Since the school's inception in 1979, students in the Morningside Graduate School of Biomedical Sciences at UMass Chan Medical School have contributed thousands of research publications to the field of biomedical sciences. This collection makes this body of work accessible to our students, faculty, potential recruits, the citizens of Massachusetts, and the world.

Attention students: Click on Submit Research in the left sidebar to submit your journal articles, posters, and presentations, after reviewing the Submission Guidelines. (Theses and dissertations should be submitted to Dissertations and Theses). You’ll need to log in or create a free account. If your publication appears in PubMed, you can enter the PubMed ID and information from PubMed will be used to populate the submission form. Questions? Contact escholarship@umassmed.edu.

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Publications from 2019

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Polymodal Nociception in Drosophila Requires Alternative Splicing of TrpA1, Pengyu Gu, Jiaxin Gong, Ye Shang, Fei Wang, Kendra Takle, Zhiguo Ma, Amy E. Sheehan, Marc R. Freeman, and Yang Xiang

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Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition, Reka A. Haraszti, Rachael Miller, Michelle L. Dubuke, Andrew H. Coles, Marie C. Didiot, Dimas Echeverria, Matteo Stoppato, Yves Y. Sere, John D. Leszyk, Julia F. Alterman, Bruno M. D. C. Godinho, Matthew R. Hassler, Rachel Wollacott, Yan Wang, Scott A. Shaffer, Neil Aronin, and Anastasia Khvorova

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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity, Anne Margriet Heijink, Marieke Everts, Megan E. Honeywell, Ryan Richards, Yannick P. Kok, Elisabeth G. E. de Vries, Michael J. Lee, and Marcel A T M van Vugt

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De Novo Lipogenesis as a Source of Second Messengers in Adipocytes, Wen-Yu Hsiao and David A. Guertin

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Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes, Robert J. Ihry, Zinger Yang, and Ajamete Kaykas

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Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans, Orkan Ilbay and Victor R. Ambros

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A DNA-guided Argonaute Protein Functions in DNA Replication in Thermus thermophilus [preprint], Samson M. Jolly, Ildar Gainetdinov, , Han Zhang, Lara Strittmatter, Gregory M. Hendricks, Avantika Dhabaria, Beatrix Ueberheide, and Phillip D. Zamore

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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1, Su Myung Jung, Chien-Min Hung, Samuel R. Hildebrand, Joan Sanchez-Gurmaches, Dimpi Mukhopadhyay, Camila Martinez Calejman, Amelia K. Luciano, Wen-Yu Hsiao, Yuefeng Tang, Huawei Li, and David A. Guertin

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Cyclophilin A protects HIV-1 from restriction by human TRIM5alpha, Kyusik Kim, Ann Dauphin, Sevnur Komurlu, Sean M. McCauley, Leonid Yurkovetskiy, Claudia Carbone, William E. Diehl, Caterina Strambio-De-Castillia, Edward M. Campbell, and Jeremy Luban

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Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved AS-NMD pathways [preprint], Carrie Kovalak, Mihir Metkar, and Melissa J. Moore

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Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes, Suet-Yan Kwan, Ankur Sheel, Chun-Qing Song, Xiao-Ou Zhang, Tingting Jiang, Hien Dang, Yueying Cao, Deniz M. Ozata, Haiwei Mou, Hao Yin, Zhiping Weng, Xin Wei Wang, and Wen Xue

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Tissue-specific Genome Editing in vivo by MicroRNA-repressible Anti-CRISPR Proteins [preprint], Jooyoung Lee, Haiwei Mou, Raed Ibraheim, Shun-Qing Liang, Wen Xue, and Erik J. Sontheimer

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Emergency Department and Primary Care Use in Massachusetts 5 Years After Health Reform, Lisa M. Lines, Nien-Chen Li, Eric O. Mick, and Arlene S. Ash

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Association between emotional eating, energy-dense foods and overeating in Latinos, Andrea Lopez-Cepero, Christine F. Frisard, Stephenie C. Lemon, and Milagros C. Rosal

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Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals, Nicole Lowres, David D. McManus, and Apurv Soni

