This collection showcases the journal articles, book chapters, and other publications and presentations written by faculty and researchers of the Department of Medicine's Division of Infectious Diseases and Immunology.
Publications from 2018
New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge, Ana Paula M. M. Almeida, Leopoldo F.M. Machado, Daniel Doro, Frederico C. Nascimento, Leonardo Damasceno, Ricardo T. Gazzinelli, Ana Paula Fernandes, and Caroline Junqueira
Tumor Necrosis Factor-producing T-regulatory Cells Are Associated With Severe Liver Injury in Patients With Acute Hepatitis A, Yoon Seok Choi, Jun R. Huh, and Eui-Cheol Shin
Poorly cytotoxic terminally differentiated CD56(neg)CD16(pos) NK cells accumulate in Kenyan children with Burkitt lymphomas, Catherine Forconi, Cormac P. Cosgrove, Pryia Saikumar-Lakshmi, Christina E. Nixon, Joslyn Foley, John Michael Ong'echa, Juliana A. Otieno, Galit Alter, Christian Munz, and Ann M. Moormann
The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation, Shahrad Hakimian, Yevgeniy Popov, Abbas Rupawala, Karen I. Salomon-Escoto, Steven Hatch, and Randall Pellish
Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission, Thomas Hart, Ngoc Thien Nguyen Thu, Nancy A. Nowak, Fuming Zhang, Robert J. Linhardt, Maria Diuk-Wasser, Sanjay Ram, Peter Kraiczy, and Yi-Pin Lin
Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Tianxiao Huan, Lauren Clancy, Ravi Shah, Emelia J. Benjamin, Daniel Levy, Evelyn A. Kurt-Jones, Kahraman Tanriverdi, and Jane E. Freedman
Splenic Infarction: An Under-recognized Complication of Infectious Mononucleosis?, Yan Li, Ann George, Sami Arnaout, Jennifer P. Wang, and George M. Abraham
Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation, Purvi Mande, Bahar Zirak, Wei-Che Ko, Keyon Taravati, Karen L. Bride, Tia Bumpus Brodeur, April C. Deng, Karen A. Dresser, Zhaozhao Jiang, Rachel Ettinger, Katherine A. Fitzgerald, Michael D. Rosenblum, John E. Harris, and Ann Marshak-Rothstein
The Role of NFκB Factor Relish in Developmentally Programmed Cell Death, Anubhab Nandy
Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women, Kathleen Nudel, Ryan McClure, Matthew Moreau, Emma Briars, A. Jeanine Abrams, Brian Tjaden, Xiao-Hong Su, David Trees, Peter A. Rice, Paola Massari, and Caroline A. Genco
A novel sialylation site on Neisseria gonorrhoeae lipooligosaccharide links heptose II lactose expression with pathogenicity, Sanjay Ram, Sunita Gulati, Lisa A. Lewis, Srinjoy Chakraborti, Bo Zheng, Rosane B. de Oliveira, George W. Reed, Andrew D. Cox, Jianjun Li, Frank St. Michael, Jacek Stupak, Xiao-Hong Su, Sudeshna Saha, Corinna S. Landig, Ajit Varki, and Peter A. Rice
Resistant gonorrhoea: east meets west, Peter A. Rice and Xiao-Hong Su
Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation, Juan Francisco Rodrigues-Alcazar, Marco A. Ataide, Gudrun Engels, Christine Schmitt-Mabmunyo, Natalio Garbi, Wolfgang Kastenmueller, Eicke Latz, and Bernardo S. Franklin
PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy, Verena Rolfes, Christian Idel, Ralph Pries, Kirstin Plotze-Martin, Jens Habermann, Timo Gemoll, Sabine Bohnet, Eicke Latz, Julika Ribbat-Idel, Bernardo S. Franklin, and Barbara Wollenberg
