Title
Extending the Time Window for Endovascular and Pharmacological Reperfusion
UMMS Affiliation
Department of Neurology
Publication Date
2016-01-07
Document Type
Article
Disciplines
Nervous System Diseases | Neurology
Abstract
Pharmacological and device-induced reperfusion therapies have demonstrated increasingly positive outcomes regarding both reperfusion efficacy and 90-day functional outcomes after acute ischemic stroke. However, presently, only a minority of patients are eligible for these treatments. Less than 10 % of all ischemic stroke patients receive intravenous thrombolysis in most centers and it has been projected that only approximately 7-15 % of ischemic stroke patients are eligible for acute endovascular intervention. Making these effective therapies safely available to a much larger number of patients is critical for expanding the benefits of acute ischemic stroke treatment. In this article, we summarize the key results from the clinical trials, challenges, and exciting novel opportunities to increase patient eligibility for these therapies as well as for better outcomes for stroke patients.
DOI of Published Version
10.1007/s12975-015-0444-4
Source
Transl Stroke Res. 2016 Jan 7. Link to article on publisher's site
Journal/Book/Conference Title
Translational stroke research
Related Resources
PubMed ID
26739964
Repository Citation
Henninger N, Fisher M. (2016). Extending the Time Window for Endovascular and Pharmacological Reperfusion. Neurology Publications. https://doi.org/10.1007/s12975-015-0444-4. Retrieved from https://escholarship.umassmed.edu/neuro_pp/427
Comments
First author Nils Henninger is a doctoral student in the Millennium PhD Program (MPP) in the Graduate School of Biomedical Sciences (GSBS) at UMass Medical School.