UMMS Affiliation

Department of Neurology

Publication Date


Document Type



Animals; Publishing; Random Allocation; Research Design; Sample Size; Statistics as Topic


Laboratory and Basic Science Research | Neurology | Statistics and Probability


The US National Institute of Neurological Disorders and Stroke convened major stakeholders in June 2012 to discuss how to improve the methodological reporting of animal studies in grant applications and publications. The main workshop recommendation is that at a minimum studies should report on sample-size estimation, whether and how animals were randomized, whether investigators were blind to the treatment, and the handling of data. We recognize that achieving a meaningful improvement in the quality of reporting will require a concerted effort by investigators, reviewers, funding agencies and journal editors. Requiring better reporting of animal studies will raise awareness of the importance of rigorous study design to accelerate scientific progress.

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DOI of Published Version



Nature. 2012 Oct 11;490(7419):187-91. doi: 10.1038/nature11556. Link to article on publisher's site

Journal/Book/Conference Title



Full author list omitted for brevity. For the full list of authors, see article.

Related Resources

Link to Article in PubMed

PubMed ID




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