Are statins associated with decreased tooth loss in chronic periodontitis

UMMS Affiliation

Meyers Primary Care Institute; Department of Family Medicine and Community Health

Publication Date


Document Type



Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Chronic Disease; Dental Care; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Periodontitis; Smoking; Tooth Loss


Dentistry | Health Services Research | Primary Care


AIM: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis.

MATERIAL AND METHODS: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models.

RESULTS: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use.

CONCLUSIONS: Statin use was not associated with either a decreased or an increased risk of tooth loss.

DOI of Published Version



J Clin Periodontol. 2007 Mar;34(3):214-9. Epub 2007 Jan 25. Link to article on publisher's site

Journal/Book/Conference Title

Journal of clinical periodontology

Related Resources

Link to Article in PubMed

PubMed ID