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Racial Segregation Across U.S. Nursing Homes: A Systematic Review of Measurement and Outcomes, Deborah Mack, William M. Jesdale, Christine M. Ulbricht, Sarah N. Forrester, Pryce S. Michener, and Kate L. Lapane

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Screening Mammography Among Older Women: A Review of United States Guidelines and Potential Harms, Deborah S. Mack and Kate L. Lapane

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Positive screening rates for bipolar disorder in pregnant and postpartum women and associated risk factors, Grace A. Masters, Linda Brenckle, Padma Sankaran, Sharina D. Person, Jeroan J. Allison, Tiffany A. Moore Simas, Jean Y. Ko, Cheryl L. Robbins, Wendy K. Marsh, and Nancy Byatt

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BarkBase: Epigenomic Annotation of Canine Genomes, Kate Megquier, Xue Li, Kathleen Morrill, Brittney Logan, and Elinor K. Karlsson

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Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells, So Yun Min, Anand Desai, Zinger Yang, Agastya Sharma, Tiffany DeSouza, Ryan Genga, Alper Kucukural, Lawrence M. Lifshitz, Soren Nielsen, Camilla Scheele, Rene Maehr, Manuel Garber, and Silvia Corvera

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Exercise Rescues Gene Pathways Involved in Vascular Expansion and Promotes Functional Angiogenesis in Subcutaneous White Adipose Tissue, So Yun Min, Heather Learnard, Shashi Kant, Olga Gaelikman, Raziel Rojas-Rodriguez, Tiffany DeSouza, Anand Desai, John F. Keaney Jr., Silvia Corvera, and Siobhan M. Craige

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The PRogram In Support of Moms (PRISM): study protocol for a cluster randomized controlled trial of two active interventions addressing perinatal depression in obstetric settings, Tiffany A. Moore Simas, Linda Brenckle, Padma Sankaran, Grace A. Masters, Sharina D. Person, Linda Weinreb, Jean Y. Ko, Cheryl L. Robbins, Jeroan J. Allison, and Nancy Byatt

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A Novel PHOX/CD38/MCOLN1/TFEB Axis Important For Macrophage Activation During Bacterial Phagocytosis [preprint], Mehran Najibi, Joseph A. Moreau, Havisha H. Honwad, and Javier E. Irazoqui

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TRIM34 acts with TRIM5 to restrict HIV and SIV capsids [preprint], Molly Ohainle, Kyusik Kim, Sevnur Keceli, Abby Felton, Ed Campbell, Jeremy Luban, and Michael Emerman

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Co-option of the gibbon-specific LAVA retrotransposon in DNA repair pathways [preprint], Mariam Okhovat, Kimberly A. Nevonen, Brett Davis, Pryce S. Michener, Samantha Ward, Mark Milhaven, Lana Harshman, Ajuni Sohota, Rachel J. O’Neill, Nadav Ahituv, Krishna R. Veeramah, and Lucia Carbone

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Integrins Have Cell-Type-Specific Roles in the Development of Motor Neuron Connectivity, Devyn Oliver, Emily Norman, Heather Bates, Rachel Avard, Monika Rettler, Claire Y. Benard, Michael M. Francis, and Michele L. Lemons

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Cilia in cystic kidney and other diseases, Gregory J. Pazour, Lynne Quarmby, Abigail O. Smith, Paurav B. Desai, and Miriam Schmidts

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The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans, Nicholas D. Peterson, Hilary K. Cheesman, Pengpeng Liu, Sarah M. Anderson, Kyle J. Foster, Richa Chhaya, Paola N. Perrat, Jose Thekkiniath, Qiyuan Yang, Cole M. Haynes, and Read Pukkila-Worley

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Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC), Andrew J. Piper, Jennifer L. Clark, Jose R. Mercado-Matos, Asia N. Matthew-Onabanjo, Chung-Cheng Hsieh, Ali Akalin, and Leslie M. Shaw

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Insomnia in patients with schizophrenia: current understanding and treatment options, Ian Robertson, Amy Cheung, and Xiaoduo Fan

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Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis, Banishree Saha, David Tornai, Karen Kodys, Adeyinka Adejumo, Patrick P. Lowe, Craig McClain, Mack Mitchell, Arthur McCullough, Srinivasan Dasarathy, Aimee Kroll-Desrosiers, Bruce A. Barton, Svetlana Radaeva, and Gyongyi Szabo

