Luna Lab Publications


Multiple phase equilibria in binary mixtures of phospholipids

UMMS Affiliation

Department of Cell and Developmental Biology



Document Type


Medical Subject Headings

Freeze Fracturing; *Liposomes; Microscopy, Electron; Myristates; Palmitates; *Phosphatidylcholines; *Phosphatidylethanolamines; *Pulmonary Surfactants; Stearates; Thermodynamics


Biochemistry, Biophysics, and Structural Biology | Cell and Developmental Biology


Approximate phse diagrams describing lateral phase separations are given for binary mixtures of dimyristoyl phosphatidylcholine with dipalmitoyl phosphatidylcholine, distearoyl phosphatidycholine, and dipalmitoyl phosphatidylethanolamine. These diagrams are based in part on freeze-fracture electron microscopic data. These phase diagrams represent an improvement over previous studies in that both solid phses (Pbeta' and Lbeta') of the phosphatidylcholines are included. Further consideration is given to the problem of binary mixtures in which there are two Pbeta' phases that do not form a continuous range of solid solutions.


Citation: Biochim Biophys Acta. 1978 Jun 2;509(3):462-73. DOI 10.1016/0005-2736(78)90240-7

At the time of publication, Elizabeth Luna was not yet affiliated with the University of Massachusetts Medical School.

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Link to Article in PubMed

PubMed ID