UMMS Affiliation

Department of Molecular, Cell and Cancer Biology

Publication Date


Document Type

Letter to the Editor


Cancer Biology | Cell Biology | Cellular and Molecular Physiology | Genetics | Genomics | Hematology | Molecular Biology | Molecular Genetics | Oncology


We have now examined the erythroid phenotype in this zebrafish strain carrying a ZFN genomic knockout of piezo1. Genotyping was performed as previously described. In contrast to the anemic phenotype observed in zebrafish subjected to morpholino knockdown of piezo, the genomic ZFN knockout of piezo1 did not segregate either with anemia in the 3-dpf embryo or with dysmorphic erythrocyte morphology in the adult fish.


PIEZO1, anemia, erythrocyte, morpholino oligomer, zebrafish, zinc-finger nuclease

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Haematologica is an Open Access Publication according to the Budapest Open Access Initiative (per

DOI of Published Version



Haematologica. 2015 Dec;100(12):e483-5. doi: 10.3324/haematol.2015.132449. Epub 2015 Aug 20. Link to article on publisher's site

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Creative Commons License

Creative Commons Attribution 3.0 License
This work is licensed under a Creative Commons Attribution 3.0 License.



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