fen-Biao Gao

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Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation, Yubing Lu, Zhijun Zhang, Danqiong Sun, Sean T. Sweeney, and Fen-Biao Gao

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Improving the Outcome Prognostication of Critically Ill Patients with Moderate-Severe TBI, Susanne Muehlschlegel

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Frequency and impact of intensive care unit complications on moderate-severe traumatic brain injury: early results of the Outcome Prognostication in Traumatic Brain Injury (OPTIMISM) Study, Susanne Muehlschlegel, Raphael A. Carandang, Cynthia Ouillette, Wiley R. Hall, Frederick A. Anderson Jr., and Robert J. Goldberg

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Frequency and Impact of Intensive Care Unit Complications on Moderate-Severe Traumatic Brain Injury – Early Results of the Outcome Prognostication in Traumatic Brain Injury (OPTIMISM) Study, Susanne Muehlschlegel, Raphael A. Carandang, Cynthia Ouillette, Wiley R. Hall, Frederick Anderson, and Robert J. Goldberg

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Traumatic Brain Injury: Translation from Animal Models and Genetics to Improving Outcomes, Susanne Muehlschlegel, Nils Henninger, Raphael A. Carandang, and Constance M. Moore

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Differentiating reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage from other causes of subarachnoid hemorrhage, Susanne Muehlschlegel, Oguzhan Kursun, Mehmet A. Topcuoglu, Joshua Fok, and Aneesh B. Singhal

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Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1, Sarah Pickles, Laurie Destroismaisons, Sarah L. Peyrard, Sarah Cadot, Guy A. Rouleau, Robert H. Brown Jr., Jean-Pierre Julien, Nathalie Arbour, and Christine Vande Velde

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Deep brain stimulation, Andrzej W. Przybyszewski

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Granulocyte colony-stimulating factor in patients with acute ischemic stroke: results of the AX200 for Ischemic Stroke trial, E. Bernd Ringelstein, Vincent Thijs, Bo Norrving, Angel Chamorro, Franz Aichner, Martin Grond, Jeff Saver, Rico Laage, Armin Schneider, Frank Rathgeb, Gerhard Vogt, Gabriele Charisse, Jochen B. Fiebach, Stefan Schwab, Wolf R. Schabitz, Rainer Kollmar, Marc Fisher, Miroslav Brozman, David Skoloudik, Franz Gruber, Joaquin Serena Leal, Roland Veltkamp, Martin Kohrmann, and Jorg Berrouschot

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Phosphoglycerate mutase deficiency with tubular aggregates in a patient from Panama, Johnny Salameh, Namita Goyal, Rabia Choudry, Sandra Camelo-Piragua, and Peter Siao Tick Chong

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Focal absence of diffusion tensor tracts from primary motor cortex in primary lateral sclerosis, Johnny S. Salameh, N. Patel, Shaokuan Zheng, and Keith A. Cauley

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FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress, Reddy Ranjith R. Sama, Catherine Ward, Laura J. Kaushansky, Nathan Lemay, Shinsuke Ishigaki, Fumihiko Urano, and Daryl A. Bosco

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Stroke journal: what is being published to advance the field, Gustavo Saposnik, S. Claiborne Johnston, Stavroula Raptis, Bruce Ovbiagele, Marc Fisher, and Stroke Journal Editorial Board

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Amyotrophic lateral sclerosis: Problems and prospects, Jemeen Sreedharan and Robert H. Brown Jr.

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Gene transfer to the CNS using recombinant adeno-associated virus, Lorelei Stoica, Seemin Seher Ahmed, Guangping Gao, and Miguel Sena-Esteves

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Characterization of FUS mutations in amyotrophic lateral sclerosis using RNA-Seq, Marka van Blitterswijk, Eric T. Wang, Brad A. Friedman, Pamela J. Keagle, Ashley Lyn Leclerc, Leonard H. van den Berg, David E. Housman, Jan H. Veldink, John E. Landers, and Patrick Lowe

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Finding the striatum in sheep: use of a multi-modal guided approach for convection enhanced delivery, I. M. J. van der Bom, Richard P. Moser, Guangping Gao, Erica Mondo, Denice O'Connell, Matthew J. Gounis, Sarah McGowan, J. Chaurette, N. Bishop, Miguel Sena-Esteves, Christian Mueller, and Neil Aronin

