UMMS Affiliation

Meyers Primary Care Institute

Publication Date


Document Type



Compression Bandages; Postthrombotic Syndrome


Cardiovascular Diseases | Health Services Research | Primary Care


Background. Postthrombotic syndrome (PTS) is a burdensome and costly complication of deep vein thrombosis (DVT). Up to 50% of patients with DVT will develop the disease within two years following the diagnosis of acute DVT. Various risk factors for developing PTS have been identified and different modalities have been used to prevent its development. Compression stockings have been studied for the prevention of PTS in patients diagnosed with proximal DVT.

Methods. MEDLINE and EMBASE databases were searched to identify relevant original articles.

Results. Several trials including two metaanalyses have examined the role of compression stockings for the prevention of PTS. Although most trials showed significant reduction in the development of PTS with the use of compression stockings, limitations in study design prevent the generalizability of the data. Two studies supported an individualized tailored duration especially in patients at low risk for developing the syndrome. A randomized double-blind placebo-controlled trial involving 800 patients is currently ongoing and may confirm the results of older studies.

Conclusions. Clinical trials support the use of compression stockings in patients diagnosed with proximal DVT for the prevention of PTS.

Rights and Permissions

Copyright © 2012 Abir O. Kanaan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI of Published Version



Abir O. Kanaan, Jayne E. Lepage, Shabdis Djazayeri, and Jennifer L. Donovan, “Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature,” Thrombosis, vol. 2012, Article ID 694851, 9 pages, 2012. doi:10.1155/2012/694851. Link to article on publisher's website

Journal/Book/Conference Title


Related Resources

Link to article in PubMed

PubMed ID