Department of Neurology
Animals; Publishing; Random Allocation; Research Design; Sample Size; Statistics as Topic
Laboratory and Basic Science Research | Neurology | Statistics and Probability
The US National Institute of Neurological Disorders and Stroke convened major stakeholders in June 2012 to discuss how to improve the methodological reporting of animal studies in grant applications and publications. The main workshop recommendation is that at a minimum studies should report on sample-size estimation, whether and how animals were randomized, whether investigators were blind to the treatment, and the handling of data. We recognize that achieving a meaningful improvement in the quality of reporting will require a concerted effort by investigators, reviewers, funding agencies and journal editors. Requiring better reporting of animal studies will raise awareness of the importance of rigorous study design to accelerate scientific progress.
Rights and Permissions
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/.
DOI of Published Version
Nature. 2012 Oct 11;490(7419):187-91. doi: 10.1038/nature11556. Link to article on publisher's site
Landis, Story C. and Fisher, Marc, "A call for transparent reporting to optimize the predictive value of preclinical research" (2012). Neurology Publications and Presentations. 419.