This collection showcases the journal articles, book chapters, and other publications and presentations written by faculty and researchers of the Department of Medicine's Division of Infectious Diseases and Immunology.

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Publications from 2020

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Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Listeria monocytogenes Infection, Federica Agliano, Katherine A. Fitzgerald, Anthony T. Vella, Vijay A. Rathinam, and Andrei E. Medvedev

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Remdesivir for the Treatment of Covid-19 - Preliminary Report, John H. Beigel, Robert W. Finberg, and ACTT-1 Study Group Members

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Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19, Charles Calisher, Dennis Carroll, Rita Colwell, Ronald B. Corley, Peter Daszak, Christian Drosten, Luis Enjuanes, Jeremy Farrar, Hume Field, Josie Golding, Alexander Gorbalenya, Bart Haagmans, James M. Hughes, William B. Karesh, Gerald T. Keusch, Sai Kit Lam, Juan Lubroth, John S. Mackenzie, Lawrence C. Madoff, Jonna Mazet, Peter Palese, Stanley Perlman, Leo Poon, Bernard Roizman, Linda Saif, Kanta Subbarao, and Mike Turner

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Single-cell analysis of upper airway cells reveals host-viral dynamics in influenza infected adults, Yuming Cao, Zhiru Guo, Pranitha Vangala, Elisa Donnard, Ping Liu, Patrick McDonel, Jose Ordovas Montanes, Alex K. Shalek, Robert W. Finberg, Jennifer P. Wang, and Manuel Garber

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Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors, Paul Dembny, Douglas T. Golenbock, and Seija Lehnardt

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Infectious disease outbreaks among forcibly displaced persons: an analysis of ProMED reports 1996-2016, Angel N. Desai, John W. Ramatowski, Nina Marano, Lawrence C. Madoff, and Britta Lassmann

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Innate Immunity in the C. elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development, Kyle J. Foster, Hilary K. Cheesman, Pengpeng Liu, Nicholas D. Peterson, Sarah M. Anderson, and Read Pukkila-Worley

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beta-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia, Lea L. Friker, Hannah Scheiblich, Inga V. Hochheiser, Rebecca Brinkschulte, Dietmar Riedel, Eicke Latz, Matthias Geyer, and Michael T. Heneka

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Acute Pneumonia, Steven C. Hatch

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CNS Infections, Part 1 and Part 2, Steven C. Hatch

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COVID-19 and Severe Acute Respiratory Infection, Steven C. Hatch

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COVID-19, Ebola, Spacesuits, and Infection Control: What PPE Does for HCWs, Steven C. Hatch

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Gram Negative Bacteria in Clinical Medicine, Steven C. Hatch

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Gram Positive Bacteria in Clinical Medicine, Steven C. Hatch

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Molecular Diagnostics, Steven C. Hatch

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Skin and Soft-Tissue Infections, Steven C. Hatch

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Immediate and long-term consequences of COVID-19 infections for the development of neurological disease, Michael T. Heneka, Douglas T. Golenbock, Eicke Latz, Dave Morgan, and Robert H. Brown Jr.

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A genome-wide screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation, Michael C. Kiritsy, Michigan State University, Michigan State University, Michigan State University, Audrey E. Lord, M. Pontus A. Orning, Roland Elling, Katherine A. Fitzgerald, and Michigan State University

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PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment, Luca Kleineidam, Michael T. Heneka, and Alfredo Ramirez

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Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events, Jacob Lemieux, Katherine J. Siddle, Jeremy Luban, Glen R. Gallagher, Lawrence C. Madoff, Sandra Smole, Virginia M. Pierce, Eric Rosenberg, Pardis C. Sabeti, Daniel J. Park, and Bronwyn L. MacInnis

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Epidemic to Endemic or Pandemic Infectious Diseases: Commonalities and Distinctions between Malaria, Ebola and COVID19, Ann M. Moormann

