Title
Acute ischemic stroke therapy. A clinical overview
UMMS Affiliation
Department of Neurology
Publication Date
1997-1
Document Type
Article
Subjects
Acute Disease; Brain Ischemia; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Humans; Neuroprotective Agents; Thrombolytic Therapy; Time Factors
Disciplines
Nervous System Diseases | Neurology
Abstract
Acute ischemic stroke therapy has two basic therapies, dissolving the intravascular occlusion by thrombolytic therapy and protecting the brain from the harmfull cellular, and metabolic consequences ofischemic injury by neuroprotective therapy. It seems most likely that the methods that will be used to treat the acute ischemic stroke patient will be multiple, likely a combination of thrombolytic therapy for early reperfusion and neuroprotective therapy for maintaining vitality. In the last decade, a number of advances in the field of imaging and pharmacology have been made which should provide meaningful improvement for the management of acute ischemic stroke patients in the near future. This update summarizes recent clinical trials and emphasizes the question of risk versus benefit for the acute ischemic stroke therapies being developed.
Source
Eur Neurol. 1997;38(3):141-54.
Journal/Book/Conference Title
European neurology
Related Resources
PubMed ID
9363826
Repository Citation
Onal MZ, Fisher M. (1997). Acute ischemic stroke therapy. A clinical overview. Neurology Publications. Retrieved from https://escholarship.umassmed.edu/neuro_pp/85