Title

Cardiogenic brain embolism and lupus anticoagulant

UMMS Affiliation

Department of Neurology

Publication Date

1989-09-01

Document Type

Article

Subjects

Adult; Blood Coagulation Factors; Brain Ischemia; Echocardiography; Embolism; Heart Diseases; Humans; Intracranial Embolism and Thrombosis; Lupus Coagulation Inhibitor; Male

Disciplines

Cardiology | Medical Immunology | Neurology

Abstract

The lupus anticoagulant, an acquired immunoglobulin associated with an increased tendency for thrombosis, has been linked to the occurrence of cerebral ischemia presumably related to in situ thrombosis. Cardioembolic cerebral ischemic events have rarely been reported. We encountered 2 patients with focal cerebral ischemia, substantial mitral valvular masses, and a circulating lupus anticoagulant. In each, diagnostic evaluation supported a cardioembolic etiology. These findings illustrate the need for evaluating patients with cerebral ischemic events for a cardioembolic source when a circulating lupus anticoagulant is present.

DOI of Published Version

10.1002/ana.410260313

Source

Ann Neurol. 1989 Sep;26(3):390-2. Link to article on publisher's site

Journal/Book/Conference Title

Annals of neurology

Related Resources

Link to article in PubMed

PubMed ID

2508537

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