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Cytosolic DNA sensing in autoimmune and autoinflammatory diseases, Mona Motwani

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Defining trained immunity and its role in health and disease, Mihai G. Netea and Eicke Latz

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Addressing decontaminated respirators: Some methods appear to damage mask integrity and protective function, Richard E. Peltier, Jiayuan Wang, Brian L. Hollenbeck, Jennifer Lanza, Ryan M. Furtado, Jay Cyr, Richard T. Ellison III, and Kimiyoshi J. Kobayashi

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The impact of changes in Clinical Microbiology Laboratory location and ownership on the practice of Infectious Diseases, Michael Pentella, Melvin P. Weinstein, Susan E. Beekmann, Philip M. Polgreen, and Richard T. Ellison III

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Li Wenliang, a face to the frontline healthcare worker. The first doctor to notify the emergence of the SARS-CoV-2, (COVID-19), outbreak, Eskild Petersen, David Hui, Davidson H. Hamer, Lucille Blumberg, Lawrence C. Madoff, Marjorie Pollack, Shui Shan Lee, Susan McLellan, Ziad Memish, Ira Praharaj, Sean Wasserman, Francine Ntoumi, Esam Ibraheem Azhar, Timothy D. Mchugh, Richard Kock, Guiseppe Ippolito, Ali Zumla, and Marion Koopmans

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COVID-19 Travel Restrictions and the International Health Regulations - Call for an Open Debate on Easing of Travel Restrictions, Eskild Petersen, Brian McCloskey, David S. Hui, Richard Kock, Francine Ntoumi, Ziad A. Memish, Nathan Kapata, Esam I. Azhar, Marjorie Pollack, Lawrence C. Madoff, Davidson H. Hamer, Jean B. Nachega, N. Pshenichnaya, and Alimuddin Zumla

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Periodic Parasites and Daily Host Rhythms, Kimberley F. Prior, Filipa Rijo-Ferreira, Patricia A. Assis, Isabella C. Hirako, David R. Weaver, Ricardo T. Gazzinelli, and Sarah E. Reece

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Journal Club discussion of "Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study", Sanjay Ram and Stuart M. Levitz

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Platelets Fuel the Inflammasome Activation of Innate Immune Cells, Verena Rolfes, Lucas Secchim Ribeiro, Eicke Latz, Moshe Arditi, and Bernardo Simoes Franklin

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Evaluation of pre-processing on the meta-analysis of DNA methylation data from the Illumina HumanMethylation450 BeadChip platform, Claudia Sala, Pietro Di Lena, Danielle Fernandes Durso, Andrea Prodi, Gastone Castellani, and Christine Nardini

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PFRED: A computational platform for siRNA and antisense oligonucleotides design, Simone Sciabola, Hualin Xi, Dario Cruz, Qing Cao, Christine Lawrence, Tianhong Zhang, Sergio Rotstein, Jason D. Hughes, Daniel R. Caffrey, and Robert Stanton

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SARS-Coronavirus-2 nucleocapsid protein measured in blood using a Simoa ultra-sensitive immunoassay differentiates COVID-19 infection with high clinical sensitivity., Dandan Shan, Eicke Latz, and Andrew J. Ball

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Maternal Anti-Dengue IgG Fucosylation Predicts Susceptibility to Dengue Disease in Infants, Natalie K. Thulin, R. Camille Brewer, Robert Sherwood, Stylianos Bournazos, Karlie G. Edwards, Nitya S. Ramadoss, Jeffery K. Taubenberger, Matthew Memoli, Andrew J. Gentles, Prasanna Jagannathan, Sheng Zhang, Daniel H. Libraty, and Taia T. Wang

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Combining genomics and epidemiology to track mumps virus transmission in the United States, Shirlee Wohl, Lawrence C. Madoff, and Bronwyn L. MacInnis

