Tumor-associated aphasia in left hemisphere primary brain tumors: the importance of age and tumor grade
Department of Neurology
Adult; Aged; Aged, 80 and over; Aging; Aphasia; Brain Neoplasms; Female; Humans; Language Disorders; Male; Middle Aged
Neurology | Neuroscience and Neurobiology
Although one-quarter of patients with primary brain tumors have language disturbances at the time of initial presentation, the factors contributing to their aphasia are not clear. A group of 32 patients with primary tumors of the left hemisphere was collected retrospectively and the relationship between clinical, radiographic, and pathologic factors and tumor-associated aphasia was examined. We assessed language function before beginning any treatment including steroids. The factor that best predicted language disturbance was greater patient age; the only other significant factor was tumor grade. Tumor size made a nearly significant impact, but tumor location within the left hemisphere did not correlate with aphasia.
Neurology. 1989 Jan;39(1):48-50.
Recht, Lawrence D.; McCarthy, K.; O'Donnell, Brian F.; Cohen, R.; and Drachman, David A., "Tumor-associated aphasia in left hemisphere primary brain tumors: the importance of age and tumor grade" (1989). Neurology Publications and Presentations. 258.