Since the school's inception in 1979, students in the Graduate School of Biomedical Sciences (GSBS) have contributed thousands of research publications to the field of biomedical sciences. The GSBS Student Publications collection makes this body of work accessible to our students, faculty, potential recruits, and the citizens of Massachusetts.

Attention GSBS students: Click on Submit Research in the left sidebar to submit your journal articles, posters, and presentations, after reviewing the Submission Guidelines. (Theses and dissertations should be submitted to GSBS Dissertations and Theses). You’ll need to log in or create a free account. If your publication appears in PubMed, you can enter the PubMed ID and information from PubMed will be used to populate the submission form. Questions? Contact escholarship@umassmed.edu.

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Publications from 2020

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Midbrain Dopamine Controls Anxiety-like Behavior by Engaging Unique Interpeduncular Nucleus Microcircuitry, Steven R. DeGroot, Rubing Zhao-Shea, Leeyup Chung, Paul M. Klenowski, Fangmiao Sun, Susanna Molas-Casacuberta, Paul D. Gardner, Yulong Li, and Andrew R. Tapper

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BCL11A enhancer edited hematopoietic stem cells persist in rhesus monkeys without toxicity, Selami Demirci, Jing Zeng, Yuxuan Wu, Naoya Uchida, Anne H. Shen, Danilo Pellin, Jackson Gamer, Morgan Yapundich, Claire Drysdale, Jasmine Bonanno, Aylin C. Bonifacino, Allen Krouse, Nathaniel Seth. Linde, Theresa Engels, Robert E. Donahue, Juan J. Haro-Mora, Alexis Leonard, Tina Nassehi, Kevin Luk, Shaina N. Porter, Cicera R. Lazzarotto, Shengdar Q. Tsai, Mitchell Weiss, Shondra M. Pruett-Miller, Scot A. Wolfe, Daniel E. Bauer, and John F. Tisdale

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CD4 Effectors Need to Recognize Antigen Locally to Become Cytotoxic CD4 and Follicular Helper T Cells [preprint], Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Bianca L. Bautista, Michael C. Jones, Olivia Kugler-Umana, Karen A. Kelly, and Susan L. Swain

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Engineering essential genes with a "jump board" strategy using CRISPR/Cas9, Ye Duan, Sungwook Choi, Charles Nelson, and Victor R. Ambros

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RNA-seq with RNase H-based ribosomal RNA depletion specifically designed for C. elegans, Ye Duan, Yongming Sun, and Victor R. Ambros

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Expanded encyclopaedias of DNA elements in the human and mouse genomes, ENCODE Project Consortium, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, Xiao-Ou Zhang, Shaimae I. Elhajjajy, Jack Huey, Job Dekker, J. Michael Cherry, Richard M. Myers, Bing Ren, Brenton R. Graveley, Mark B. Gerstein, Len A. Pennacchio, Michael P. Snyder, Bradley E. Bernstein, Barbara Wold, Ross C. Hardison, Thomas R. Gingeras, John A. Stamatoyannopoulos, and Zhiping Weng

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In Situ Regulated Dopamine Transporter Trafficking: There's No Place Like Home, Rita R. Fagan, Patrick J. Kearney, and Haley E. Melikian

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Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact, Rita R. Fagan, Patrick Kearney, Carolyn G. Sweeney, Dino Luethi, Florianne E. Schoot Uiterkamp, Klaus Schicker, Brian S. Alejandro, Lauren C. O'Connor, Harald H. Sitte, and Haley Melikian

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Genetic and Epigenetic Features of Promoters with Ubiquitous Chromatin Accessibility Support Ubiquitous Transcription of Cell-essential Genes [preprint], Kaili Fan, Jill E. Moore, Xiao-Ou Zhang, and Zhiping Weng

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Comparison of a Collective Intelligence Tailored Messaging System on Smoking Cessation Between African American and White People Who Smoke: Quasi-Experimental Design, Jamie Faro, Catherine S. Nagawa, Jeroan J. Allison, Stephenie C. Lemon, Kathleen M. Mazor, Thomas K. Houston, and Rajani S. Sadasivam

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The relationship of aging, complete tooth loss, and having a dental visit in the last 12 months, Andriana M. Foiles Sifuentes, Maira Castaneda-Avila, and Kate L. Lapane