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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues, Carly G. K. Ziegler, Yuming Cao, Zhiru Guo, Jennifer P. Wang, Robert W. Finberg, Manuel Garber, Alex K. Shalek, Jose Ordovas-Montanes, and HCA Lung Biological Network

Publications from 2019

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A novel vaccine platform using glucan particles for induction of protective responses against Francisella tularensis and other pathogens, Ambily Abraham, Gary R. Ostroff, Stuart M. Levitz, and P. C. F. Oyston

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Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis, Camila Alvarez-Silva, Robert Schierwagen, Alessandra Pohlmann, Fernando Magdaleno, Frank E. Uschner, Patrick Ryan, Maria J.G.T. Vehreschild, Joan Claria, Eicke Latz, Benjamin Lelouvier, Manimozhiyan Arumugam, and Jonel Trebicka

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The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans, Sarah M. Anderson, Hilary K. Cheesman, Nicholas D. Peterson, Elisabeth B. Salisbury, Alexander A. Soukas, and Read Pukkila-Worley

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A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection, Lindsey E. Bazzone, Michael King, Christopher R. MacKay, Pyae Phyo Kyawe, Paul Meraner, Daniel Lindstrom, Joselyn Rojas-Quintero, Caroline A. Owen, Jennifer P. Wang, Abraham L. Brass, Evelyn A. Kurt-Jones, and Robert W. Finberg

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A Meningococcal Native Outer Membrane Vesicle Vaccine With Attenuated Endotoxin and Overexpressed Factor H Binding Protein Elicits Gonococcal Bactericidal Antibodies, Peter T. Beernink, Emma Ispasanie, Lisa A. Lewis, Sanjay Ram, Gregory R. Moe, and Dan M. Granoff

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C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections, Serena Bettoni, Jutamas Shaughnessy, Karolina Maziarz, David Ermert, Sunita Gulati, Bo Zheng, Matthias Morgelin, Susanne Jacobsson, Kristian Riesbeck, Magnus Unemo, Sanjay Ram, and Anna M. Blom

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Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis, Korbinian Bosl and Richard K. Kandasamy

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RE: Preventability of hospital onset bacterermia and fungemia: A pilot study of potential healthcare-associated infection outcome measure, by Dantes et al (2019), Anna M. Civitarese, Eric Ruggieri, Debbie Mack, Stephen O. Heard, Michael Mitchell, Craig M. Lilly, Karen E. Landry, Richard T. Ellison III, and J Matthias Walz

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Presentation and Treatment Outcomes of Liberian Children Age 5 Years and Under Diagnosed With Severe Malaria, Benetta Collins-Andrews, Patricia A. McQuilkin, Kanagasabai Udhayashankar, Eric Adu, and Ann M. Moormann

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Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting, Anthony D. Cristillo and Peter A. Rice

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Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3, Pan Deng, Nandhitha Uma Naresh, Yunguang Du, Lilian T. Lamech, Jun Yu, Lihua Julie Zhu, Read Pukkila-Worley, and Cole M. Haynes

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The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH), Hannah K. Drescher, Ralf Weiskirchen, Annabelle Fulop, Carsten Hopf, Estibaliz Gonzalez de San Roman, Pitter F. Huesgen, Alain de Bruin, Laura Bongiovanni, Anette Christ, Rene Tolba, Christian Trautwein, and Daniela C. Kroy

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A cross-sectional analysis of factors associated with detection of oncogenic human papillomavirus in human immunodeficiency virus-infected and uninfected Kenyan women, A. Ermel, P. Tonui, M. Titus, Y. Tong, N. Wong, J. Ong'echa, K. Muthoka, S. Kiptoo, Ann M. Moormann, J. Hogan, A. Mwangi, S. Cu-Uvin, P. J. Loehrer, O. Orang'o, and D. Brown

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The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus, David Ermert, Maisem Laabei, Antonin Weckel, Matthias Morgelin, Martin Lundqvist, Lars Bjorck, Sanjay Ram, Sara Linse, and Anna M. Blom

