Title

International, multicenter randomized preclinical trials in translational stroke research: it's time to act

UMMS Affiliation

Department of Neurology

Publication Date

2012-06-01

Document Type

Editorial

Subjects

Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; *Stroke; *Translational Medical Research

Disciplines

Nervous System Diseases | Neurology

Abstract

Translational stroke research is in a crisis, and pharmaceutical companies continue to exit the field. Many reasons for the apparently insurmountable barrier between the bench and bedside in stroke drug development have been identified. It is time to act now to bridge the gap between preclinical and clinical studies of purported new therapies. We strongly believe that it is too early to abandon translational stroke research.

DOI of Published Version

10.1038/jcbfm.2012.51

Source

J Cereb Blood Flow Metab. 2012 Jun;32(6):933-5. doi: 10.1038/jcbfm.2012.51. Link to article on publisher's site

Journal/Book/Conference Title

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Comments

Republished in: Stroke. 2012 Jun;43(6):1453-4. doi: 10.1161/STROKEAHA.112.653709.

Related Resources

Link to Article in PubMed

PubMed ID

22510602

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