Since the school's inception in 1979, students in the Morningside Graduate School of Biomedical Sciences at UMass Chan Medical School have contributed thousands of research publications to the field of biomedical sciences. This collection makes this body of work accessible to our students, faculty, potential recruits, the citizens of Massachusetts, and the world.

Attention students: Click on Submit Research in the left sidebar to submit your journal articles, posters, and presentations, after reviewing the Submission Guidelines. (Theses and dissertations should be submitted to Dissertations and Theses). You’ll need to log in or create a free account. If your publication appears in PubMed, you can enter the PubMed ID and information from PubMed will be used to populate the submission form. Questions? Contact escholarship@umassmed.edu.

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Publications from 2018

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Higher-Order Organization Principles of Pre-translational mRNPs, Mihir Metkar, Hakan Ozadam, Bryan R. Lajoie, Maxim Imakaev, Leonid A. Mirny, Job Dekker, and Melissa J. Moore (Molecular cell, 2018-11-15)

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JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory, Caroline Morel, Tessi Sherrin, Norman J. Kennedy, Kelly H. Forest, Seda Barutcu, Michael Robles, Ezekiel Carpenter-Hyland, Naghum Alfulaij, Claire L. Standen, Robert A. Nichols, Morris Benveniste, Roger J. Davis, and Cedomir Todorovic

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ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes, Kenan C. Murphy, Samantha J. Nelson, Subhalaxmi Nambi, Kadamba Papavinasasundaram, Christina E. Baer, and Christopher M. Sassetti

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HLA-DO modulates the diversity of the MHC-II self-peptidome, Padma P. Nanaware, Mollie M. Jurewicz, John D. Leszyk, Scott A. Shaffer, and Lawrence J. Stern

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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release, Maria P. Negroni and Lawrence J. Stern

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Red wine and green tea flavonoids are cis-allosteric activators and competitive inhibitors of GLUT1-mediated sugar uptake, Ogooluwa A. Ojelabi, Kenneth P. Lloyd, Julie K. De Zutter, and Anthony Carruthers

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Molecular Mechanisms Directing Spine Outgrowth and Synaptic Partner Selection in Caenorhabditis elegans, Devyn Oliver, Kellianne Alexander, and Michael M. Francis

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Numerous recursive sites contribute to accuracy of splicing in long introns in flies, Athma A. Pai, Joseph M. Paggi, Paul Yan, Karen Adelman, and Christopher B. Burge

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Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress, Min Peng, Ke Cong, Nicholas J. Panzarino, Sumeet Nayak, Jennifer Calvo, Bin Deng, Lihua Julie Zhu, Monika Morocz, Lili Hegedus, Lajos Haracska, and Sharon B. Cantor

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Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis, Owen M. Peters, Elizabeth A. Lewis, Jeannette M. Osterloh, Alexandra Weiss, Johnny Salameh, Jake P. Metterville, Robert H. Brown Jr., and Marc R. Freeman

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Neurexin directs partner-specific synaptic connectivity in C. elegans, Alison Philbrook, Shankar Ramachandran, Christopher M. Lambert, Devyn Oliver, Jeremy Florman, Mark J. Alkema, Michele Lemons, and Michael M. Francis

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Mutations in influenza A virus neuraminidase and hemagglutinin confer resistance against a broadly neutralizing hemagglutinin stem antibody, Kristina L. Prachanronarong, Aneth S. Canale, Ping Liu, Mohan Somasundaran, Shurong Hou, Yu-Ping Poh, Thomas Han, Quan Zhu, Nicholas Renzette, Konstantin B. Zeldovich, Timothy F. Kowalik, Nese Kurt Yilmaz, Jeffrey D. Jensen, Daniel N. Bolon, Wayne A. Marasco, Robert W. Finberg, Celia A. Schiffer, and Jennifer P. Wang

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Varicosities affecting the lower limb veins consequent to a unique variant drainage pattern of the small saphenous vein, Shauna Mary Rice, Elke Sarah Schipani, Ana Maleesa Rae Santos, Katherine Anais Sadaniantz, Prithwijit Roychowdhury, Eustathia Lela Giannaris, and Manas Das