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The emergence of pathogenic TNF/iNOS producing dendritic cells (Tip-DCs) in a malaria model of acute respiratory distress syndrome (ARDS) is dependent on CCR4, Bruno Galvao-Filho, Julia Teixeira de Castro, Maria Marta Figueiredo, Claudio Goncalves Rosmaninho, Lis Ribeiro do Valle Antonelli, and Ricardo T. Gazzinelli

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Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody, Sunita Gulati, Frank J. Beurskens, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Nancy Nowak, Peter A. Rice, and Sanjay Ram

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Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine, Sunita Gulati, Michael W. Pennington, Andrzej Czerwinski, Darrick Carter, Bo Zheng, Nancy Nowak, Rosane B. DeOliveira, Jutamas Shaughnessy, George W. Reed, Sanjay Ram, and Peter A. Rice

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Targeting Lipooligosaccharide (LOS) for a Gonococcal Vaccine, Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram, and Peter A. Rice

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Streptolysin O Induces the Ubiquitination and Degradation of Pro-IL-1beta, Dora Hancz, Elsa Westerlund, Christine Valfridsson, Getachew Melkamu Aemero, Benedicte Bastiat-Sempe, M. Pontus A. Orning, Egil Lien, Michael R. Wessels, and Jenny J. Persson

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Lab Values in Research: an Introduction, Steven C. Hatch

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Scientific Posters, Steven C. Hatch

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Using Powerpoint in Medical Presentations: A User’s Guide, Steven C. Hatch

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Using PowerPoint in presentations: a guide, Steven C. Hatch

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Alternative splicing regulates stochastic NLRP3 activity, Florian Hoss, James L. Mueller, Francisca Rojas Ringeling, Juan F. Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D. Putnam, Richard D. Kolodner, Stefan Canzar, Matthias Geyer, Hal M. Hoffman, and Eicke Latz

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Epstein Barr virus genomes reveal population structure and type 1 association with endemic Burkitt lymphoma, Yasin Kaymaz, Cliff Oduor, Ozkan Aydemir, Micah Luftig, Juliana Otieno, John Michael Ong'echa, Jeffrey A. Bailey, and Ann M. Moormann

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Candida albicans Factor H Binding Molecule Hgt1p - A Low Glucose-Induced Transmembrane Protein Is Trafficked to the Cell Wall and Impairs Phagocytosis and Killing by Human Neutrophils, Samyr Kenno, Cornelia Speth, Gunter Rambach, Ulrike Binder, Sneha Chatterjee, Rita Caramalho, Hubertus Haas, Cornelia Lass-Florl, Jutamas Shaughnessy, Sanjay Ram, Neil A.R. Gow, Dorothea Orth-Holler, and Reinhard Wurzner

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Regulation of the Drosophila Imd pathway by signaling amyloids, Anni Kleino and Neal S. Silverman

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Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension, Shalini M. Krishnan, Eicke Latz, and Grant R. Drummond

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Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii, Woei C. Lam, Rajendra Upadhya, Charles A. Specht, Abigail E. Ragsdale, Camaron R. Hole, Stuart M. Levitz, and Jennifer K. Lodge

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Chitosan biosynthesis and virulence in the human fungal pathogen Cryptococcus gattii, Woei C. Lam, Rajendra Upadhya, Charles A. Specht, Abigail E. Ragsdale, Camaron R. Hole, Stuart M. Levitz, and Jennifer K. Lodge

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Evolution of the exclusively human pathogen Neisseria gonorrhoeae: Human-specific engagement of immunoregulatory Siglecs, Corinna S. Landig, Ashley Hazel, Benjamin P. Kellman, Jerry J. Fong, Flavio Schwarz, Sarika Agarwal, Nissi Varki, Paola Massari, Nathan E. Lewis, Sanjay Ram, and Ajit Varki

