Patient Completion of Laboratory Tests to Monitor Medication Therapy: A Mixed-Methods Study
Meyers Primary Care Institute; Department of Medicine, Division of Geriatric Medicine; Department of Medicine, Division of Preventative and Behavorial Medicine
Medication Therapy Management; Patient Compliance; Diagnostic Tests, Routine
Behavioral Disciplines and Activities | Behavior and Behavior Mechanisms | Community Health and Preventive Medicine | Health Services Research
BACKGROUND: Little is known about the contribution of patient behavior to incomplete laboratory monitoring, and the reasons for patient non-completion of ordered laboratory tests remain unclear.
OBJECTIVE: To describe factors, including patient-reported reasons, associated with non-completion of ordered laboratory tests.
DESIGN: Mixed-Methods study including a quantitative assessment of the frequency of patient completion of ordered monitoring tests combined with qualitative, semi-structured, patient interviews.
PARTICIPANTS: Quantitative assessment included patients 18 years or older from a large multispecialty group practice, who were prescribed a medication requiring monitoring. Qualitative interviews included a subset of show and no-show patients prescribed a cardiovascular, anticonvulsant, or thyroid replacement medication.
MAIN MEASURES: Proportion of recommended monitoring tests for each medication not completed, factors associated with patient non-completion, and patient-reported reasons for non-completion.
KEY RESULTS: Of 27,802 patients who were prescribed one of 34 medications, patient non-completion of ordered tests varied (range: 0-24 %, by drug-test pair). Factors associated with higher odds of test non-completion included: younger patient age (< 40 years vs. >/= 80 years, adjusted odds ratio [AOR] 1.52, 95 % confidence interval [95 % CI] 1.27-1.83); lower medication burden (one medication vs. more than one drug, AOR for non-completion 1.26, 95 % CI 1.15-1.37), and lower visit frequency (0-5 visits/year vs. >/= 19 visits/year, AOR 1.41, 95 % CI 1.25 to 1.59). Drug-test pairs with black box warning status were associated with greater odds of non-completion, compared to drugs without a black box warning or other guideline for testing (AOR 1.91, 95 % CI 1.66-2.19). Qualitative interviews, with 16 no-show and seven show patients, identified forgetting as the main cause of non-completion of ordered tests.
CONCLUSIONS: Patient non-completion contributed to missed opportunities to monitor medications, and was associated with younger patient age, lower medication burden and black box warning status. Interventions to improve laboratory monitoring should target patients as well as physicians.
DOI of Published Version
J Gen Intern Med. 2012 Nov 15. Link to article on publisher's site
Journal of general internal medicine
Fischer SH, Field TS, Gagne SJ, Mazor KM, Preusse P, Reed GW, Peterson DJ, Gurwitz JH, Tjia J. (2012). Patient Completion of Laboratory Tests to Monitor Medication Therapy: A Mixed-Methods Study. Meyers Primary Care Institute Publications. https://doi.org/10.1007/s11606-012-2271-6. Retrieved from https://escholarship.umassmed.edu/meyers_pp/619