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Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo, Jillian M. Richmond, James P. Strassner, Lucio Zapata Jr., Madhuri Garg, Rebecca L. Riding, Maggi A. Refat, Xueli Fan, Vincent Azzolino, Andrea Tovar-Garza, Naoya Tsurushita, Amit G. Pandya, J Yun Tso, and John E. Harris

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Correlates of specialty substance use treatment among adults with opioid use disorders, Eric Romo, Christine M. Ulbricht, Robin E. Clark, and Kate L. Lapane

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Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants, Linah Rusere, Ashley N. Matthew, Gordon J. Lockbaum, Muhammad Jahangir, Alicia Newton, Christos J. Petropoulos, Wei Huang, Nese Kurt Yilmaz, Celia A. Schiffer, and Akbar Ali

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IMP3 Stabilization of WNT5B mRNA Facilitates TAZ Activation in Breast Cancer, Sanjoy Samanta, Santosh Guru, Ameer L. Elaimy, John J. Amante, Jianhong Ou, Jun Yu, Lihua Julie Zhu, and Arthur M. Mercurio

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MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease, Abhishek Satishchandran, Aditya Ambade, Sitara Rao, Ying-Chao Hsueh, Arvin Iracheta-Vellve, David Tornai, Patrick Lowe, Benedek Gyongyosi, Jia Li, Donna Catalano, Li Zhong, Karen Kodys, Jun Xie, Shashi Bala, Guangping Gao, and Gyongyi Szabo

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CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure, Yuefei Shen, Jessica L. Cohen, Sarah M. Nicoloro, Mark Kelly, Batuhan Yenilmez, Felipe Henriques, Emmanouela Tsagkaraki, Yvonne J. K. Edwards, Xiaodi Hu, Randall H. Friedline, Jason K. Kim, and Michael P. Czech

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Recruiting low-income postpartum women into two weight loss interventions: in-person versus Facebook delivery, Valerie J. Silfee, Andrea Lopez-Cepero, Stephenie C. Lemon, Barbara Estabrook, Oanh Nguyen, and Milagros C. Rosal

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Adapting a Behavioral Weight Loss Intervention for Delivery via Facebook: A Pilot Series Among Low-Income Postpartum Women, Valerie J. Silfee, Andrea Lopez-Cepero, Stephenie C. Lemon, Barbara Estabrook, Oanh Nguyen, Monica L. Wang, and Milagros C. Rosal

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Membrane protein nanoparticles: the shape of things to come, Kailene S. Simon, Naomi L. Pollock, and Sarah C. Lee

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Understanding and repurposing CRISPR-mediated alternative splicing, Jordan L. Smith, Haiwei Mou, and Wen Xue

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Systematic pan-cancer analysis of somatic allele frequency, Liam Spurr, Muzi Li, Nawaf Alomran, Qianqian Zhang, Paula Restrepo, Mercedeh Movassagh, Chris Trenkov, Nerissa Tunnessen, Tatiyana Apanasovich, Keith A. Crandall, Nathan Edwards, and Anelia Horvath

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Does provider advice to increase physical activity differ by activity level among US adults with cardiovascular disease risk factors?, Meera Sreedhara, Valerie J. Silfee, Milagros C. Rosal, Molly E. Waring, and Stephenie C. Lemon

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A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein, Nicholas P. Stone, Brendan J. Hilbert, Daniel Hidalgo, Kevin T. Halloran, Jooyoung Lee, Erik J. Sontheimer, and Brian A. Kelch

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Targeted Delivery of Bioactive Molecules for Vascular Intervention and Tissue Engineering, Hannah A. Strobel, Elisabet I. Qendro, Eben Alsberg, and Marsha W. Rolle

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Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis, Rose L. Szabady, Christopher Louissaint, Anneke Lubben, Bailu Xie, Shaun Reeksting, Christine Tuohy, Zachary Demma, Sage Foley, Christina S. Faherty, Alejandro Llanos-Chea, Andrew J. Olive, Randall J. Mrsny, and Beth A. McCormick

