Since the school's inception in 1979, students in the Morningside Graduate School of Biomedical Sciences at UMass Chan Medical School have contributed thousands of research publications to the field of biomedical sciences. This collection makes this body of work accessible to our students, faculty, potential recruits, the citizens of Massachusetts, and the world.

This collection is currently closed to new submissions in preparation for moving to a new website platform. New submissions will be reopened when the new platform launches in mid-late August 2022. Keep an eye on the eScholarship home page for updates.

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Publications from 2021

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Social support and strain and emotional distress among Latinos in the northeastern United States, Shir Lerman Ginzburg, Stephenie C. Lemon, Eric Romo, and Milagros C. Rosal

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A phase transition enhances the catalytic activity of SARM1, an NAD(+) glycohydrolase involved in neurodegeneration, Heather S. Loring, Victoria L. Czech, Janneke D. Icso, Lauren C. O'Connor, Sangram Parelkar, Alexandra B. Byrne, and Paul R. Thompson

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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection, Yu-Jung Lu, Palmira Barreira-Silva, Shayla Boyce, Jennifer Powers, Kelly Cavallo, and Samuel M. Behar

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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection [preprint], Yu-Jung Lu, Palmira Barreira-Silva, Shayla Boyce, Jennifer Powers, Kelly Cavallo, and Samuel M. Behar

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Geographic Variation of Statin Use Among US Nursing Home Residents With Life-limiting Illness, Deborah Mack, Jonggyu Baek, Jennifer Tjia, and Kate L. Lapane

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National Trends in Statin Use among the United States Nursing Home Population (2011-2016), Deborah Mack, Anne L. Hume, Jennifer Tjia, and Kate L. Lapane

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Cues from mRNA splicing prevent default Argonaute silencing in C. elegans, Yekaterina V. Makeyeva, Masaki Shirayama, and Craig C. Mello

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Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae, Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard E. Baker, and Allan Jacobson

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Impact of the COVID-19 pandemic on mental health, access to care, and health disparities in the perinatal period, Grace A. Masters, Eugenia Asipenko, Aaron Bergman, Aaron L. Bergman, Sharina D. Person, Linda Brenckle, Tiffany Moore Simas, Jean Y. Ko, Cheryl L. Robbins, and Nancy Byatt

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Development of the Practice Readiness to Evaluate and address Perinatal Depression (PREPD) assessment, Grace A. Masters, Linda Brenckle, Padma Sankaran, Tiffany Moore Simas, Sharina D. Person, Jeroan J. Allison, Douglas Ziedonis, Jean Ko, Cheryl Robbins, and Nancy Byatt

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Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond, Ashley N. Matthew, Florian Leidner, Gordon J. Lockbaum, Mina Henes, Jacqueto Zephyr, Shurong Hou, Nageswara Rao Desaboini, Jennifer Timm, Linah N. Rusere, Debra A. Ragland, Janet L. Paulsen, Kristina L. Prachanronarong, Djade I. Soumana, Ellen A. Nalivaika, Nese Kurt Yilmaz, Akbar Ali, and Celia A. Schiffer

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Prevalence and treatment of neuropathic pain diagnoses among U.S. nursing home residents, Attah Mbrah, Anthony P. Nunes, Anne L. Hume, Danni Zhao, William M. Jesdale, Carol A. Bova, and Kate L. Lapane

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Complex Patients Have More Emergency Visits: Don't Punish the Systems That Serve Them, Eric O. Mick, Matthew J. Alcusky, Nien-Chen Li, Frances E. Eanet, Jeroan J. Allison, Catarina I. Kiefe, and Arlene S. Ash

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Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System [preprint], Michael P. Moazami, Julia M. Rembetsy-Brown, Feng Wang, Pranathi Meda Krishnamurthy, Alexandra Weiss, Miklos G. Marosfoi, Robert M. King, Mona Motwani, Heather L. Gray-Edwards, Katherine A. Fitzgerald, Robert H. Brown Jr., and Jonathan K. Watts