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Phosphorylation on PstP controls cell wall metabolism and antibiotic tolerance in Mycobacterium smegmatis [preprint], Farah Shamma, Kadamba Papavinasasundaram, Aditya Bandekar, Christopher M. Sassetti, and Cara C. Boutte

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Atf6alpha impacts cell number by influencing survival, death and proliferation, Rohit B. Sharma, Jarin T. Snyder, and Laura C. Alonso

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Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange, Raushan K. Singh, Jiayi Fan, Nathan Gioacchini, Shinya Watanabe, Osman Bilsel, and Craig L. Peterson

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An automated Bayesian pipeline for rapid analysis of single-molecule binding data, Carlas Smith, Karina Jouravleva, Maximiliaan Huisman, Samson M. Jolly, Phillip D. Zamore, and David Grünwald

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The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration, Yuanquan Song, Fei Wang, Jiaxin Gong, Yang Xiang, and Yuh Nung Jan

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Healthy Eating Policy Strategies in Community Health Improvement Plans: A Cross-Sectional Survey of US Local Health Departments, Meera Sreedhara, Karin V. Goins, Christine F. Frisard, Milagros C. Rosal, and Stephenie C. Lemon

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Stepping Up Active Transportation in Community Health Improvement Plans: Findings From a National Probability Survey of Local Health Departments, Meera Sreedhara, Karin V. Goins, Christine F. Frisard, Milagros C. Rosal, and Stephenie C. Lemon

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TALE and NF-Y co-occupancy marks enhancers of developmental control genes during zygotic genome activation in zebrafish [preprint], William J. Stanney III, Franck Ladam, Ian J. Donaldson, Teagan J. Parsons, Rene Maehr, Nicoletta Bobola, and Charles G. Sagerstrom

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Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure, Nicholas P. Stone, Gabriel Demo, Emily Agnello, and Brian A. Kelch

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Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function [preprint], Carolyn G. Sweeney, Patrick Kearney, Rita R. Fagan, Lindsey A. Smith, Nicholas C. Bolden, Rubing Zhao-Shea, Iris V. Rivera, Jenya Kolpakova, Jun Xie, Guangping Gao, Andrew R. Tapper, Gilles E. Martin, and Haley Melikian

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Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function, Carolyn G. Sweeney, Patrick J. Kearney, Rita R. Fagan, Lindsey A. Smith, Nicholas C. Bolden, Rubing Zhao-Shea, Iris V. Rivera, Jenya Kolpakova, Jun Xie, Guangping Gao, Andrew R. Tapper, Gilles E. Martin, and Haley Melikian

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Molecular and structural mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir [preprint], Jennifer Timm, Klajdi Kosovrasti, Mina Henes, Florian Leidner, Shurong Hou, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing, Maeve Tischbein, Desiree M. Baron, Yen-Chen Lin, Katherine V. Gall, John E. Landers, Claudia Fallini, and Daryl A. Bosco

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Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast, Salih Topal, Pauline Vasseur, Marta Radman-Livaja, and Craig L. Peterson

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Impact of anxiety on the post-discharge outcomes of patients discharged from the hospital after an acute coronary syndrome, Hoang Tran, Nancy Byatt, Nathaniel A. K. Erskine, Darleen M. Lessard, Randolph S. Devereaux, Jane Saczynski, Catarina I. Kiefe, and Robert J. Goldberg

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Micro-RNAs Are Related to Epicardial Adipose Tissue in Participants With Atrial Fibrillation: Data From the MiRhythm Study, Khanh-Van T. Tran, Jordan Majka, Saket Sanghai, Mayank Sardana, Darleen M. Lessard, Zachary J. Milstone, Kahraman Tanriverdi, Jane E. Freedman, Timothy P. Fitzgibbons, and David D. McManus

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Circulating extracellular RNAs, myocardial remodeling, and heart failure in patients with acute coronary syndrome, Khanh-Van T. Tran, Kahraman Tanriverdi, Gerard P. Aurigemma, Darleen M. Lessard, Mayank Sardana, Matthew Parker, Amir Y. Shaikh, Matthew Gottbrecht, Zachary Milstone, Selim E. Tanriverdi, Olga Vitseva, John F. Keaney Jr., Catarina I. Kiefe, David D. McManus, and Jane E. Freedman