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Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice, TeChen Tzeng, Yuto Hasegawa, Risa Iguchi, Amy Cheung, Daniel R. Caffrey, Elizabeth Jeanne Thatcher, Wenjie Mao, Gail Germain, Nelsy DePaula Tamburro, Shigeo Okabe, Michael T. Heneka, Eicke Latz, Kensuke Futai, and Douglas T. Golenbock

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Functionally Complete Excision of Conditional Alleles in the Mouse Suprachiasmatic Nucleus by Vgat-ires-Cre, David R. Weaver, Vincent van der Vinne, Eustathia Lela Giannaris, Thomas J. Vajtay, Kristopher L. Holloway, and Christelle Anaclet

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p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila, Cara C. West and Neal S. Silverman

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Microtubule Acetylation Is Required for Mechanosensation in Drosophila, Connie Yan, Fei Wang, Yang Xiang, Stephen L. Rogers, and Jay Z. Parrish

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A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals [preprint], Phillip D. Zamore, Ildar Gainetdinov, Cansu Colpan, and Katharine Cecchini

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Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin, Gen Zhang, Shikui Tu, Tianxiong Yu, Xiao-Ou Zhang, Swapnil S. Parhad, Zhiping Weng, and William E. Theurkauf

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Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection, Andrew Zukauskas, Randall J. Mrsny, Paula Cortes Barrantes, Jerrold R. Turner, John M. Leong, and Beth A. McCormick

Publications from 2017

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Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease, Shashi Bala, Timea Csak, Karen Kodys, Donna Catalano, Aditya Ambade, Istvan Furi, Patrick Lowe, Yeonhee Cho, Arvin Iracheta-Vellve, and Gyongyi Szabo

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Local neuropeptide signaling modulates serotonergic transmission to shape the temporal organization of C. elegans egg-laying behavior, Navonil Banerjee, Raja Bhattacharya, Michael Gorczyca, Kevin M. Collins, and Michael M. Francis

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Excitatory neurons sculpt GABAergic neuronal connectivity in the C. elegans motor circuit, Belinda Barbagallo, Alison Philbrook, Denis Touroutine, Navonil Banerjee, Devyn Oliver, Christopher M. Lambert, and Michael M. Francis

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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans, Cassandra R. Blanchette, Andrea Thackeray, Paola N. Perrat, Siegfried Hekimi, and Claire Y. Benard

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Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis, Stephen M. Carpenter, Jason D. Yang, Jinhee Lee, Palmira Barreira-Silva, and Samuel M. Behar

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A Cross-Sectional Study of Dietary and Genetic Predictors of Blood Folate Levels in Healthy Young Adults, Daniel Cummings, Kevin F. Dowling, Noah J. Silverstein, Alexandra S. Tanner, Hamdi Eryilmaz, Jordan W. Smoller, and Joshua L. Roffman

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Evidence of potential bias in a comparison of beta blockers and calcium channel blockers in patients with chronic obstructive pulmonary disease and acute coronary syndrome: results of a multinational study, Yaa-Hui Dong, Matthew Alcusky, Vittorio Maio, Jun Liu, Mengdan Liu, Li-Chiu Wu, Chia-Hsuin Chang, Mei-Shu Lai, and Joshua J. Gagne

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An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5, Ly-Sha Ee, Kurtis N. McCannell, Yang Tang, Nancy Fernandes, W. Rod Hardy, Michael R. Green, Feixia Chu, and Thomas G. Fazzio

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Survivors of an Acute Coronary Syndrome With Lower Patient Activation Are More Likely to Experience Declines in Health-Related Quality of Life, Nathaniel A. K. Erskine, Barbara L. Gandek, Molly E. Waring, Rebecca L. Kinney, Darleen M. Lessard, Randolph S. Devereaux, Stavroula A. Chrysanthopoulou, Catarina I. Kiefe, and Robert J. Goldberg

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Vitiligo: Mechanistic Insights Lead to Novel Treatments, Michael L. Frisoli and John E. Harris

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Excitatory Motor Neurons are Local Central Pattern Generators in an Anatomically Compressed Motor Circuit for Reverse Locomotion [preprint], Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Taizo Kawano, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen

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Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma, Evelyn V. Santos Guerra, Chrono K. Lee, Charles A. Specht, Bhawna Yadav, Haibin Huang, Ali Akalin, Jun R. Huh, Christian Mueller, and Stuart M. Levitz