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The Role of Limited English Proficiency and Access to Health Insurance and Health Care in the Affordable Care Act Era, Andriana M. Foiles Sifuentes, Monica Robledo Cornejo, Nien-Chen Li, Maira Castaneda-Avila, Jennifer Tjia, and Kate L. Lapane

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Drosophila Cryptochrome: Variations in Blue, Lauren E. Foley and Patrick Emery

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Innate Immunity in the C. elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development, Kyle J. Foster, Hilary K. Cheesman, Pengpeng Liu, Nicholas D. Peterson, Sarah M. Anderson, and Read Pukkila-Worley

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From Tank to Treatment: Modeling Melanoma in Zebrafish, William Tyler Frantz and Craig J. Ceol

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Early life lessons: The lasting effects of germline epigenetic information on organismal development, Carolina Galan, Marina Krykbaeva, and Oliver J. Rando

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Cytosine methylation dynamics during post-testicular sperm maturation in mammals [preprint], Carolina Galan, Ryan W. Serra, Fengyun Sun, Vera Rinaldi, Colin C. Conine, and Oliver J. Rando

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ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia, Kayleigh M. Gallagher, Justine E. Roderick, Shi Hao. Tan, Tze King Tan, Leonard Murphy, Jun Yu, Rui Li, Kevin O'Connor, Lihua Julie Zhu, Michael R. Green, Takaomi Sanda, and Michelle A. Kelliher

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The Tec kinase ITK differentially optimizes NFAT, NF-κB, and MAPK signaling during early T cell activation to regulate graded gene induction [preprint], Michael P. Gallagher, James M. Conley, Pranitha Vangala, Andrea Reboldi, Manuel Garber, and Leslie J. Berg

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Current Insights in Cutaneous Lupus Erythematosus Immunopathogenesis, Colton J. Garelli, Maggi Ahmed Refat, Padma P. Nanaware, Zaida G. Ramirez-Ortiz, Medhi Rashighi, and Jillian M. Richmond

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Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism [preprint], Christl Gaubitz, Xingchen Liu, Joseph Magrino, Nicholas P. Stone, Jacob Landeck, Mark Hedglin, and Brian A. Kelch

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Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in Caenorhabditis elegans, Krishna S. Ghanta and Craig C. Mello

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Melting dsDNA donor molecules potentiates precision genome editing in C. elegans [preprint], Krishna S. Ghanta and Craig C. Mello

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Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor, Gabrielle E. Giese, Melissa D. Walker, Olga Ponomarova, Hefei Zhang, Xuhang Li, Gregory Minevich, and Albertha J. M. Walhout

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Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor alpha and beta Repertoires, Anna Gil, Larisa Kamga, Ramakanth Chirravuri-Venkata, Nuray Aslan, Fransenio G. Clark, Dario Ghersi, Katherine Luzuriaga, and Liisa K. Selin

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LncRNA RP11-19E11 is an E2F1 target required for proliferation and survival of basal breast cancer, A. Giro-Perafita, L. Luo, A. Khodadadi-Jamayran, M. Thompson, Betul Akgol-Oksuz, A. Tsirigos, B. D. Dynlacht, I. Sanchez, and F. J. Esteva

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Control of Adipocyte Thermogenesis and Lipogenesis through beta3-Adrenergic and Thyroid Hormone Signal Integration, Adilson L. Guilherme, Batuhan Yenilmez, Alexander H. Bedard, Felipe Henriques, Dianxin Liu, Alexandra Lee, Lauren Goldstein, Mark Kelly, Sarah M. Nicoloro, Min Chen, Lee Weinstein, Sheila Collins, and Michael P. Czech

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Premature Atrial and Ventricular Contraction Detection using Photoplethysmographic Data from a Smartwatch, Dong Han, Syed Khairul Bashar, Fahimeh Mohagheghian, Eric Y. Ding, Cody Whitcomb, David D. McManus, and Ki H. Chon

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Reduction of Inappropriate Antibiotic Use and Improved Outcomes by Implementation of an Algorithm-Based Clinical Guideline for Nonpurulent Skin and Soft Tissue Infections, John P. Haran, Melissa Goulding, Maureen Campion, Gail Scully, Arnav Chandra, Rebecca Goldberg, Allyson Day, Emily McLendon, and Melissa A. Clark

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The Exclusion of Older Persons From Vaccine and Treatment Trials for Coronavirus Disease 2019-Missing the Target, Benjamin K.I. Helfand, Margaret Webb, Sarah L. Gartaganis, Lily Fuller, Churl-Su Kwon, and Sharon K. Inouye