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Differential expression of neurexin genes in the mouse brain, Motokazu Uchigashima, Amy Cheung, Julie Suh, Masahiko Watanabe, and Kensuke Futai

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Non-malignant pain symptom subgroups in nursing home residents, Christine M. Ulbricht, Jacob N. Hunnicutt, Giovanni Gambassi, Anne L. Hume, and Kate L. Lapane

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Nervous system control of intestinal host defense in C. elegans, Khursheed A. Wani, Debanjan Goswamy, and Javier E. Irazoqui

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Evaluation of IL-1 blockade as a host-directed therapy for tuberculosis in mice and macaques [preprint], Caylin G. Winchell, Bibhuti B. Mishra, University of Massachusetts Medical School, Samantha J. Nelson, Christopher M. Sassetti, and JoAnne L. Flynn

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Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain, Ozge Yildiz, Gerald B. Downes, and Charles G. Sagerstrom

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Nursing Home Star Ratings and New Onset of Depression in Long-Stay Nursing Home Residents, Yiyang Yuan, Kate L. Lapane, Jonggyu Baek, William M. Jesdale, and Christine M. Ulbricht

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The piRNA Response to Retroviral Invasion of the Koala Genome, Tianxiong Yu, Birgit S. Koppetsch, Sara Pagliarani, Stephen Johnston, Noah J. Silverstein, Jeremy Luban, Keith Chappell, Zhiping Weng, and William E. Theurkauf

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A Delicate Balance between Bacterial Iron and Reactive Oxygen Species Supports Optimal C. elegans Development, Jingyan Zhang, Xuhang Li, Maria Olmedo, Amy D. Holdorf, Ye Shang, Marta Artal-Sanz, L. Safak Yilmaz, and Albertha J. M. Walhout (Cell host and microbe, 2019-09-11)

Publications from 2018

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Hypertension knowledge, heart healthy lifestyle practices and medication adherence among adults with hypertension, Hawa Ozien Abu, Hanan Aboumatar, Kathryn Carson, Robert J. Goldberg, and Lisa Cooper

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Are we “missing the big picture” in transitions of care? Perspectives of healthcare providers managing patients with unplanned hospitalization, Hawa Ozien Abu, Milena D. Anatchkova, Nathaniel A. K. Erskine, Joanne Lewis, David D. McManus, Catarina I. Kiefe, and Heena P. Santry

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Association of religiosity and spirituality with quality of life in patients with cardiovascular disease: a systematic review, Hawa Abu, Christine M. Ulbricht, Eric Y. Ding, Jeroan J. Allison, Elena Salmoirago-Blotcher, Robert J. Goldberg, and Catarina I. Kiefe

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TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis, Diwash Acharya, Bernadette Nera, Zachary J. Milstone, Lauren Bourke, Yeonsoo Yoon, Jaime A. Rivera-Pérez, Chinmay M. Trivedi, and Thomas G. Fazzio

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Treatment of atrial fibrillation in nursing homes: A place for direct acting oral anticoagulants, Matthew Alcusky and Kate L. Lapane

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NmeCas9 is an intrinsically high-fidelity genome-editing platform, Nadia Amrani, Xin D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Raed Ibraheim, Ankit Gupta, Kanae E. Sasaki, Tong Wu, Thomas G. Fazzio, Lihua Julie Zhu, Scot A. Wolfe, and Erik J. Sontheimer

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Breakdown of Neural Function under Isoflurane Anesthesia: In Vivo, Multineuronal Imaging in Caenorhabditis elegans, Mehraj R. Awal, Doug Austin, Jeremy Florman, Mark J. Alkema, Christopher V. Gabel, and Christopher W. Connor

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Role of the MAPK/cJun NH2-Terminal Kinase signaling pathway in starvation-induced autophagy, Seda Barutcu, Nomeda Girnius, Santiago Vernia, and Roger J. Davis

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Assembly of human C-terminal binding protein (CtBP) into tetramers, Andrew G. Bellesis, Anne M. Jecrois, Janelle A. Hayes, Celia A. Schiffer, and William E. Royer

