Title

NIAID workshop on Flavivirus immunity

UMMS Affiliation

Center for Infectious Disease and Vaccine Research; Division of Infectious Diseases and Immunology, Department of Medicine

Publication Date

2010-06-01

Document Type

Article

Disciplines

Immunity | Immunology and Infectious Disease | Immunology of Infectious Disease | Infectious Disease

Abstract

On September 16, 2009, the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National Institutes of Health, convened a workshop to discuss current knowledge of T- and B-cell immune epitopes for members of the Flavivirus genus (family Flaviviridae), and how this information could be used to increase our basic understanding of host-pathogen interactions and/or advance the development of new or improved vaccines and diagnostics for these pathogens. B-cell and T-cell responses to flaviviruses are critical components of protective immunity against these pathogens. However, they have also been linked to disease pathogenesis. A detailed understanding of the biological significance of immune epitope information may provide clues regarding the mechanisms governing the induction of protective versus pathogenic adaptive immune responses.

DOI of Published Version

10.1089/vim.2009.0114

Source

Viral Immunol. 2010 Jun;23(3):235-40. doi: 10.1089/vim.2009.0114. Link to article on publisher's site

Journal/Book/Conference Title

Viral immunology

Related Resources

Link to Article in PubMed

PubMed ID

20565288

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