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Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis, Felipe Henriques, Alexander H. Bedard, Adilson L. Guilherme, Mark Kelly, Lawrence M. Lifshitz, Karl D. Bellve, Leslie A. Rowland, Batuhan Yenilmez, Shreya Kumar, Yetao Wang, Jeremy Luban, and Michael P. Czech

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Single Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis [preprint], Felipe Henriques, Alexander H. Bedard, Adilson L. Guilherme, Mark Kelly, Lawrence M. Lifshitz, Karl D. Bellve, Leslie Rowland, Batuhan Yenilmez, Shreya Kumar, Yetao Wang, Jeremy Luban, and Michael P. Czech

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The Erythropoietin Receptor Stimulates Rapid Cycling and Formation of Larger Red Cells During Mouse and Human Erythropoiesis [preprint], Daniel Hidalgo, Jacob Bejder, Ramona Pop, Kyle Gellatly, S. Maxwell Scalf, Anna E. Eastman, Jane-Jane Chen, Lihua Julie Zhu, Jules A.A.C. Heuberger, Shangqin Guo, Mark J. Koury, Nikolai Baastrup Nordsborg, and Merav Socolovsky

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Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP, Annie Hien, Gemma Molinaro, Botao Liu, Kimberly M. Huber, and Joel D. Richter

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The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development, Wen-Yu Hsiao, Su Myung Jung, Yuefeng Tang, John A. Haley, Rui Li, Huawei Li, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Chien-Min Hung, Amelia K. Luciano, Victoria DeMambro, Kathryn E. Wellen, Clifford J. Rosen, Lihua Julie Zhu, and David A. Guertin

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Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors [preprint], Raed Ibraheim, Phillip W. L. Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomas Rodriguez, Samantha J. Nelson, Eraj Khokhar, Esther Mintzer, Stacy Maitland​, Yueying Cao, Guangping Gao, and Erik J. Sontheimer

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CryoEM Structure of CtBP2 Confirms Tetrameric Architecture [preprint], Anne M. Jecrois, M. Michael Dcona, Xiaovan Deng, Dipankar Bandyopadhyay, Steven R. Grossman, Celia A. Schiffer, and William E. Royer

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Cryo-EM Structure of CtBP2 Confirms Tetrameric Architecture, Anne M. Jecrois, M. Michael Dcona, Xiaoyan Deng, Dipankar Bandyopadhyay, Steven R. Grossman, Celia A. Schiffer, and William E. Royer Jr.

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Cancer Pain in Relation to Metropolitan Area Segregation and Nursing Home Racial and Ethnic Composition, William M. Jesdale, Deborah Mack, Sarah N. Forrester, and Kate L. Lapane

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Thermus thermophilus Argonaute Functions in the Completion of DNA Replication, Samson M. Jolly, Ildar Gainetdinov, , Han Zhang, Lara Strittmatter, Shannon M. Bailey, Gregory M. Hendricks, Avantika Dhabaria, Beatrix Ueberheide, and Phillip D. Zamore

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A highly efficient method for single-cell electroporation in mouse organotypic hippocampal slice culture, David G. Keener, Amy Cheung, and Kensuke Futai

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Single-Cell Electroporation across Different Organotypic Slice Culture of Mouse Hippocampal Excitatory and Class-Specific Inhibitory Neurons, David G. Keener, Amy Cheung, and Kensuke Futai

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Primary care physician perspectives on barriers to diagnosing axial Spondyloarthritis: a qualitative study, Kate L. Lapane, Sara Khan, Divya Shridharmurthy, Ariel Beccia, Catherine E. Dube, Esther Yi, Jonathan Kay, and Shao-Hsien Liu

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The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network, Cassandra M. Leech, Mackenzie J. Flynn, Heather E. Arsenault, Jianhong Ou, Haibo Liu, Lihua Julie Zhu, and Jennifer A. Benanti

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CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis, Jinhee Lee, Shayla Boyce, Jennifer Powers, Christina E. Baer, Christopher M. Sassetti, and Samuel M. Behar

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Physical activity and attitudes towards exercise in people with axial and peripheral spondyloarthritis, Shao-Hsien Liu, Divya Shridharmurthy, Kate L. Lapane, Catherine E. Dube, Ellen M. Gravallese, and Jonathan Kay

