International, multicenter randomized preclinical trials in translational stroke research: it's time to act
Department of Neurology
Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; *Stroke; *Translational Medical Research
Nervous System Diseases | Neurology
Translational stroke research is in a crisis, and pharmaceutical companies continue to exit the field. Many reasons for the apparently insurmountable barrier between the bench and bedside in stroke drug development have been identified. It is time to act now to bridge the gap between preclinical and clinical studies of purported new therapies. We strongly believe that it is too early to abandon translational stroke research.
DOI of Published Version
J Cereb Blood Flow Metab. 2012 Jun;32(6):933-5. doi: 10.1038/jcbfm.2012.51. Link to article on publisher's site
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Dirnagl, Ulrich and Fisher, Marc, "International, multicenter randomized preclinical trials in translational stroke research: it's time to act" (2012). Neurology Publications and Presentations. 423.