Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity
Center for Infectious Disease and Vaccine Research; Department of Medicine, Division of Infectious Diseases and Immunology
Immunity | Immunology and Infectious Disease | Immunology of Infectious Disease | Infectious Disease | Medical Immunology | Virology
The goal of this study was to investigate further the role of Th1 cytokines, such as IL-12, and that of counterregulatory Th2 cytokines, such as IL-10, to fur- ther elucidate the possible immunological mechanisms responsible for the development of the plasma leakage seen in dengue hemorrhagic fever.
DOI of Published Version
J Med Virol. 1999 Nov;59(3):329-34. doi:10.1002/(SICI)1096-9071(199911)59:3<329::AID-JMV12>3.0.CO;2-G
Journal of medical virology
Green, Sharone; Vaughn, D. W.; Kalayanarooj, Siripen; Nimmannitya, Suchitra; Suntayakorn, Saroj; Nisalak, Ananda; Rothman, Alan L.; and Ennis, Francis A., "Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity" (1999). Infectious Diseases and Immunology Publications and Presentations. 291.