Emergence of the erythroid lineage from multipotent hematopoiesis, Betsabeh K. Tusi, Samuel L. Wolock, Caleb Weinreb, Yung Hwang, Daniel Hidalgo, Rapolas Zilionis, Ari Waisman, Jun R. Huh, Allon M. Klein, and Merav Socolovsky
Increasing Resistance to Azithromycin in Neisseria gonorrhoeae in Eastern Chinese Cities: Resistance Mechanisms and Genetic Diversity among Isolates from Nanjing, Chuan Wan, Yang Li, Wen-Jing Le, Yu-Rong Liu, Sai Li, Bao-Xi Wang, Peter A. Rice, and Xiao-Hong Su
Antiviral Immune Responses to Invertebrate Iridescent Virus 6 in Drosophila, Cara C. West
p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila, Cara C. West and Neal S. Silverman
Publications from 2017
Immunobiology of Long Noncoding RNAs, Maninjay K. Atianand, Daniel R. Caffrey, and Katherine A. Fitzgerald
BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV, Anne K. Barasa, Peng Ye, Meredith Phelps, Ganapathiram T. Arivudainambi, Timelia Tison, and Javier Gordon Ogembo
STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice, Rebecca Baum, Shrutie Sharma, Jason M. Organ, Christopher Jakobs, Veit Hornung, David B. Burr, Ann Marshak-Rothstein, Katherine A. Fitzgerald, and Ellen M. Gravallese
HMGB1, IL-1alpha, IL-33 and S100 proteins: dual-function alarmins, Damien Bertheloot and Eicke Latz
Soluble Uric Acid Activates the NLRP3 Inflammasome, Tarcio Teodoro Braga, Maria Fernanda Forni, Matheus Correa-Costa, Rodrigo Nalio Ramos, Jose Alexandre Barbuto, Paola Branco, Angela Castoldi, Meire Ioshie Hiyane, Mariana Rodrigues Davanso, Eicke Latz, Bernardo S. Franklin, Alicia J. Kowaltowski, and Niels Olsen Saraiva Camara
Therapeutic Antibody Against Neisseria gonorrhoeae Lipooligosaccharide, a Phase-variable Virulence Factor, Srinjoy Chakraborti
Implementing a Fee-for-Service Cervical Cancer Screening and Treatment Program in Cameroon: Challenges and Opportunities, Geneva A. DeGregorio, Simon Manga, Edith Kiyang, Florence Manjuh, Leslie Bradford, Preetam Cholli, Richard Wamai, Rebecca Kemunto Ogembo, Zacharie Sando, Yuxin Liu, Lisa Kennedy Sheldon, Kathleen Nulah, Thomas Welty, Edith Welty, and Javier Gordon Ogembo
A systematic review and meta-analysis on herpes zoster and the risk of cardiac and cerebrovascular events, Nathaniel Erskine, Hoang Tran, Len L. Levin, Christine M. Ulbricht, Joyce D. Fingeroth, Catarina I. Kiefe, Robert J. Goldberg, and Sonal Singh
The Antiviral RNA Interference Response Provides Resistance to Lethal Arbovirus Infection and Vertical Transmission in Caenorhabditis elegans, Don B. Gammon, Takao Ishidate, Lichao Li, Weifeng Gu, Neal S. Silverman, and Craig C. Mello
Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma, Evelyn V. Santos Guerra, Chrono K. Lee, Charles A. Specht, Bhawna Yadav, Haibin Huang, Ali Akalin, Jun R. Huh, Christian Mueller, and Stuart M. Levitz
Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay, Justin Hall, Douglas T. Golenbock, and Eicke Latz
Development of a Reporter System for In Vivo Monitoring of gamma-Secretase Activity in Drosophila, Young Gi Hong, Seyun Roh, Donggi Paik, and Sangyun Jeong
miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN), Parisa Kalantari, Omid F. Harandi, Sarika Agarwal, Florentina Rus, Evelyn A. Kurt-Jones, Katherine A. Fitzgerald, Daniel R. Caffrey, and Douglas T. Golenbock