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Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons, Yuto Hasegawa, Wenjie Mao, Sucharita Saha, Georgia Gunner, Jenya Kolpakova, Gilles E. Martin, and Kensuke Futai

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Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition, Deli Hong, Terri L. Messier, Coralee E. Tye, Jason Dobson, Andrew J. Fritz, Kenneth R. Sikora, Gillian Browne, Janet L. Stein, Jane B. Lian, and Gary S. Stein

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Fluorescence polarization control for on-off switching of single molecules at cryogenic temperatures [preprint], Christiaan Hulleman, Maximiliaan Huisman, Robert Moerland, David Grünwald, Sjoerd Stallinga, and Bernd Rieger

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Hospice Use and Pain Management in Elderly Nursing Home Residents With Cancer, Jacob N. Hunnicutt, Jennifer Tjia, and Kate L. Lapane

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Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice, Arvin Iracheta-Vellve, Jan Petrasek, Benedek Gyongyosi, Shashi Bala, Timea Csak, Karen Kodys, and Gyongyi Szabo

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The Intra-S Checkpoint Responses to DNA Damage, Divya Ramalingam Iyer and Nicholas R. Rhind

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The Sodium Channel beta4 Auxiliary Subunit Selectively Controls Long-Term Depression in Core Nucleus Accumbens Medium Spiny Neurons, Xincai Ji, Sucharita Saha, Guangping Gao, Amy W. Lasek, Gregg E. Homanics, Melissa Guildford Derner, Andrew R. Tapper, and Gilles E. Martin

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Dopamine Receptors Differentially Control Binge Alcohol Drinking-Mediated Synaptic Plasticity of the Core Nucleus Accumbens Direct and Indirect Pathways, Xincai Ji, Sucharita Saha, Jenya Kolpakova, Melissa Guildford, Andrew R. Tapper, and Gilles E. Martin

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The Prevalence of Bipolar Disorders and Association With Quality of Life in a Cohort of Patients With Multiple Sclerosis, Adalia H. Jun-O'Connell, Ankur A. Butala, Idanis Berrios Morales, Nils Henninger, Kristina M. Deligiannidis, Nancy Byatt, and Carolina Ionete

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An inhibitory mono-ubiquitylation of the Drosophila initiator caspase Dronc functions in both apoptotic and non-apoptotic pathways, Hatem E. Kamber Kaya, Mark Ditzel, Pascal Meier, and Andreas Bergmann

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Alberta Stroke Program Early CT Score Infarct Location Predicts Outcome Following M2 Occlusion, Muhib Khan, Grayson L. Baird, Richard P. Goddeau, Brian Silver, and Nils Henninger

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Leukoaraiosis, intracerebral hemorrhage, and functional outcome after acute stroke thrombolysis, Kannikar Kongbunkiat, Duncan Wilson, Narongrit Kasemsap, Somsak Tiamkao, Fatima Jichi, Vanessa Palumbo, Michael D. Hill, Alastair M. Buchan, Simon Jung, Heinrich P. Mattle, Nils Henninger, and David J. Werring

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Factors Associated with the Use of Hyaluronic Acid and Corticosteroid Injections among Patients with Radiographically Confirmed Knee Osteoarthritis: A Retrospective Data Analysis, Kate L. Lapane, Shao-Hsien Liu, Catherine E. Dube, Jeffrey B. Driban, Timothy E. McAlindon, and Charles B. Eaton

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Methods to investigate the structure and connectivity of the nervous system, Donghyung Lee, Ting-Hao Huang, Aubrie De La Cruz, Antuca Callejas, and Carlos Lois

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Patterns of intra-articular injection use after initiation of treatment in patients with knee osteoarthritis: data from the osteoarthritis initiative, Shao-Hsien Liu, Catherine E. Dube, Jeffrey B. Driban, Timothy McAlindon, Charles B. Eaton, and Kate L. Lapane

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Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice, Patrick Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Aditya Ambade, Karen Kodys, Donna Catalano, Doyle V. Ward, and Gyongyi Szabo

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Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling, Tsai-Yi Lu, Jennifer M. MacDonald, Lukas J. Neukomm, Amy E. Sheehan, Rachel Bradshaw, Mary A. Logan, and Marc R. Freeman

