Title

An autophagy-independent function for Beclin 1 in cancer

UMMS Affiliation

Department of Molecular, Cell and Cancer Biology; UMass Metabolic Network

Publication Date

1-2-2016

Document Type

Article

Disciplines

Biochemistry | Cancer Biology | Cell Biology | Cellular and Molecular Physiology | Molecular Biology

Abstract

The involvement of Beclin 1 in cancer has been attributed primarily to its role in autophagy initiation. Our recent findings identify a novel, alternative mechanism by which Beclin 1 can impact tumor progression, through the regulation of growth factor receptor signaling.

Keywords

autophagy, beclin 1, cancer, endocytosis, growth factor receptor, signaling

DOI of Published Version

10.1080/23723556.2015.1030539

Source

Mol Cell Oncol. 2016 Jan 2;3(1). pii: e1030539. Epub 2015 Apr 14. Link to article on publisher's site

Journal/Book/Conference Title

Molecular and cellular oncology

Related Resources

Link to Article in PubMed

PubMed ID

26998512

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