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Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations, Zhijun Zhang, Sandra Almeida, Yubing Lu, Agnes L. Nishimura, Lingtao Peng, Danqiong Sun, Bei Wu, Anna M. Karydas, Maria C. Tartaglia, Jamie C. Fong, Bruce L. Miller, Robert V. Farese Jr., Melissa J. Moore, Christopher E. Shaw, and Fen-Biao Gao

Publications from 2012

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Can a detailed neurological exam improve prediction of extubation success in neurocritically ill patients?, Sanam Baghshomali, Nathanael Slater, Raphael A. Carandang, Cynthia Ouillette, Wiley R. Hall, and Susanne Muehlschlegel

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Limbic and motor function comparison of deep brain stimulation of the zona incerta and subthalamic nucleus, Anthony M. Burrows, Paula D. Ravin, Peter Novak, Mary Linton Peters, Brian Dessureau, Joan M. Swearer, and Julie G. Pilitsis

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Genetic determinants of cerebral edema in severe traumatic brain injury: A pilot study of the role of CACNA1 and AQP4 gene mutations, Raphael A. Carandang, Susanne Muehlschlegel, Wiley R. Hall, Cynthia Ouillette, and Robert H. Brown Jr.

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International, multicenter randomized preclinical trials in translational stroke research: it's time to act, Ulrich Dirnagl and Marc Fisher

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Endovascular acute ischemic stroke therapy: applying basic science to clinical decisions, Marc Fisher

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Identifying and utilizing the ischemic penumbra, Marc Fisher and Birgul Bastan

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Neuroprotective effects of statins: evidence from preclinical and clinical studies, Marc Fisher and Majaz Moonis

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RNA-binding proteins in neurological disease, Fen-Biao Gao and J. Paul Taylor

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Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration, Eduardo Gascon and Fen-Biao Gao

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Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS, Paloma Gonzalez-Perez, Yubing Lu, Ru-ju Chian, Peter Sapp, Rudolph E. Tanzi, Lars Bertram, Diane McKenna-Yasek, Fen-Biao Gao, and Robert H. Brown Jr.

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Homologous Recombination Mediates Functional Recovery of Dysferlin Deficiency following AAV5 Gene Transfer, William E. Grose, K. Reed Clark, Danielle Griffin, Vinod Malik, Kimberly M. Shontz, Chrystal L. Montgomery, Sarah Lewis, Robert H. Brown Jr., Paul M. L. Janssen, Jerry R. Mendell, and Louise R. Rodino-Klapac

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Leukoaraiosis predicts poor 90-day outcome after acute large cerebral artery occlusion, Nils Henninger, Eugene Lin, Stephen P. Baker, Ajay K. Wakhloo, Deepak Takhtani, and Majaz Moonis

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Multi-scale motility amplitude associated with suicidal thoughts in major depression, Premananda Indic, Greg Murray, Carlo Maggini, Mario Amore, Tiziana Meschi, Loris Borghi, Ross J. Baldessarini, and Paola Salvatore

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Occult cervical spinal dural arteriovenous fistula masquerading as acute spinal cord ischemia, Saef Izzy, Bilal Hameed, Chutima Saipetch, Eugene Lin, and David Paydarfar

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A call for transparent reporting to optimize the predictive value of preclinical research, Story C. Landis and Marc Fisher

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Neuronal Functions of ESCRTs, Jin-A Lee and Fen-Biao Gao

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Impact of medical and neurological ICU complications on moderate-severe traumatic brain injury (TBI), Susanne Muehlschlegel, Raphael A. Carandang, Cynthia Ouillette, Wiley R. Hall, Frederick A. Anderson Jr., and Robert J. Goldberg

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Incidence rates of ICU complications in moderate-severe traumatic brain injury (TBI), Susanne Muehlschlegel, Raphael A. Carandang, Cynthia Ouillette, Wiley R. Hall, Frederick A. Anderson Jr., and Robert J. Goldberg

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Production and discovery of novel recombinant adeno-associated viral vectors, Christian Mueller, Li Zhong, Dmitry Ratner, Miguel Sena-Esteves, and Guangping Gao

