Title
Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients
UMMS Affiliation
Department of Neurology
Publication Date
1987-10-01
Document Type
Article
Subjects
Adult; Blood Platelets; Fatty Acids; Female; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Male; Middle Aged; Multiple Sclerosis
Disciplines
Hematology | Neurology
Abstract
We found a small but statistically significant reduction in the linoleic acid concentration of white blood cells and platelets in MS patients. The percent linoleic acid concentration (mean +/- S.D.) in the white blood cells if 24 MS patients was 8.8 +/- 1.8% as compared with 11.4 +/- 4.9 in 24 age and sex-matched controls (p less than 0.05). Platelet levels were 8.5 +/- 2.4% and 10.6 +/- 3.8% respectively (P less than 0.05). Serum linoleic acid levels were not significantly different in the two groups. The possible role of linoleic acid in the pathogenesis of MS has yet to be defined.
Source
Acta Neurol Scand. 1987 Oct;76(4):241-5.
Journal/Book/Conference Title
Acta neurologica Scandinavica
Related Resources
PubMed ID
3687373
Repository Citation
Fisher M, Johnson MH, Natale AM, Levine PH. (1987). Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients. Neurology Publications and Presentations. Retrieved from https://escholarship.umassmed.edu/neuro_pp/144