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Integration of high-resolution promoter profiling assays reveals novel, cell type-specific transcription start sites across 115 human cell and tissue types, Jill E. Moore, Xiao-Ou Zhang, Shaimae I. Elhajjajy, Kaili Fan, Henry E. Pratt, Fairlie Reese, Ali Mortazavi, and Zhiping Weng

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Association of killer cell immunoglobulin-like receptors with endemic Burkitt lymphoma in Kenyan children, Beatrice M. Muriuki, Catherine Forconi, Peter O. Oluoch, Jeffrey A. Bailey, Anita Ghansah, Ann M. Moormann, and John M. Ong'echa

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Written Advice Given by African American Smokers to Their Peers: Qualitative Study of Motivational Messages, Catherine S. Nagawa, Jamie M. Faro, Anitha J. Menon, Mayuko Ito Fukunaga, Jessica H. Williams, Dalton Mourao, Oluwabunmi M. Emidio, Maryann Davis, Lori Pbert, Sarah L. Cutrona, Thomas K. Houston, and Rajani S. Sadasivam

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Herbal or Dietary Supplement Use and Hypertensive Medications: Does the Combination Relate to Medication Adherence and Blood Pressure Control, Catherine S. Nagawa, Jessica A. Palakshappa, Rajani S. Sadasivam, and Thomas K. Houston

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Emerging Immunotherapies in the Treatment of Brain Metastases, Edwin Nieblas-Bedolla, Naema Nayyar, Mohini Singh, Ryan J. Sullivan, and Priscilla K. Brastianos

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Hinfp is a guardian of the somatic genome by repressing transposable elements, Niraj K. Nirala, Qi Li, Prachi N. Ghule, Hsi-Ju Chen, Rui Li, Lihua Julie Zhu, Ruijia Wang, Nicholas P. Rice, Junhao Mao, Janet L. Stein, Gary S. Stein, Andre J. van Wijnen, and Y. Tony Ip

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Multiple imputation to quantify misclassification in observational studies of the cognitively impaired: an application for pain assessment in nursing home residents, Anthony P. Nunes, Danni Zhao, William M. Jesdale, and Kate L. Lapane

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NExUS-Heart: Novel examinations using smart technologies for heart health-Data sharing from commercial wearable devices and telehealth engagement in participants with or at risk of atrial fibrillation, Sri Nuvvula, Eric Y. Ding, Connor Saleeba, Qiming Shi, Zi-Yue Wang, Alok Kapoor, Jane S. Saczynski, Steven A. Lubitz, Lara C. Kovell, M. Diane McKee, and David D. McManus

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Androgen Activity Is Associated With PD-L1 Downregulation in Thyroid Cancer, Timmy J. O'Connell, Sina Dadafarin, Melanie Jones, Tomás Rodríguez, Anvita Gupta, Edward Shin, Augustine Moscatello, Codrin Iacob, Humayun Islam, Raj K. Tiwari, and Jan Geliebter

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Allele-specific knockdown of mutant HTT protein via editing at coding region SNP heterozygosities, Sarah Oikemus, Edith L. Pfister, Ellen Sapp, Kathryn O. Chase, Lori A. Kennington, Edward Hudgens, Rachael Miller, Lihua Julie Zhu, Akanksh Chaudhary, Eric O. Mick, Miguel Sena-Esteves, Scot A. Wolfe, Marian DiFiglia, Neil Aronin, and Michael H. Brodsky

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The testis-specific transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in placental mammals [preprint], Deniz M. Ozata, Tianxiong Yu, Katharine Cecchini, Haiwei Mou, Amena Arif, Cansu Colpan, Adriano Biasini, Ildar Gaitendinov, Dirk G. de Rooij, Zhiping Weng, and Phillip D. Zamore

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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice, Pengpeng Liu, Shun-Qing Liang, Chunwei Zheng, Esther Mintzer, Yan G. Zhao, Karthikeyan Ponnienselvan, Aamir Mir, Erik J. Sontheimer, Guangping Gao, Terence R. Flotte, Scot A. Wolfe, and Wen Xue