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The p150N domain of chromatin assembly factor-1 regulates Ki-67 accumulation on the mitotic perichromosomal layer, Timothy D. Matheson and Paul D. Kaufman

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Dynamic Control of Dendritic mRNA Expression by CNOT7 Regulates Synaptic Efficacy and Higher Cognitive Function, Rhonda L. McFleder, Fernanda Mansur, and Joel D. Richter

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Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells, Jose Mercado-Matos, Jennifer L. Clark, Andrew J. Piper, Jenny Janusis, and Leslie M. Shaw

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Histone deacetylase 1 and 2 are essential for murine neural crest proliferation, pharyngeal arch development and craniofacial morphogenesis., Zachary J. Milstone, Grace Lawson, and Chinmay M. Trivedi

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Anxiety and Nicotine Dependence: Emerging Role of the Habenulo-Interpeduncular Axis, Susanna Molas-Casacuberta, Steven Degroot, Rubing Zhao-Shea, and Andrew R. Tapper

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A circuit-based mechanism underlying familiarity signaling and the preference for novelty, Susanna Molas-Casacuberta, Rubing Zhao-Shea, Liwang Liu, Steven Degroot, Paul D. Gardner, and Andrew R. Tapper

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ICU Admission Source as a Predictor of Mortality for Patients With Sepsis, Christine A. Motzkus, Stavroula A. Chrysanthopoulou, Roger Luckmann, Teresa A. Rincon, Kate L. Lapane, and Craig M. Lilly

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Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly, Lukas J. Neukomm, Thomas C. Burdett, Andrew M. Seeds, Stefanie Hampel, Jaeda Coutinho-Budd, Jonathan E. Farley, Jack Wong, Yonca B. Karadeniz, Jeannette M. Osterloh, Amy E. Sheehan, and Marc R. Freeman

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Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope, InYoung Song, Anna Gil, Rabinarayan Mishra, Dario Ghersi, Liisa K. Selin, and Lawrence J. Stern

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Is low iodine a risk factor for cardiovascular disease in Americans without thyroid dysfunction? Findings from NHANES, Hoang V. Tran, Nathaniel A. K. Erskine, Catarina I. Kiefe, Bruce A. Barton, Kate L. Lapane, V. T. H. Do, and Robert J. Goldberg

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Depression and cognitive impairment among newly admitted nursing home residents in the USA, Christine M. Ulbricht, Anthony J. Rothschild, Jacob N. Hunnicutt, and Kate L. Lapane

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Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring, Markus P. Vallaster, Shweta Kukreja, Xin Y. Bing, Jennifer Ngolab, Rubing Zhao-Shea, Paul D. Gardner, Andrew R. Tapper, and Oliver J. Rando

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A microglia-cytokine axis to modulate synaptic connectivity and function, Sebastian Werneburg, Philip A. Feinberg, Kasey M. Johnson, and Dorothy P. Schafer

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The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach, Sijia Wu, Rita R. Fagan, Chayasith Uttamapinant, Lawrence M. Lifshitz, Kevin E. Fogarty, Alice Y. Ting, and Haley Melikian

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Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer, Sayyed K. Zaidi, Seth E. Frietze, Jonathan A. Gordon, Jessica L. Heath, Terri Messier, Deli Hong, Joseph R. Boyd, Mingu Kang, Anthony N. Imbalzano, Jane B. Lian, Janet L. Stein, and Gary S. Stein

Publications from 2016

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The promise of telecommunication tools to 'reach' the disengaged patient with diabetes, Daniel J. Amante and Michael J. Thompson

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Memory-Relevant Mushroom Body Output Synapses Are Cholinergic, Oliver Barnstedt, David Owald, Johannes Felsenberg, Ruth Brain, John-Paul Moszynski, Clifford B. Talbot, Paola N. Perrat, and Scott Waddell

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Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines, Johannes Boltze, Daniel-Christoph Wagner, Nils Henninger, Nikolaus Plesnila, and Cenk Ayata

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Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice, Terence N. Bukong, Arvin Iracheta-Vellve, Benedek Gyongyosi, Aditya Ambade, Donna Catalano, Karen Kodys, and Gyongyi Szabo

