Midlife physical activity preserves lower extremity function in older adults: age gene/environment susceptibility-Reykjavik study
Department of Medicine, Division of Geriatric Medicine; Meyers Primary Care Institute
Aged; Aging; Cognition Disorders; Environmental Exposure; Female; Forecasting; *Genetic Predisposition to Disease; *Geriatric Assessment; Humans; Iceland; Lower Extremity; Male; Morbidity; Motor Activity
Geriatrics | Health Services Research | Primary Care
OBJECTIVES: To examine the long-term association between midlife physical activity (PA) and lower extremity function (LEF) in late life.
DESIGN: Longitudinal study with an average of 25 years of follow-up. SETTING: Community-dwelling old population in Reykjavik, Iceland.
PARTICIPANTS: Four thousand seven hundred fifty-three community-dwelling men and women (mean age 76 +/- 6) in Reykjavik, Iceland.
MEASUREMENTS: On the basis of weekly hours of regular PA reported at the midlife examination, participants were classified as active or inactive. Measures of LEF in late life were gait speed on a 6-m walk, Timed Up and Go (TUG), and knee extension (KE) strength tests. Linear regression analysis was used to examine the association.
RESULTS: Participants who were active in midlife had significantly better LEF (faster gait speed, beta = 0.50, P
CONCLUSION: Regular PA in midlife is associated with better performance of LEF in later life, even after controlling for late-life cognitive function. Geriatrics Society.
DOI of Published Version
J Am Geriatr Soc. 2013 Feb;61(2):237-42. doi: 10.1111/jgs.12077. Link to article on publisher's site
Journal of the American Geriatrics Society
Chang M, Saczynski JS, Snaedal J, Bjornsson S, Einarsson B, Garcia ME, Aspelund T, Siggeirsdottir K, Gudnason V, Launer LJ, Harris TB, Jonsson PV. (2013). Midlife physical activity preserves lower extremity function in older adults: age gene/environment susceptibility-Reykjavik study. Meyers Health Care Institute Publications. https://doi.org/10.1111/jgs.12077. Retrieved from https://escholarship.umassmed.edu/meyers_pp/643