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Factorbook: an Updated Catalog of Transcription Factor Motifs and Candidate Regulatory Motif Sites [preprint], Henry E. Pratt, Gregory Andrews, Nishigandha Phalke, Michael J. Purcaro, Arjan van der Velde, Jill E. Moore, and Zhiping Weng

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Type I IFN-Driven Immune Cell Dysregulation in Rat Autoimmune Diabetes, Natasha Qaisar, Adediwura Arowosegbe, Alan G. Derr, Alper Kucukural, Basanthi Satish, Riccardo Racicot, Zhiru Guo, Melanie I. Trombly, and Jennifer P. Wang

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A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior, Shankar Ramachandran, Navonil Banerjee, Raja Bhattacharya, Michele L. Lemons, Jeremy Florman, Christopher M. Lambert, Denis Touroutine, Kellianne Alexander, Liliane Schoofs, Mark J. Alkema, Isabel Beets, and Michael M. Francis

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Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia, Monica Reis, Gareth R. Willis, Angeles Fernandez-Gonzalez, Vincent Yeung, Elizabeth Taglauer, Margaret Magaletta, Teagan J. Parsons, Alan G. Derr, Xianlan Liu, Rene Maehr, Stella Kourembanas, and S. Alex Mitsialis

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FLICK: an optimized plate reader-based assay to infer cell death kinetics, Ryan Richards, Megan E. Honeywell, and Michael J. Lee

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Multi-tissue integrative analysis of personal epigenomes [preprint], Joel Rozowsky, Jill E. Moore, Henry E. Pratt, Zhiping Weng, and Mark Gerstein

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Analysis of Emerging Variants in Structured Regions of the SARS-CoV-2 Genome, Sean P. Ryder, Brittany R. Morgan, Peren Coskun, Katianna Antkowiak, and Francesca Massi

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Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample, Divya Shridharmurthy, Danni Zhao, Kate L. Lapane, Jonggyu Baek, Jonathan Kay, and Shao-Hsien Liu

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Lessons from a local effort to screen for SARS-CoV-2, Noah J. Silverstein and Jeremy Luban

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Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection [preprint], Noah J. Silverstein, Yetao Wang, Zachary Manickas-Hill, Claudia C. Carbone, Ann Dauphin, MGH COVID-19 Collection & Processing Team, Jonathan Z. Li, Bruce D. Walker, Xu G. Yu, and Jeremy Luban

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c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease [preprint], Abigail O. Smith, Julie A. Jonassen, Kenley Preval, Roger J. Davis, and Gregory J. Pazour

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Cell-type specific circadian bioluminescence rhythms recorded from Dbp reporter mice reveal circadian oscillator misalignment [preprint], Ciearra B. Smith, Vincent van der Vinne, Eleanor McCartney, Adam C. Stowie, Tanya L. Leise, Blanca Martin-Burgos, Penny C. C. Molyneux, Lauren A. Garbutt, Michael H. Brodsky, Alec J. Davidson, Mary E. Harrington, Robert Dallmann, and David R. Weaver

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Sirtuin 3 Downregulation in Mycobacterium tuberculosis-Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death, Lorissa J. Smulan, Nuria M. Martinez, Michael C. Kiritsy, Chido L. Kativhu, Kelly Cavallo, Christopher M. Sassetti, Amit Singhal, Heinz G. Remold, and Hardy Kornfeld

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Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse beta-Cells, Jarin T. Snyder, Christine Darko, Rohit B. Sharma, and Laura C. Alonso

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Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host-pathogen dynamics in lymphoblastoid cell lines, Elliott D. SoRelle, Joanne Dai, Emmanuela N. Bonglack, Emma M. Heckenberg, Jeffrey Y. Zhou, Stephanie N. Giamberardino, Jeffrey A. Bailey, Simon G. Gregory, Cliburn Chan, and Micah A. Luftig

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Yeast Particle Encapsulation of Scaffolded Terpene Compounds for Controlled Terpene Release, Ernesto R. Soto, Florentina Rus, Hanchen Li, Carli Garceau, Jeffrey Chicca, Elfawal A. Mostafa, David Gazzola, Martin K. Nielsen, Joseph F. Urban Jr., Raffi V. Aroian, and Gary R. Ostroff