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Optimizing the refinement of merohedrally twinned P61 HIV-1 protease-inhibitor cocrystal structures, Gordon J. Lockbaum, Florian Leidner, William E. Royer, Nese Kurt Yilmaz, and Celia A. Schiffer

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Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1, Heather S. Loring, Janneke D. Icso, Venkatesh V. Nemmara, and Paul R. Thompson

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Identification of the first noncompetitive SARM1 inhibitors, Heather S. Loring, Sangram Parelkar, Santanu Mondal, and Paul R. Thompson

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Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases, Heather S. Loring and Paul R. Thompson

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Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM [preprint], Anna B. Loveland, Egor Svidritskiy, Denis Susorov, Soojin Lee, Alexander Park, Gabriel Demo, Fen-Biao Gao, and Andrei A. Korostelev

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Statin Discontinuation and Life-Limiting Illness in Non-Skilled Stay Nursing Homes at Admission, Deborah S. Mack, Jonggyu Baek, Jennifer Tjia, and Kate L. Lapane

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Prevalent Statin Use in Long-Stay Nursing Home Residents with Life-Limiting Illness, Deborah S. Mack, Jennifer Tjia, Anne L. Hume, and Kate L. Lapane

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Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae [preprint], Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard E. Baker, and Allan Jacobson

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Methods for detecting PER2::LUCIFERASE bioluminescence rhythms in freely moving mice [preprint], B. Martin-Burgos, W. Wang, I. William, S. Tir, I. Mohammad, R. Javed, Smith College, Y. Cui, Ciearra B. Smith, V. van der Vinne, P.C. Molyneux, Stephen C. Miller, David R. Weaver, T.L. Leise, and M.E. Harrington

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Utilization of Health Care Among Perinatal Women in the United States: The Role of Depression, Grace A. Masters, Nien-Chen Li, Kate L. Lapane, Shao-Hsien Liu, Sharina D. Person, and Nancy Byatt

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Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors, Ashley N. Matthew, Jacqueto Zephyr, Nageswara Rao Desaboini, Mina Henes, Wasih Kamran, Klajdi Kosovrasti, Adam Hedger, Gordon J. Lockbaum, Jennifer Timm, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation, Asia N. Matthew-Onabanjo, Jenny Janusis, Jose Mercado-Matos, Anne E. Carlisle, Dohoon Kim, Fayola Levine, Peter Cruz-Gordillo, Ryan Richards, Michael J. Lee, and Leslie M. Shaw (Cancer research, 2020-01-15)

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Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis, Zachary J. Milstone, Sherin Saheera, Lauren Bourke, Tomer Shpilka, Cole M. Haynes, and Chinmay M. Trivedi

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A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature, Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer

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A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature [preprint], Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer

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A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods, Jill E. Moore, Henry E. Pratt, Michael J. Purcaro, and Zhiping Weng

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Teamwork for smoking cessation: which smoker was willing to engage their partner? Results from a cross-sectional study, Catherine S. Nagawa, Oluwabunmi M. Emidio, Kate L. Lapane, Thomas K. Houston, Bruce A. Barton, Jamie Faro, Amanda C. Blok, Elizabeth Aaker Orvek, Sarah L. Cutrona, Bridget M. Smith, Jeroan J. Allison, and Rajani S. Sadasivam

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Opioid initiation and injection transition in rural northern New England: A mixed-methods approach, Kerry Nolte, Aurora L. Drew, Peter D. Friedmann, Eric Romo, Linda M. Kinney, and Thomas J. Stopka

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Proteomic and Transcriptional Profiles of Human Stem Cell-Derived beta Cells Following Enteroviral Challenge, Julius O. Nyalwidhe, Agata Jurczyk, Basanthi Satish, Sambra D. Redick, Natasha Qaisar, Melanie I. Trombly, Pranitha Vangala, Riccardo Racicot, Rita Bortell, David M. Harlan, Dale L. Greiner, Michael A. Brehm, Jerry L. Nadler, and Jennifer P. Wang

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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5alpha-dependent manner, Molly Ohainle, Kyusik Kim, Sevnur Komurlu Keceli, Abby Felton, Ed Campbell, Jeremy Luban, and Michael Emerman

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Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans, Deniz M. Ozata, Tianxiong Yu, Haiwei Mou, Ildar Gainetdinov, Cansu Colpan, Katharine Cecchini, Yasin Kaymaz, Pei-Hsuan Wu, Kaili Fan, Alper Kucukural, Zhiping Weng, and Phillip D. Zamore

