Authors
Rando, Oliver J.UMass Chan Affiliations
UMass Metabolic NetworkDepartment of Biochemistry and Molecular Pharmacology
Document Type
Journal ArticlePublication Date
2016-05-02
Metadata
Show full item recordAbstract
The inheritance of information beyond DNA sequence, known as epigenetic inheritance, has been implicated in a multitude of biological processes from control of plant flowering time to cancer in humans. In addition to epigenetic inheritance that occurs in dividing cells of a multicellular organism, it is also increasingly clear that at least some epigenetic information is transmitted via the gametes in a multitude of organisms, including mammals. Here, I review the evidence for epigenetic information carriers in mammalian sperm, and explore the emerging field of intergenerational transfer of environmental information.Source
Cold Spring Harb Perspect Med. 2016 May 2;6(5). pii: a022988. 10.1101/cshperspect.a022988. Link to article on publisher's siteDOI
10.1101/cshperspect.a022988Permanent Link to this Item
http://hdl.handle.net/20.500.14038/36675PubMed ID
26801897Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1101/cshperspect.a022988