Tumor-associated aphasia in left hemisphere primary brain tumors: the importance of age and tumor grade
Department of Neurology
Adult; Aged; Aged, 80 and over; Aging; Aphasia; Brain Neoplasms; Female; Humans; Language Disorders; Male; Middle Aged
Neurology | Neuroscience and Neurobiology
Although one-quarter of patients with primary brain tumors have language disturbances at the time of initial presentation, the factors contributing to their aphasia are not clear. A group of 32 patients with primary tumors of the left hemisphere was collected retrospectively and the relationship between clinical, radiographic, and pathologic factors and tumor-associated aphasia was examined. We assessed language function before beginning any treatment including steroids. The factor that best predicted language disturbance was greater patient age; the only other significant factor was tumor grade. Tumor size made a nearly significant impact, but tumor location within the left hemisphere did not correlate with aphasia.
Neurology. 1989 Jan;39(1):48-50.
Recht LD, McCarthy K, O'Donnell BF, Cohen R, Drachman DA. (1989). Tumor-associated aphasia in left hemisphere primary brain tumors: the importance of age and tumor grade. Neurology Publications. Retrieved from https://escholarship.umassmed.edu/neuro_pp/258