Title

Marker proteins of platelet activation in patients with cerebrovascular disease

UMMS Affiliation

Department of Neurology

Publication Date

1982-11-01

Document Type

Article

Subjects

Adolescent; Adult; Aged; Beta-Globulins; Blood Coagulation Factors; Blood Platelets; Cerebrovascular Disorders; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Factor 4; beta-Thromboglobulin

Disciplines

Nervous System Diseases | Neurology

Abstract

Platelet activation is assumed to occur in many patients with strokes of transient ischemic attacks (TIAs). Determination of this activity can now be measured by assaying the platelet-specific proteins, platelet factor 4 and beta-thromboglobulin. These proteins are platelet specific and are released during irreversible aggregation. The plasma level of these proteins was measured in patients with strokes and TIAs and both groups had significantly greater values than healthy control subjects. These markers of platelet activation may provide further understanding of the role of platelets in the etiology, diagnosis, and treatment of cerebrovascular disease.

Source

Arch Neurol. 1982 Nov;39(11):692-5.

Journal/Book/Conference Title

Archives of neurology

Related Resources

Link to article in PubMed

PubMed ID

6181767

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