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Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles [preprint], Charles A. Specht, E. Jane Homan, Chrono K. Lee, Zhongming Mou, Christina L. Gomez, Maureen M. Hester, Ambily Abraham, Florentina Rus, Gary R. Ostroff, and Stuart M. Levitz

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Nox4 mediates skeletal muscle metabolic responses to exercise, Kalyn S. Specht, Shashi Kant, Heather Learnard, Maura Campbell, Amada D. Caliz, Yongmei Pei, Michaella M. Reif, John F. Keaney Jr., and Siobhan M. Craige

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Methodological Challenges for Epidemiologic Studies of Deprescribing at the End of Life, Jennifer Tjia, Jennifer L. Lund, Deborah Mack, Attah Mbrah, Yiyang Yuan, Qiaoxi Chen, Seun Osundolire, and Cara L. McDermott

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Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide, Helene Tran, Michael P. Moazami, Huiya Yang, Diane Mckenna-Yasek, Catherine Douthwright, Courtney Pinto, Jake P. Metterville, Minwook Shin, Nitasha Sanil, Craig Dooley, Ajit S. Puri, Alexandra Weiss, Nicholas Wightman, Heather L. Gray-Edwards, Miklos G. Marosfoi, Robert M. King, Jonathan K. Watts, and Robert H. Brown Jr.

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Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction, Motokazu Uchigashima, Amy Cheung, and Kensuke Futai

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Annotation of chromatin states in 66 complete mouse epigenomes during development, Arjan van der Velde, Kaili Fan, Junko Tsuji, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, and Zhiping Weng

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Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma [preprint], Marc A. Vittoria, Nathan Kingston, Eric Xia, Rui Hong, Lee Huang, Shayna McDonald, Andrew Tilston- Lunel, Revati A. Darp, Joshua Campbell, Deborah Lang, Xiaowei Xu, Craig J. Ceol, Xaralabos Varelas, and Neil J. Ganem

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WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization, Melissa D. Walker, Gabrielle E. Giese, Amy D. Holdorf, Sushila Bhattacharya, Cedric Diot, Aurian Garcia-Gonzalez, Brent Horowitz, Yong-Uk Lee, Thomas Leland, Xuhang Li, Zeynep Mirza, Huimin Na, Shivani Nanda, Olga Ponomarova, Hefei Zhang, Jingyan Zhang, L. Safak Yilmaz, and Albertha J. M. Walhout

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Development and Validation of an Automated Algorithm to Detect Atrial Fibrillation Within Stored Intensive Care Unit Continuous Electrocardiographic Data: Observational Study, Allan J. Walkey, Syed K. Bashar, Md Billal. Hossain, Eric Y. Ding, Daniella Albuquerque, Michael Winter, Ki H. Chon, and David D. McManus

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Aging and COVID-19 in Minority Populations: a Perfect Storm, Tubanji Walubita, Ariel Beccia, Esther Boama-Nyarko, Melissa Goulding, Carly Herbert, Jessica Kloppenburg, Guadalupe Mabry, Grace A. Masters, Asli McCullers, and Sarah N. Forrester

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Deficient spermiogenesis in mice lacking Rlim, Feng Wang, Maria Gracia Gervasi, Ana Boskovic, Fengyun Sun, Vera D. Rinaldi, Jun Yu, Mary C. Wallingford, Darya A. Tourzani, Jesse Mager, Lihua Julie Zhu, Oliver J. Rando, Pablo E. Visconti, Lara Strittmatter, and Ingolf Bach

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Role of epigenetics in unicellular to multicellular transition in Dictyostelium, Simon Yuan Wang, Elizabeth Ann Pollina, I-Hao Wang, Lindsay Kristina Pino, Henry L. Bushnell, Ken Takashima, Colette Fritsche, George Sabin, Benjamin Aaron. Garcia, Paul L. Greer, and Eric Lieberman Greer