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Hydrophobicity of Lipid-Conjugated siRNAs Predicts Productive Loading to Small Extracellular Vesicles, Annabelle Biscans, Reka A. Haraszti, Dimas Echeverria, Rachael Miller, Marie C. Didiot, Mehran Nikan, Loic Roux, Neil Aronin, and Anastasia Khvorova

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Can Mindfulness Address Maladaptive Eating Behaviors? Why Traditional Diet Plans Fail and How New Mechanistic Insights May Lead to Novel Interventions, Judson A. Brewer, Andrea Ruf, Ariel Beccia, Gloria I. Essien, Leonard M. Finn, Remko van Lutterveld, and Ashley E. Mason

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A Persistence Detector for Metabolic Network Rewiring in an Animal [preprint], Jote T. Bulcha, Gabrielle E. Giese, Zulfikar Ali, Yong-Uk Lee, Melissa D. Walker, Amy D. Holdorf, L. Safak Yilmaz, Robert C. Brewster, and Albertha J. M. Walhout

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Maelstrom Represses Canonical Polymerase II Transcription within Bi-directional piRNA Clusters in Drosophila melanogaster, Timothy Chang, Eugenio Mattei, Ildar Gainetdinov, Cansu Colpan, Zhiping Weng, and Phillip D. Zamore

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Focal adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior, Sukhee Cho, Allie Muthukumar, Tobias Stork, Jaeda C. Coutinho-Budd, and Marc R. Freeman

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Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin, Marie C. Didiot, Chantal M. Ferguson, Socheata Ly, Andrew H. Coles, Abigail O. Smith, Alicia A. Bicknell, Lauren M. Hall, Ellen Sapp, Dimas Echeverria, Athma A. Pai, Marian DiFiglia, Melissa J. Moore, Lawrence J. Hayward, Neil Aronin, and Anastasia Khvorova

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Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans, Gregoriy A. Dokshin, Krishna S. Ghanta, Katherine M. Piscopo, and Craig C. Mello

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Association Between Sarcopenia and Functional Status in Liver Transplant Patients, Natasha H. Dolgin, Andrew J. Smith, Samantha G. Harrington, Babak Movahedi, Paulo N.A. Martins, and Adel Bozorgzadeh

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Cognitive Impairment and Pain Among Nursing Home Residents With Cancer, Catherine E. Dube, Deborah Mack, Jacob N. Hunnicutt, and Kate L. Lapane

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VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP beta2-chimaerin, Ameer L. Elaimy, Santosh Guru, Cheng Chang, Jianhong Ou, John J. Amante, Lihua Julie Zhu, Hira Lal Goel, and Arthur M. Mercurio

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Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2, Roland Elling, Zhaozhao Jiang, Shiuli Agarwal, Mona Motwani, Jennie Chan, Shrutie Sharma, Katherine A. Fitzgerald, and Susan Carpenter

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Barriers to Healthcare Access and to Improvements in Health-Related Quality of Life After an Acute Coronary Syndrome (From TRACE-CORE), Nathaniel A. K. Erskine, Barbara L. Gandek, Hoang V. Tran, Hawa Ozien Abu, David D. McManus, Catarina I. Kiefe, and Robert J. Goldberg

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Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration, Jonathan E. Farley, Thomas C. Burdett, Romina Barria, Lukas J. Neukomm, Kevin P. Kenna, John E. Landers, and Marc R. Freeman

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Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila, Pooja Flora, Sean Schowalter, SiuWah Wong-Deyrup, Matthew DeGennaro, Mohamad Ali Nasrallah, and Prashanth Rangan

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Peptide Antigen Concentration Modulates Digital NFAT1 Activation in Primary Mouse Naive CD8(+) T Cells as Measured by Flow Cytometry of Isolated Cell Nuclei, Michael P. Gallagher, James M. Conley, and Leslie J. Berg

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Excitatory motor neurons are local oscillators for backward locomotion, Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Taizo Kawano, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen

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The molecular interplay between axon degeneration and regeneration, Marie-Pier Girouard, Mardja Bueno, Victoria Julian, Sienna Drake, Alexandra B. Byrne, and Alyson E. Fournier