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Role of Gonococcal Neisserial Surface Protein A (NspA) in Serum Resistance and Comparison of Its Factor H Binding Properties with Those of Its Meningococcal Counterpart, Lisa A. Lewis, Peter A. Rice, and Sanjay Ram

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A framework for assessing the lifetime economic burden of congenital cytomegalovirus in the United States, Aaron Lucas, Anushua Sinha, Karen B. Fowler, Deirdre Mladsi, Christine Barnett, Salome Samant, and Laura L. Gibson

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Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts, Ashley L. Marcinkiewicz, Alan P. Dupuis 2nd, Maxime Zamba-Campero, Nancy Nowak, Peter Kraiczy, Sanjay Ram, Laura D. Kramer, and Yi-Pin Lin

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The aminoalkylindole, BML-190, negatively regulates chitosan synthesis via the cAMP/PKA1 pathway in Cryptococcus neoformans, Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Ma Xenia G. Ilagan, Maureen J. Donlin, and Jennifer K. Lodge

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The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans, Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Xenia G. Ilagan, Maureen J. Donlin, and Jennifer K. Lodge

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Planning and Conducting a Research Survey, Ann M. Moormann

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Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models, Mona Motwani, Sudesh Pawaria, Jennifer Bernier, Stephanie Moses, Kate Henry, Terry Fang, Linda Burkly, Ann Marshak-Rothstein, and Katherine A. Fitzgerald

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Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia, Mercedeh J. Movassagh, Cliff Oduor, Catherine Forconi, Ann M. Moormann, and Jeffrey A. Bailey

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Redirection of SKN-1 abates the negative metabolic outcomes of a perceived pathogen infection, James D. Nhan, Christian D. Turner, Sarah M. Anderson, Chia-An Yen, Hans M. Dalton, Hilary K. Cheesman, Dana L. Ruter, Nandhitha Uma Naresh, Cole M. Haynes, Alexander A. Soukas, Read Pukkila-Worley, and Sean P. Curran

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The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans, Nicholas D. Peterson, Hilary K. Cheesman, Pengpeng Liu, Sarah M. Anderson, Kyle J. Foster, Richa Chhaya, Paola N. Perrat, Jose Thekkiniath, Qiyuan Yang, Cole M. Haynes, and Read Pukkila-Worley

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CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge, Camila Pontes Ferreira, Leonardo Moro Cariste, Barbara Ferri Moraschi, Bianca Ferrarini Zanetti, Sang Won Han, Daniel Araki Ribeiro, Alexandre Vieira Machado, Joseli Lannes-Vieira, Ricardo T. Gazzinelli, and Jose Ronnie Vasconcelos Carvalho

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Searching Using Google Scholar and PubMed, Sanjay Ram

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Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1beta Inflammation in Human Macrophages, Juan Francisco Rodriguez-Alcazar, Marco Antonio Ataide, Gudrun Engels, Christine Schmitt-Mabmunyo, Natalio Garbi, Wolfgang Kastenmuller, Eicke Latz, and Bernardo S. Franklin

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Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis, Joseph Sarhan, Beiyun C. Liu, Hayley I. Muendlein, Chi G. Weindel, Irina Smirnova, Amy Y. Tang, Vladimir Ilyukha, Maxim Sorokin, Anton Buzdin, Katherine A. Fitzgerald, and Alexander Poltorak

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Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment, Kelly L. Singel, Sanjay Ram, and Brahm H. Segal

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The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2, Astrid Skjesol, Douglas T. Golenbock, and Harald Husebye

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NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity, Marina Sokolova, Egil Lien, Ivar Sjaastad, Mieke C. Louwe, Katrine Alfsnes, Jan Magnus Aronsen, Lili Zhang, Solveig B. Haugstad, Bard Andre Bendiksen, Jonas Ogaard, Marte Bliksoen, Rolf K. Berge, Pal Aukrust, Trine Ranheim, and Arne Yndestad