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Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease, Terence N. Bukong, Arvin Iracheta-Vellve, Banishree Saha, Aditya Ambade, Abhishek Satishchandran, Benedek Gyongyosi, Patrick Lowe, Donna Catalano, Karen Kodys, and Gyongyi Szabo

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Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice, Michael I. Carr, Justine E. Roderick, Hong Zhang, Bruce A. Woda, Michelle A. Kelliher, and Stephen N. Jones

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Phase-Variable Heptose I Glycan Extensions Modulate Efficacy of 2C7 Vaccine Antibody Directed against Neisseria gonorrhoeae Lipooligosaccharide, Srinjoy Chakraborti, Lisa A. Lewis, Andrew D. Cox, Frank St. Michael, Jianjun Li, Peter A. Rice, and Sanjay Ram

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Drosophila Vision Depends on Carcinine Uptake by an Organic Cation Transporter, Ratna Chaturvedi, Zhuo Luan, Peiyi Guo, and Hong-Sheng Li

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Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001, Matthew R. Costa, Justin Pollara, Regina Whitney Edwards, Michael S. Seaman, Miroslaw K. Gorny, David C. Montefiori, Hua-Xin Liao, Guido Ferrari, Shan Lu, and Shixia Wang

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Improving Rates of Influenza Vaccination Through Electronic Health Record Portal Messages, Interactive Voice Recognition Calls and Patient-Enabled Electronic Health Record Updates: Protocol for a Randomized Controlled Trial, Sarah L. Cutrona, Meera Sreedhara, Sarah L. Goff, Lloyd D. Fisher, Peggy Preusse, Madeline Jackson, Devi Sundaresan, Lawrence D. Garber, and Kathleen M. Mazor

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Modulation of ethanol reward sensitivity by nicotinic acetylcholine receptors containing the alpha6 subunit, Melissa Guildford Derner, Anthony V. Sacino, and Andrew R. Tapper

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New Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for Influenza, Priyadharshini Devarajan, Bianca L. Bautista, Allen M. Vong, K. Kai McKinstry, Tara M. Strutt, and Susan L. Swain

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Functional status predicts postoperative mortality after liver transplantation, Natasha H. Dolgin, Paulo N.A. Martins, Babak Movahedi, Kate L. Lapane, Frederick A. Anderson Jr., and Adel Bozorgzadeh

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Decade-Long Trends in Liver Transplant Waitlist Removal Due to Illness Severity: The Impact of Centers for Medicare and Medicaid Services Policy, Natasha H. Dolgin, Babak Movahedi, Paulo N.A. Martins, Robert J. Goldberg, Kate L. Lapane, Frederick A. Anderson Jr., and Adel Bozorgzadeh

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The Secret Life of Tethers: The Role of Tethering Factors in SNARE Complex Regulation, Michelle L. Dubuke and Mary Munson

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A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site, Caroline M. Duffy, Brendan J. Hilbert, and Brian A. Kelch

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Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance, Randall H. Friedline, Hwi Jin Ko, Dae Young Jung, Yongjin Lee, Rita Bortell, Sezin Dagdeviren, Payal R. Patel, Xiaodi Hu, Kunikazu Inashima, Caitlyn C. Kearns, Nicholas Tsitsilianos, Umber Shafiq, Dale L. Greiner, and Jason K. Kim

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Microglia: Architects of the Developing Nervous System, Jeffrey L. Frost and Dorothy P. Schafer

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Sexual Dimorphism in Alcohol Induced Adipose Inflammation Relates to Liver Injury, Melissa A. Fulham and Pranoti Mandrekar

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Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion, Daniel Tianfang Ge, Cindy Tipping, Michael H. Brodsky, and Phillip D. Zamore

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Expansion of the Knockdown Resistance Frequency Map for Human Head Lice (Phthiraptera: Pediculidae) in the United States Using Quantitative Sequencing, Kyle J. Gellatly, Sarah Krim, Daniel J. Palenchar, Katie Shepherd, Kyong Sup Yoon, Christopher J. Rhodes, Si Hyeock Lee, and J. Marshall Clark