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Treatment of multiple system atrophy using intravenous immunoglobulin, Peter Novak, Arlene Williams, Paula D. Ravin, Omar Zurkiya, Amir Abduljalil, and Vera Novak

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dSarm/Sarm1 is required for activation of an injury-induced axon death pathway, Jeannette M. Osterloh, Jing Yang, Timothy M. Rooney, A. Nicole Fox, Robert Adalbert, Eric H. Powell, Amy E. Sheehan, Michelle A. Avery, Rachel Hackett, Mary A. Logan, Jennifer M. MacDonald, Jennifer S. Ziegenfuss, Stefan Milde, Ying-Ju Hou, Carl Nathan, Aihao Ding, Robert H. Brown Jr., Laura Comforti, Michael Coleman, Marc Tessier-Lavigne, Stephan Zuchner, and Marc R. Freeman

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Serum sodium values and their association with adverse outcomes in moderate-severe traumatic brain injury (TBI), Lucia Rivera Lara, Susanne Muehlschlegel, Raphael A. Carandang, Cynthia Ouillette, Wiley R. Hall, Frederick A. Anderson Jr., and Robert J. Goldberg

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Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants, Kailiang Sun, Jakub Orzechowski Westholm, Kazuya Tsurudome, Joshua W Hagen, Yubing Lu, Minoree Kohwi, Doron Betel, Fen-Biao Gao, A. Pejmun Haghighi, Chris Q. Doe, and Eric C. Lai

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Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis, Chi-Hong Wu, Pamela J. Keagle, Peter Sapp, Katarzyna Piotrowska, Patrick Lowe, Diane McKenna-Yasek, Desiree Baron, Jason E. Kost, Paloma Gonzalez-Perez, Andrew D. Fox, Jenni Adams, Ashley Lyn Leclerc, Melissa J. Moore, Jill A. Zitzewitz, Zuoshang Xu, Daryl Bosco, Robert H. Brown Jr., and John E. Landers

Publications from 2011

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Improving the accuracy of perfusion imaging in acute ischemic stroke, Gregory W. Albers and Marc Fisher

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Progranulin, a glycoprotein deficient in frontotemporal dementia, is a novel substrate of several protein disulfide isomerase family proteins, Sandra Almeida, Lijuan Zhou, and Fen-Biao Gao

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Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial, Marie-Germaine Bousser, Pierre Amarenco, Angel Chamorro, Marc Fisher, Ian Ford, Kim M. Fox, Michael G. Hennerici, Heinrich P. Mattle, Peter M. Rothwell, Agnes de Cordoue, and Marie-Dominique Fratacci

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Neuroprotection by freezing ischemic penumbra evolution without cerebral blood flow augmentation with a postsynaptic density-95 protein inhibitor, Bernt T. Bratane, Hong Cui, Douglas J. Cook, James P. Bouley, Michael Tymianski, and Marc Fisher

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Nicotine replacement therapy after subarachnoid hemorrhage is not associated with increased vasospasm, Raphael A. Carandang, Bruce A. Barton, Guy A. Rordorf, Christopher S. Ogilvy, and John R. Sims

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Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia, Basar Cenik, Chantelle F. Sephton, Colleen M. Dewey, Xunde Xian, Shuguang Wei, Kimberley Yu, Wenze Niu, Giovanni Coppola, Sarah E. Coughlin, Suzee E. Lee, Daniel R. Dries, Sandra Almeida, Daniel H. Geschwind, Fen-Biao Gao, Bruce L. Miller, Robert V. Farese Jr., Bruce A. Posner, Gang Yu, and Joachim Herz

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Non-psychiatric health problems among psychiatric inpatients with intellectual disabilities, Lauren Charlot, Susan L. Abend, Paula D. Ravin, Mastis Kimberly, Anne T. Hunt, and Curtis K. Deutsch

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New approaches to neuroprotective drug development, Marc Fisher

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The perils of combination antithrombotic therapy and potential resolutions, Marc Fisher and Joseph Loscalzo

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The perils of combination antithrombotic therapy and potential resolutions, Marc Fisher and Joseph Loscalzo

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Scaling behavior of human locomotor activity amplitude: association with bipolar disorder, Premananda Indic, Paola Salvatore, Carlo Maggini, Stefano Ghidini, Gabriella Ferraro, Ross J. Baldessarini, and Greg Murray