Title

Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients

UMMS Affiliation

Department of Neurology

Publication Date

1987-10-01

Document Type

Article

Subjects

Adult; Blood Platelets; Fatty Acids; Female; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Male; Middle Aged; Multiple Sclerosis

Disciplines

Hematology | Neurology

Abstract

We found a small but statistically significant reduction in the linoleic acid concentration of white blood cells and platelets in MS patients. The percent linoleic acid concentration (mean +/- S.D.) in the white blood cells if 24 MS patients was 8.8 +/- 1.8% as compared with 11.4 +/- 4.9 in 24 age and sex-matched controls (p less than 0.05). Platelet levels were 8.5 +/- 2.4% and 10.6 +/- 3.8% respectively (P less than 0.05). Serum linoleic acid levels were not significantly different in the two groups. The possible role of linoleic acid in the pathogenesis of MS has yet to be defined.

Source

Acta Neurol Scand. 1987 Oct;76(4):241-5.

Journal/Book/Conference Title

Acta neurologica Scandinavica

Related Resources

Link to article in PubMed

PubMed ID

3687373

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