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring, Sangdoo Kim, Hyunju Kim, Yeong Shin Yim, Soyoung Ha, Koji Atarashi, Tze Guan. Tan, Randy S. Longman, Kenya Honda, Dan R. Littman, Gloria B. Choi, and Jun R. Huh
Association of hospital contact precaution policies with emergency department admission time, Kevin A. Kotkowski, Richard T. Ellison 3rd, Constance Barysauskas, Bruce Barton, Jeroan J. Allison, DeborahAnn Mack, Robert W. Finberg, and Martin A. Reznek
The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis, Kyung J. Kwon-Chung and Stuart M. Levitz
The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis, Kyung J. Kwon-Chung, Stuart M. Levitz, and Arturo Casadevall
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension, Yeong Hann Ling, Shalini M. Krishnan, Christopher T. Chan, Henry Diep, Dorota Ferens, Jaye Chin-Dusting, Barbara K. Kemp-Harper, Chrishan S. Samuel, Timothy D. Hewitson, Eicke Latz, Ashley Mansell, Christopher G. Sobey, and Grant R. Drummond
Investigating the Role of PIR1 and CD200R1 in the Innate Immune Response to Viral Pathogens, Christopher R. MacKay
Screening of TNFalpha, IL-10 and TLR4 single nucleotide polymorphisms in individuals with asymptomatic and chronic cutaneous leishmaniasis in Colombia: a pilot study, Angelica Mera-Ramirez, Andres Castillo, Yenifer Orobio, Maria Adelaida. Gomez, and Carolina Gallego-Marin
Drosophila Model of Leishmania amazonensis Infection, Kendi Okuda and Neal S. Silverman
A Study of Host Factors that Affect Herpes Simplex Virus 1 Pathogenesis: The Role of Cold Sore Susceptibility Gene 1 (CSSG1) in HSV1 Replication, Milan K. Patel
Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent, Sudesh Pawaria, Shrutie Sharma, Rebecca Baum, Kerstin Nundel, Patricia Busto, Ellen M. Gravallese, Katherine A. Fitzgerald, and Ann Marshak-Rothstein
Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice, Elizabeth M. Perez, Joslyn Foley, Timelia Tison, Rute Silva, and Javier Gordon Ogembo
Planning an innovation marathon at an infectious disease conference with results from the International Meeting on Emerging Diseases and Surveillance 2016 Hackathon, John W. Ramatowski, Christopher Xiang Lee, Aikaterini Mantzavino, Joao Ribas, Winter Guerra, Nicholas D. Preston, Eva Schernhammer, Lawrence C. Madoff, and Britta Lassmann
Tuberculosis, human immunodeficiency virus, and the immune reconstitution inflammatory syndrome, Alwyn Rapose and S. Karande
Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2, Jil Sander, Eicke Latz, and Andreas Schlitzer
Microglia in Alzheimer's disease, Heela Sarlus and Michael T. Heneka
Pathways Involved in Recognition and Induction of Trained Innate Immunity by Plasmodium falciparum, Jacob E. Schrum
Reversing behavioural abnormalities in mice exposed to maternal inflammation, Yeong Shin Yim, Sangdoo Kim, Hyunju Kim, Jun R. Huh, and Gloria B. Choi
Interleukin-17: Why the Worms Squirm, Noah J. Silverstein and Jun R. Huh
Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species, Charles A. Specht, Chrono K. Lee, Haibin Huang, Maureen M. Hester, Jianhua Liu, Bridget A. Luckie, Melanie A. Torres Santana, Zeynep Mirza, Payam Khoshkenar, Ambily Abraham, Zu T. Shen, Ali Akalin, Gary R. Ostroff, and Stuart M. Levitz
Drosophilosophical: Re-thinking Adaptive Immunity in the Fly, Cara C. West and Neal S. Silverman
Publications from 2016