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Online Sharing of Documents: the Mobile Office, Rebecca Sulyma, Sanjay Ram, and Steven C. Hatch

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Systemic inflammation impairs microglial Abeta clearance through NLRP3 inflammasome, Dario Tejera, Dilek Mercan, Juan M. Sanchez-Caro, Mor Hanan, David Greenberg, Hermona Soreq, Eicke Latz, Douglas T. Golenbock, and Michael T. Heneka

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IIV-6 Inhibits NF-kappaB Responses in Drosophila, Cara C. West, Florentina Rus, Ying Chen, Anni Kleino, Monique Gangloff, Don B. Gammon, and Neal S. Silverman

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Control of antiviral innate immune response by protein geranylgeranylation, Shigao Yang, Zhaozhao Jiang, Katherine A. Fitzgerald, and Donghai Wang

Publications from 2018

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New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge, Ana Paula M. M. Almeida, Leopoldo F.M. Machado, Daniel Doro, Frederico C. Nascimento, Leonardo Damasceno, Ricardo T. Gazzinelli, Ana Paula Fernandes, and Caroline Junqueira

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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis, Ishita Banerjee, Bharat Behl, Morena Mendonca, Gaurav Shrivastava, Ashley J. Russo, Antoine Menoret, Arundhati Ghosh, Anthony T. Vella, Sivapriya Kailasan. Vanaja, Saumendra N. Sarkar, Katherine A. Fitzgerald, and Vijay A. Rathinam K

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Tumor Necrosis Factor-producing T-regulatory Cells Are Associated With Severe Liver Injury in Patients With Acute Hepatitis A, Yoon Seok Choi, Jun R. Huh, and Eui-Cheol Shin

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Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2, Alexiane Decout, Devinder Kaur, and Jerome Nigou

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Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling, Dominic De Nardo, Katherine R. Balka, Yamel Cardona Gloria, Vikram R. Rao, Eicke Latz, and Seth L. Masters

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Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine, Wei Ding, Daniel P. Higgins, Dilip K. Yadav, Adwait A. Godbole, Read Pukkila-Worley, and Amy K. Walker

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Upregulation of HLA-E by dengue and not Zika viruses, Elena Drews, Awadalkareem Adam, Phone Htoo, Elizabeth Townsley, and Anuja Mathew

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Complete and Durable Responses in Primary Central Nervous System Posttransplant Lymphoproliferative Disorder with Zidovudine, Ganciclovir, Rituximab, and Dexamethasone, James P. Dugan, Joyce D. Fingeroth, and Robert A. Baiocchi

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Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2, Roland Elling, Zhaozhao Jiang, Shiuli Agarwal, Mona Motwani, Jennie Chan, Shrutie Sharma, Katherine A. Fitzgerald, and Susan Carpenter

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Poorly cytotoxic terminally differentiated CD56(neg)CD16(pos) NK cells accumulate in Kenyan children with Burkitt lymphomas, Catherine Forconi, Cormac P. Cosgrove, Pryia Saikumar-Lakshmi, Christina E. Nixon, Joslyn Foley, John Michael Ong'echa, Juliana A. Otieno, Galit Alter, Christian Munz, and Ann M. Moormann

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Protective versus pathologic pre-exposure cytokine profiles in dengue virus infection, Heather Friberg, Coreen M. Beaumier, Sangshin Park, Pamela P. Pazoles, Timothy P. Endy, Anuja Mathew, Jeffrey R. Currier, Richard G. Jarman, Kathryn B. Anderson, Steven Hatch, Stephen J. Thomas, and Alan L. Rothman

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Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria, Carolina Gallego-Marin, Jacob E. Schrum, Warrison A. Andrade, Scott A. Shaffer, Lina F. Giraldo, Alvaro M. Lasso, Evelyn A. Kurt-Jones, Katherine A. Fitzgerald, and Douglas T. Golenbock