Death or nonfatal stroke in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction 2.

UMMS Affiliation

Meyers Primary Care Institute; Department of Medicine, Division of Geriatric Medicine; Department of Medicine, Division of Cardiovascular Medicine

Publication Date


Document Type



Age Factors; Aged; Aged, 80 and over; Cerebral Hemorrhage; Female; Hospital Mortality; Humans; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Tissue Plasminogen Activator


Health Services Research | Medicine and Health Sciences


In a retrospective cohort of patients treated in community hospitals, tissue plasminogen activator (t-PA) was associated with decreased odds of in-hospital death or nonfatal stroke. However, the relative benefit was less evident in older patients and women, and some older subgroups did not benefit from treatment.


Am J Cardiol. 2001 Mar 1;87(5):627-30, A9.

Journal/Book/Conference Title

The American journal of cardiology

Related Resources

Link to article in PubMed

PubMed ID