Title

Novel drug delivery systems: opportunities and caveats

UMMS Affiliation

Department of Neurology

Publication Date

1989-09-01

Document Type

Article

Subjects

Alzheimer Disease; Brain Diseases; Humans; *Infusion Pumps; Nerve Tissue

Disciplines

Neurology | Neuroscience and Neurobiology

Abstract

Programmed infusion pumps, polymers and neural transplants provide the capability of delivering a variety of agents to specific locations in the central nervous system. If a necessary or therapeutically useful substance cannot otherwise penetrate the blood-brain barrier, or must be delivered to a precise location in the CNS, these strategies may be of value in neurologic disease. The possibility of transplanting functioning tissue into the brain raises the hope of providing "new parts for old." For drugs that can penetrate the blood-brain barrier, and do not require a single precise anatomic site of action, systemic administration remains the "gold standard." The role of these novel drug delivery systems in treatment of Alzheimer's disease is as yet unclear.

Source

Neurobiol Aging. 1989 Sep-Oct;10(5):632-3; discussion 648-50.

Journal/Book/Conference Title

Neurobiology of aging

Related Resources

Link to Article in PubMed

PubMed ID

2812241

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