Incidence of Dengue Virus Infection in Adults and Children in a Prospective Longitudinal Cohort in the Philippines, Maria Theresa Alera, Anon Srikiatkhachorn, John Mark Velasco, Ilya A. Tac-An, Catherine B. Lago, Hannah Clapham, Stefan Fernandez, Jens W. Levy, Butsaya Thaisomboonsuk, Chonticha Klungthong, Louis R. Macareo, Ananda Nisalak, Laura L. Hermann, Daisy Villa, and In-Kyu Yoon
Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4, Warrison A. Andrade, Sarika Agarwal, Shunyan Mo, Scott A. Shaffer, Joseph P. Dillard, Tobias Schmidt, Veit Hornung, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, and Douglas T. Golenbock
Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production, Warrison A. Andrade, Arnaud Firon, Tobias Schmidt, Veit Hornung, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, Patrick Trieu-Cuot, Douglas T. Golenbock, and Pierre-Alexandre Kaminski
Immunology. An RNA twist to T(H)17 cells, Maninjay K. Atianand and Katherine A. Fitzgerald
A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation, Maninjay K. Atianand, Emiliano P. Ricci, Ankit Bhatta, Stefan A. Schattgen, Jason D. McGowan, Juliana Blin, Joerg E. Braun, Pallavi Gandhi, Melissa J. Moore, Daniel R. Caffrey, and Katherine A. Fitzgerald
An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy, Claudia Bank, Nicholas Renzette, Ping Liu, Sebastian Matuszewski, Hyunjin Shim, Matthieu Foll, Daniel N. Bolon, Konstantin B. Zeldovich, Timothy F. Kowalik, Robert W. Finberg, Jennifer P. Wang, and Jeffrey D. Jensen
Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity, Franck J. Barrat, Keith B. Elkon, and Katherine A. Fitzgerald
Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice, Rebecca Baum, Kerstin Nundel, Sudesh Pawaria, Shrutie Sharma, Patricia Busto, Katherine A. Fitzgerald, Ellen M. Gravallese, and Ann Marshak-Rothstein
A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis, Stephen M. Carpenter, Claudio Nunes-Alves, Matthew G. Booty, Sing Sing Way, and Samuel M. Behar
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons, Elizabeth C. Carroll, Katherine A. Fitzgerald, and Ed C. Lavelle
Phase-Variable Heptose I Glycan Extensions Modulate Efficacy of 2C7 Vaccine Antibody Directed against Neisseria gonorrhoeae Lipooligosaccharide, Srinjoy Chakraborti, Lisa A. Lewis, Andrew D. Cox, Frank St. Michael, Jianjun Li, Peter A. Rice, and Sanjay Ram
Uveitis and Systemic Inflammatory Markers in Convalescent Phase of Ebola Virus Disease, John R. Chancellor, Sriranjani P. Padmanabhan, Thomas C. Greenough, Richard Sacra, Richard T. Ellison III, Lawrence C. Madoff, Rebecca Droms, David Hinkle, George K. Asdourian, Robert W. Finberg, Ute Stroher, Timothy M. Uyeki, and Olga M. Cerón
Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans, Hilary K. Cheesman, Rhonda Feinbaum, Jose Thekkiniath, Robert H. Dowen, Annie L. Conery, and Read Pukkila-Worley
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring, Gloria B. Choi, Yeong S. Yim, Helen Wong, Sangdoo Kim, Hyunju Kim, Sangwon V. Kim, Charles A. Hoeffer, Dan R. Littman, and Jun R. Huh
Long-term activation of the innate immune system in atherosclerosis, Anette Christ, Siroon Bekkering, Eicke Latz, and Niels P. Riksen
Dengue Virus (DENV) Neutralizing Antibody Kinetics in Children After Symptomatic Primary and Postprimary DENV Infection, Hannah Clapham and Sharone Green
Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001, Matthew R. Costa, Justin Pollara, Regina Whitney Edwards, Michael S. Seaman, Miroslaw K. Gorny, David C. Montefiori, Hua-Xin Liao, Guido Ferrari, Shan Lu, and Shixia Wang
Prevalence, Predictors, and Same Day Treatment of Positive VIA Enhanced by Digital Cervicography and Histopathology Results in a Cervical Cancer Prevention Program in Cameroon, Geneva A. DeGregorio, Leslie Bradford, Rebecca Kemunto Ogembo, Yuxin Liu, and Javier Gordon Ogembo
Performance of the G4 Xpert(R) MTB/RIF assay for the detection of Mycobacterium tuberculosis and rifampin resistance: a retrospective case-control study of analytical and clinical samples from high- and low-tuberculosis prevalence settings, Nila J. Dharan, Robert Blakemore, Alexander Sloutsky, Devinder Kaur, Richard C. Alexander, Minoo Ghajar, Kimberlee A. Musser, Vincent E. Escuyer, Marie-Claire Rowlinson, Susanne Crowe, Rafael Laniado-Laborin, Eloise Valli, Pamela Nabeta, Pamela Johnson, and David Alland
Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression, Roland Elling, Jennie Chan, and Katherine A. Fitzgerald
Complete Genome Sequences of Zika Virus Strains Isolated from the Blood of Patients in Thailand in 2014 and the Philippines in 2012, D. W. Ellison and Anon Srikiatkhachorn
The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi, Jonatan Ersching, Jose Ronnie Vasconcelos, Camila P. Ferreira, Braulia C. Caetano, Alexandre Vieira Machado, Oscar Bruna-Romero, Monique A. Baron, Ludmila R.P. Ferreira, Edecio Cunha-Neto, Kenneth L. Rock, Ricardo T. Gazzinelli, and Mauricio Martins Rodrigues
Genomic insights into the Ixodes scapularis tick vector of Lyme disease, Monika Gulia-Nuss,; Daniel R. Caffrey; Neal S. Silverman; Adam R. Wespiser; and Catherine A. Hill
The type three secreted effector SipC regulates the trafficking of PERP during Salmonella infection, Kelly N. Hallstrom and Beth A. McCormick
Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria, Isabella C. Hirako, Marco Antonio Ataide, Lucas Faustino, Patricia A. Assis, Elizabeth W. Sorensen, Hisashi Ueta, Natalia M. Araujo, Gustavo B. Menezes, Andrew D. Luster, and Ricardo T. Gazzinelli
The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury, Bo Hu, Katherine A. Fitzgerald, and Richard A. Flavell
Epstein-Barr Virus Infection of Mammary Epithelial Cells Promotes Malignant Transformation, Hai Hu, Joyce D. Fingeroth, and Gerburg M. Wulf
Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via Stimulator of Interferon Genes., Arvin Iracheta-Vellve, Jan Petrasek, Benedek Gyongyosi, Abhishek Satishchandran, Patrick Lowe, Karen Kodys, Donna Catalano, Charles D. Calenda, Evelyn A. Kurt-Jones, Kate A. Fitzgerald, and Gyongyi Szabo
A Balance between Inhibitor Binding and Substrate Processing Confers Influenza Drug Resistance, Li Jiang, Ping Liu, Claudia Bank, Nicholas Renzette, Kristina L. Prachanronarong, L. Safak Yilmaz, Daniel R. Caffrey, Konstantin B. Zeldovich, Celia A. Schiffer, Timothy F. Kowalik, Jeffrey D. Jensen, Robert W. Finberg, Jennifer P. Wang, and Daniel N. Bolon
Control of the innate immune response by the mevalonate pathway, Zhaozhao Jiang, Celia E. Foster, Annie S. Li, Xiaoman Zhang, Ruth M. Gavin, Sorcha D. Forde, Gail Germain, Susan B. Carpenter, Neal S. Silverman, Ellen M. Gravallese, Katherine A. Fitzgerald, Douglas T. Golenbock, and Donghai Wang
