Title

Extending the Time Window for Endovascular and Pharmacological Reperfusion

UMMS Affiliation

Department of Neurology

Publication Date

2016-01-07

Document Type

Article

Disciplines

Nervous System Diseases | Neurology

Abstract

Pharmacological and device-induced reperfusion therapies have demonstrated increasingly positive outcomes regarding both reperfusion efficacy and 90-day functional outcomes after acute ischemic stroke. However, presently, only a minority of patients are eligible for these treatments. Less than 10 % of all ischemic stroke patients receive intravenous thrombolysis in most centers and it has been projected that only approximately 7-15 % of ischemic stroke patients are eligible for acute endovascular intervention. Making these effective therapies safely available to a much larger number of patients is critical for expanding the benefits of acute ischemic stroke treatment. In this article, we summarize the key results from the clinical trials, challenges, and exciting novel opportunities to increase patient eligibility for these therapies as well as for better outcomes for stroke patients.

DOI of Published Version

10.1007/s12975-015-0444-4

Source

Transl Stroke Res. 2016 Jan 7. Link to article on publisher's site

Journal/Book/Conference Title

Translational stroke research

Comments

First author Nils Henninger is a doctoral student in the Millennium PhD Program (MPP) in the Graduate School of Biomedical Sciences (GSBS) at UMass Medical School.

Related Resources

Link to Article in PubMed

PubMed ID

26739964

Link to Full Text

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