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Clarification of human blood ILC subtype interrelatedness and discovery of amphiregulin production by human NK cells shed light on HIV-1 pathogenesis [preprint], Yetao Wang, Lawrence M. Lifshitz, Noah J. Silverstein, Esther Mintzer, Kevin Luk, Pamela St. Louis, Michael A. Brehm, Scot A. Wolfe, Steven G. Deeks, and Jeremy Luban

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NHR-49/PPAR-alpha and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase, Khursheed A. Wani, Debanjan Goswamy, Stefan Taubert, Ramesh Ratnappan, Arjumand Ghazi, and Javier E. Irazoqui

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The Intestinal and Oral Microbiomes Are Robust Predictors of COVID-19 Severity the Main Predictor of COVID-19-related Fatality [preprint], Doyle V. Ward, Shakti Bhattarai, Mayra Rojas-Correa, Ayan Purkayastha, Devon Holler, Ming Da Qu, William G. Mitchell, Jason D. Yang, Samuel Fountain, Abigail Zeamer, Catherine Forconi, Gavin Fujimori, Boaz Odwar, Caitlin Cawley, Beth A. McCormick, Ann M. Moormann, Mireya Wessolossky, Vanni Bucci, and Ana Maldonado-Contreras

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The HIV-1 capsid core is an opportunistic nuclear import receptor [preprint], Guangai Xue, Hyun Jae Yu, University of Massachusetts Medical School, Anna T. Gres, Mehmet Hakan Guney, Stefan G. Sarafianos, Jeremy Luban, and Vineet N. KewalRamani

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Perspectives on barriers and facilitators to mental health support after a traumatic birth among a sample of primarily White and privately insured patients, Wanlu (LuLu) Xu, Esther Boama-Nyarko, Grace A. Masters, Tiffany A. Moore Simas, Christine M. Ulbricht, and Nancy Byatt

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Lung eosinophils elicited during allergic and acute aspergillosis express RORgammat and IL-23R but do not require IL-23 for IL-17 production, Bhawna Yadav, Charles A. Specht, Chrono K. Lee, Maria Pokrovskii, Jun R. Huh, Dan R. Littman, and Stuart M. Levitz

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An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis, Batuhan Yenilmez, Nicole Wetoska, Mark Kelly, Dimas Echeverria, Kyounghee Min, Lawrence M. Lifshitz, Julia F. Alterman, Matthew R. Hassler, Samuel R. Hildebrand, Chloe DiMarzio, Nicholas McHugh, Lorenc Vangjeli, Jacquelyn Sousa, Michael A. Brehm, Anastasia Khvorova, and Michael P. Czech

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Changes in depressive symptoms and cognitive impairment in older long-stay nursing home residents in the USA: a latent transition analysis, Yiyang Yuan, Kate L. Lapane, Anthony J. Rothschild, and Christine M. Ulbricht

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Physical Frailty and Cognitive Impairment in Older Adults in United States Nursing Homes, Yiyang Yuan, Kate L. Lapane, Jennifer Tjia, Jonggyu Baek, Shao-Hsien Liu, and Christine M. Ulbricht

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Physical frailty and cognitive impairment in older nursing home residents: a latent class analysis, Yiyang Yuan, Kate L. Lapane, Jennifer Tjia, Jonggyu Baek, Shao-Hsien Liu, and Christine M. Ulbricht

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Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes, Tianxiong Yu, Kaili Fan, Deniz M. Ozata, Gen Zhang, Yu Fu, William E. Theurkauf, Phillip D. Zamore, and Zhiping Weng

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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis, Matija Zelic, Boyao Zhang, M. Pontus A. Orning, Egil Lien, and Dimitry Ofengeim

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Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance [preprint], Jacqueto Zephyr, Nageswara Rao Desaboini, Sang V. Vo, Mina Henes, Klajdi Kosovrasti, Ashley N. Matthew, Adam K. Hedger, Jennifer Timm, Elise T. Chan, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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piRNA-independent transposon silencing by the Drosophila THO complex, Gen Zhang, Tianxiong Yu, Swapnil Parhad, Samantha Ho, Zhiping Weng, and William E. Theurkauf