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Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory, Alden L. Gross, Doug Tommet, Madeline D'Aquila, Eva Schmitt, Edward R. Marcantonio, Benjamin Helfand, Sharon K. Inouye, and Richard N. Jones

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SeekDeep: single-base resolution de novo clustering for amplicon deep sequencing, Nicholas J. Hathaway, Christian M. Parobek, Jonathan J. Juliano, and Jeffrey A. Bailey

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Racial/ethnic representation in lifestyle weight loss intervention studies in the United States: A systematic review, Christina Haughton, Valerie J. Silfee, Monica L. Wang, Andrea Lopez-Cepero, David P. Estabrook, Christine F. Frisard, Milagros C. Rosal, Sherry L. Pagoto, and Stephenie C. Lemon

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Structural analysis of the active site and DNA binding of human cytidine deaminase APOBEC3B, Shurong Hou, Tania V. Silvas, Florian Leidner, Ellen A. Nalivaika, Hiroshi Matsuo, Nese Kurt Yilmaz, and Celia A. Schiffer

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Fluorescence Polarization Control for On-Off Switching of Single Molecules at Cryogenic Temperatures, Christiaan N. Hulleman, Maximiliaan Huisman, Robert J. Moerland, David Grünwald, Sjoerd Stallinga, and Bernd Rieger

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Commonly Initiated Opioids and Risk of Fracture Hospitalizations in United States Nursing Homes, Jacob N. Hunnicutt, Anne L. Hume, Shao-Hsien Liu, Christine M. Ulbricht, Jennifer Tjia, and Kate L. Lapane

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All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo, Raed Ibraheim, Chun-Qing Song, Aamir Mir, Nadia Amrani, Wen Xue, and Erik J. Sontheimer

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FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice, Arvin Iracheta-Vellve, Charles D. Calenda, Jan Petrasek, Aditya Ambade, Karen Kodys, Luciano Adorini, and Gyongyi Szabo

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Prognostic role of elevated mir-24-3p in breast cancer and its association with the metastatic process, Alireza Khodadadi-Jamayran, Betul Akgol-Oksuz, Yelena Afanasyeva, Adriana Heguy, Marae Thompson, Karina Ray, Ariadna Giro-Perafita, Irma Sanchez, Xifeng Wu, Debu Tripathy, Anne Zeleniuch-Jacquotte, Aristotelis Tsirigos, and Francisco J. Esteva

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Understanding the Digital Gap Among US Adults With Disability: Cross-Sectional Analysis of the Health Information National Trends Survey 2013, Eun Ji Kim, Yiyang Yuan, Jane Liebschutz, Howard Cabral, and Lewis Kazis

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Neural Network Interactions Modulate CRY-Dependent Photoresponses in Drosophila, Pallavi Lamba, Lauren E. Foley, and Patrick Emery

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Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins, Jooyoung Lee, Aamir Mir, Alireza Edraki, Bianca Garcia, Nadia Amrani, Hannah E. Lou, Ildar Gainetdinov, April Pawluk, Raed Ibraheim, Xin D. Gao, Pengpeng Liu, Alan R. Davidson, Karen L. Maxwell, and Erik J. Sontheimer

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Association Between Obstetric Provider's Advice and Gestational Weight Gain, Andrea Lopez-Cepero, Katherine Leung, Tiffany A. Moore Simas, and Milagros C. Rosal

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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression, Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Yeonhee Cho, Aditya Ambade, and Gyongyi Szabo

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Non-Hispanic Black-White disparities in pain and pain management among newly admitted nursing home residents with cancer, Deborah Mack, Jacob N. Hunnicutt, William M. Jesdale, and Kate L. Lapane

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Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1, Wenjie Mao, Anna C. Salzberg, Motokazu Uchigashima, Yuto Hasegawa, Hanno Hock, Masahiko Watanabe, Schahram Akbarian, Yuka Imamura. Kawasawa, and Kensuke Futai

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Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease, Ashley N. Matthew, Florian Leidner, Alicia Newton, Christos J. Petropoulos, Wei Huang, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines, Sean M. McCauley, Kyusik Kim, Anetta Nowosielska, Ann Dauphin, Leonid Yurkovetskiy, William E. Diehl, and Jeremy Luban