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Adaptive Evolution Targets a piRNA Precursor Transcription Network, Swapnil Parhad, Tianxiong Yu, Gen Zhang, Nicholas P. Rice, Zhiping Weng, and William E. Theurkauf

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The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility, Pei-Hsuan Wu, Yu Fu, Katharine Cecchini, Deniz M. Ozata, Amena Arif, Tianxiong Yu, Cansu Colpan, Ildar Gainetdinov, Zhiping Weng, and Phillip D. Zamore

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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice [preprint], Pengpeng Liu, Shun-Qing Liang, Chunwei Zheng, Esther Mintzer, Yan G. Zhao, Karthikeyan Ponnienselvan, Aamir Mir, Erik J. Sontheimer, Guangping Gao, Terence R. Flotte, Scot A. Wolfe, and Wen Xue

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Machine Learning Model Based on Transthoracic Bioimpedance and Heart Rate Variability for Lung Fluid Accumulation Detection: Prospective Clinical Study, Natasa Reljin, Hugo F. Posada-Quintero, Caitlin Eaton-Robb, Sophia Binici, Emily Ensom, Eric Y. Ding, Anna Hayes, Jarno Riistama, Chad E. Darling, David D. McManus, and Ki H. Chon

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Drug antagonism and single-agent dominance result from differences in death kinetics, Ryan Richards, Hannah R. Schwartz, Megan E. Honeywell, Mariah S. Stewart, Peter Cruz-Gordillo, Anna J. Joyce, Benjamin D. Landry, and Michael J. Lee

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An atlas of cell types in the mammalian epididymis and vas deferens [preprint], Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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An atlas of cell types in the mouse epididymis and vas deferens, Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans, Raziel Rojas-Rodriguez, Rachel Ziegler, Tiffany DeSouza, Sana Majid, Aylin S. Madore, Nili S. Amir, Veronica A. Pace, Daniel Nachreiner, David Alfego, Jomol Mathew, Katherine Leung, Tiffany Moore Simas, and Silvia Corvera

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Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host, Brittany Rosener, Serkan Sayin, Peter O. Oluoch, Aurian Garcia-Gonzalez, Hirotada Mori, Albertha J. M. Walhout, and Amir Mitchell

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Are dietary fish oil supplements appropriate for dyslipidemia management? A review of the evidence, Samuel C. R. Sherratt, Michael Lero, and R. Preston Mason

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YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte-like cells, Jordan L. Smith, Tomas Rodriguez, Haiwei Mou, Suet-Yan Kwan, Henry E. Pratt, Xiao-Ou Zhang, Yueying Cao, Shun-Qing Liang, Deniz M. Ozata, Tianxiong Yu, Qiangzong Yin, Max Hazeltine, Zhiping Weng, Erik J. Sontheimer, and Wen Xue

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Healthy Eating and Physical Activity Policy, Systems, and Environmental Strategies: A Content Analysis of Community Health Improvement Plans, Meera Sreedhara, Melissa Goulding, Karin V. Goins, Christine F. Frisard, and Stephenie C. Lemon

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Termi-Luc: a versatile assay to monitor full-protein release from ribosomes, Denis Susorov, Shawn B. Egri, and Andrei A. Korostelev

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A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response, Rujapak Sutiwisesak, Nathan D. Hicks, Shayla Boyce, Kenan C. Murphy, Kadamba Papavinasasundaram, Stephen M. Carpenter, Julie Boucau, Neelambari Joshi, Sylvie Le Gall, Sarah M. Fortune, Christopher M. Sassetti, and Samuel M. Behar

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Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir, Jennifer Timm, Klajdi Kosovrasti, Mina Henes, Florian Leidner, Shurong Hou, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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CRISPR-enhanced human adipocyte 'browning' as cell therapy for metabolic disease [preprint], Emmanouela Tsagkaraki, Sarah M. Nicoloro, Tiffany DeSouza, Javier Solivan-Rivera, Anand Desai, Yuefei Shen, Mark Kelly, Adilson L. Guilherme, Felipe Henriques, Raed Ibraheim, Nadia Amrani, Kevin Luk, Stacy Maitland, Randall H. Friedline, Lauren Tauer, Xiaodi Hu, Jason K. Kim, Scot A. Wolfe, Erik J. Sontheimer, Silvia Corvera, and Michael P. Czech

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A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus [preprint], Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G. Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, and Kensuke Futai

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Specific Neuroligin3-alphaNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus, Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G. Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, and Kensuke Futai

