Title

Immunopathogenesis of Dengue hemorrhagic fever

UMMS Affiliation

Center for Infectious Disease and Vaccine Research; Department of Medicine, Division of Infectious Diseases and Immunology

Publication Date

1999-04-25

Document Type

Article

Disciplines

Immunity | Immunology and Infectious Disease | Immunology of Infectious Disease | Infectious Disease | Virology

Abstract

Dengue hemorrhagic fever (DHF) is an acute, potentially life-threatening, capillary leak syndrome caused by the dengue viruses, a group of four antigenically related flaviviruses designated serotypes 1 through 4. First recognized in Southeast Asia in the 1950s, DHF has become a significant public health problem in many countries in tropical and subtropical areas of Asia, the Pacific Rim, and the Americas. In contrast, classical dengue fever, an acute, self-limited febrile illness often called “breakbone fever,” was well recognized before the year 1800. How the same viruses can produce such disparate clinical outcomes has been an area of intense study.

DOI of Published Version

10.1006/viro.1999.9656

Source

Virology. 1999 Apr 25;257(1):1-6. Link to article on publisher's site

Journal/Book/Conference Title

Virology

Related Resources

Link to Article in PubMed

PubMed ID

10208914

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