A Model to Explain How the Bacille Calmette Guerin (BCG) Vaccine Drives Interleukin-12 Production in Neonates, Chido Loveness Kathivu and Daniel H. Libraty
Highlights from the 6th International Meeting on Emerging Diseases and Surveillance (IMED 2016) Vienna, Austria from Nov 3 to 7, 2016, Britta Lassmann and Lawrence C. Madoff
Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila, Bo Liu, Yonggang Zheng, Feng Yin, Jianzhong Yu, Neal S. Silverman, and Duojia Pan
DNA immunization as a technology platform for monoclonal antibody induction, Shuying Liu, Shixia Wang, and Shan Lu
ReaDAPting the Role of PGRP-SD in Bacterial Sensing and Immune Activation, Amanda J. Monahan, Anni Kleino, and Neal S. Silverman
Apontic regulates somatic stem cell numbers in Drosophila testes, Amanda J. Monahan and Michelle Starz-Gaiano
Dental Calculus Stimulates Interleukin-1beta Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes, Jorge Luis Montenegro Raudales, Atsutoshi Yoshimura, Ziauddin Sm, Takashi Kaneko, Yukio Ozaki, Takashi Ukai, Toshihiro Miyazaki, Eicke Latz, and Yoshitaka Hara
State-of-the-art monitoring in treatment of dengue shock syndrome: a case series, Steven L. Moulton, Jane Mulligan, Anon Srikiatkhachorn, Siripen Kalanarooj, Greg Z. Grudic, Sharone Green, Robert V. Gibbons, Gary W. Muniz, Carmen Hinojosa-Laborde, Alan L. Rothman, Stephen J. Thomas, and Victor A. Convertino
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling, Clíona Ní Cheallaigh, Jinhee Lee, Kim West, Nuria Martinez, Hardy Kornfeld, Douglas T. Golenbock, and Ed C. Lavelle
Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation, Kendi Okuda, Mei Tong, Brian Dempsey, Kathryn J. Moore, Ricardo T. Gazzinelli, and Neal S. Silverman
How Would Children Register Their Own Births? Insights from a Survey of Students Regarding Birth Registration Knowledge and Policy Suggestions in Kenya, Matthew Pelowski, Richard G. Wamai, Joseph Wangombe, Hellen Nyakundi, Geofrey O. Oduwo, Benjamin K. Ngugi, and Javier Gordon Ogembo
Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI, Susanne Pfeiler, Eicke Latz, and Bernd Engelmann
Surveillance Immunity: An Emerging Paradigm of Innate Defense Activation in Caenorhabditis elegans, Read Pukkila-Worley
CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice, Alejandor Ramirez, Mary Dawn T. Co, and Anuja Mathew
Inflammasome Complexes: Emerging Mechanisms and Effector Functions, Vijay A.K. Rathinam and Katherine A. Fitzgerald
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation, Dmitry Ratner, M. Pontus A. Orning, Megan K. Proulx, Donghai Wang, Mikhail A. Gavrilin, Mark D. Wewers, Emad S. Alnemri, Peter F. Johnson, Bettina Lee, Joan Mecsas, Nobuhiko Kayagaki, Jon D. Goguen, and Egil Lien
Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS, Line S. Reinert, Katarina Lopusna, Henriette Winther, Chenglong Sun, Martin K. Thomsen, Ramya Nandakumar, Trine H. Mogensen, Morten Meyer, Christian Vaegter, Jens R. Nyengaard, Katherine A. Fitzgerald, and Soren R. Paludan
Reconstruction of 60 Years of Chikungunya Epidemiology in the Philippines Demonstrates Episodic and Focal Transmission, Henrik Salje and Anon Srikiatkhachorn