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Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus, Motokazu Uchigashima, Ming Leung, Takuya Watanabe, Amy Cheung, Timmy Le, Sabine Pallat, Alexandre Luis Marques Dinis, Masahiko Watanabe, Yuka Imamura Kawasawa, and Kensuke Futai

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Continuous and non-invasive thermography of mouse skin accurately describes core body temperature patterns, but not absolute core temperature, Vincent van der Vinne, Carina A. Pothecary, Sian L. Wilcox, Laura E. McKillop, Lindsay A. Benson, Jenya Kolpakova, Shu K. E. Tam, Lukas B. Krone, Angus S. Fisk, Tatiana S. Wilson, Tomoko Yamagata, James Cantley, Vladyslav V. Vyazovskiy, and Stuart N. Peirson

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High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection, Pranitha Vangala, Rachel Murphy, Sofia A. Quinodoz, Kyle J. Gellatly, Patrick E. McDonel, Mitchell Guttman, and Manuel Garber

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ZNF410 represses fetal globin by devoted control of CHD4/NuRD [preprint], Divya S. Vinjamur, Qiuming Yao, Mitchel A. Cole, Connor McGuckin, Chunyan Ren, Jing Zeng, Mir Hossain, Kevin Luk, Scot A. Wolfe, Luca Pinello, and Daniel E. Bauer

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WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization [preprint], Melissa D. Walker, Gabrielle E. Giese, Amy D. Holdorf, Sushila Bhattacharya, Cedric Diot, Aurian Garcia-Gonzalez, Brent Horowitz, Yong-Uk Lee, Thomas Leland, Xuhang Li, Zeynep Mirza, Huimin Na, Shivani Nanda, Olga Ponomarova, Hefei Zhang, Jingyan Zhang, L. Safak Yilmaz, and Albertha J. M. Walhout

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HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells, Yetao Wang, Lawrence M. Lifshitz, Kyle Gellatly, Sean M. McCauley, Pranitha Vangala, Kyusik Kim, Alan G. Derr, Smita Jaiswal, Alper Kucukural, Patrick McDonel, Thomas C. Greenough, JeanMarie Houghton, Manuel Garber, and Jeremy Luban

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Flexible motor sequence generation during stereotyped escape responses, Yuan Wang, Xiaoqian Zhang, Qi Xin, Wesley Hung, Jeremy Florman, Jing Huo, Tianqi Xu, Yu Xie, Mark J. Alkema, Mei Zhen, and Quan Wen

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Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques, Caylin G. Winchell, Bibhuti B. Mishra, Jia Yao Phuah, Samantha J. Nelson, Christopher M. Sassetti, and JoAnne L. Flynn

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TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2), Brian M. Woolums, Kendra Takle, and Yang Xiang

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Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels, L. Safak Yilmaz, Xuhang Li, Shivani Nanda, Bennett Fox, Frank Schroeder, and Albertha J. M. Walhout

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Depression symptoms and cognitive impairment in older nursing home residents in the USA: A latent class analysis, Yiyang Yuan, Hye Sung Min, Kate L. Lapane, Anthony J. Rothschild, and Christine M. Ulbricht

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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant, Leonid Yurkovetskiy, Thomas Nyalile, Yetao Wang, William E. Diehl, Ann Dauphin, Claudia Carbone, Kristen Veinotte, Shawn B Egri, James B. Munro, Pardis C. Sabeti, Christos A. Kyratsous, Natalya V. Dudkina, Kuang Shen, and Jeremy Luban

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SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain [preprint], Leonid Yurkovetskiy, Thomas Nyalile, Yetao Wang, William E. Diehl, Ann Dauphin, Claudia Carbone, Kristen Veinotte, Shawn B. Egri, Pardis C. Sabeti, Christos Kyratsous, James B. Munro, Kuang Shen, and Jeremy Luban

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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues, Carly G. K. Ziegler, Yuming Cao, Zhiru Guo, Jennifer P. Wang, Robert W. Finberg, Manuel Garber, Alex K. Shalek, Jose Ordovas-Montanes, and HCA Lung Biological Network

Publications from 2019

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A chromosome folding intermediate at the condensin-to-cohesin transition during telophase, Kristin Abramo, Anne-Laure Valton, Sergey V. Venev, Hakan Ozadam, A. Nicole Fox, and Job Dekker (Nature cell biology, 2019-11-01)