Title

The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus

UMMS Affiliation

Department of Medicine, Division of Infectious Diseases and Immunology

Publication Date

1996-07-01

Document Type

Article

Disciplines

Immunology and Infectious Disease | Infectious Disease | Virus Diseases

Abstract

To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population.

DOI of Published Version

10.1093/clinids/23.1.189

Source

Davaro RE, Cheeseman SH, Keroack MA, Ellison RT 3rd. The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus. Clin Infect Dis. 1996 Jul;23(1):189-90. doi: 10.1093/clinids/23.1.189. PMID: 8816158. Link to article on publisher's site

Journal/Book/Conference Title

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Related Resources

Link to Article in PubMed

PubMed ID

8816158

Share

COinS