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Investigating the Potential Roles of SINEs in the Human Genome, Xiao-Ou Zhang, Henry E. Pratt, and Zhiping Weng

Publications from 2020

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Systematic evaluation of chromosome conformation capture assays [preprint], Betul Akgol-Oksuz, Liyan Yang, Sergey V. Venev, Nils Krietenstein, Krishna M. Parsi, Hakan Ozadam, Marlies E. Oomen, Ankita Nand, Hui Mao, Ryan M.J. Genga, Rene Maehr, Oliver J. Rando, Johan H. Gibcus, and Job Dekker

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The 'Take a Break' game: Randomized trial protocol for a technology-assisted brief abstinence experience designed to engage lower-motivated smokers., Daniel J. Amante, Amanda C. Blok, Catherine S. Nagawa, Jessica G. Wijesundara, Jeroan J. Allison, Sharina D. Person, Jeanne Morley, Joseph Conigliaro, Kristin M. Mattocks, Lawrence D. Garber, Thomas K. Houston, and Rajani S. Sadasivam

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Immunometabolism in Caenorhabditis elegans, Sarah M. Anderson and Read Pukkila-Worley

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Cell cycle-associated expression patterns predict gene function in mycobacteria [preprint], Aditya Bandekar, Sishir Subedi, Thomas Ioerger, and Christopher M. Sassetti

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Associations between perceived everyday discrimination, discrimination attributions, and binge eating among Latinas: results from the National Latino and Asian American Study, Ariel Beccia, William M. Jesdale, and Kate L. Lapane

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The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy, Annabelle Biscans, Jillian Caiazzi, Sarah M. Davis, Nicholas McHugh, Jacquelyn Sousa, and Anastasia Khvorova

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Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase [preprint], Yi Cai, Eleni Jaecklein, Jared Mackenzie, Kadamba Papavinasasundaram, Michigan State University, Xinchun Chen, Africa Health Research Institute, and Christopher M. Sassetti

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mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis, Camila Martinez Calejman, S. Trefely, S. W. Entwisle, Amelia K. Luciano, Su Myung. Jung, Wen-Yu Hsiao, A. Torres, C. M. Hung, H. Li, N. W. Snyder, J. Villen, K. E. Wellen, and David A. Guertin

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Single-cell analysis of upper airway cells reveals host-viral dynamics in influenza infected adults [preprint], Yuming Cao, Zhiru Guo, Pranitha Vangala, Elisa Donnard, Ping Liu, Patrick McDonel, Jose Ordovas Montanes, Alex K. Shalek, Robert W. Finberg, Jennifer P. Wang, and Manuel Garber

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ArfB can displace mRNA to rescue stalled ribosomes, Christine E. Carbone, Gabriel Demo, Rohini Madireddy, Egor Svidritskiy, and Andrei A. Korostelev

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Integrated miRNA-/mRNA-Seq of the Habenulo-Interpeduncular Circuit During Acute Nicotine Withdrawal, Alison P. Casserly, Junko Tsuji, Rubing Zhao-Shea, Ciearra B. Smith, Susanna Molas-Casacuberta, Andrew R. Tapper, Zhiping Weng, and Paul D. Gardner

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Roles of Adipokines in Digestive Diseases: Markers of Inflammation, Metabolic Alteration and Disease Progression, Ming-Ling Chang, Zinger Yang, and Sien-Sing Yang

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Combining Citizen Science and Genomics to Investigate Tick, Pathogen, and Commensal Microbiome at Single-Tick Resolution, Gaurav Chauhan, Jesse McClure, Jessica Hekman, Patrick W. Marsh, Jeffrey A. Bailey, Rachel F. Daniels, Diane P. Genereux, and Elinor K. Karlsson

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The Association Between Patient-reported Clinical Factors and 30-day Acute Care Utilization in Chronic Heart Failure, Jinying Chen, Rajani S. Sadasivam, Amanda C. Blok, Christine S. Ritchie, Catherine S. Nagawa, Elizabeth Aaker Orvek, Kanan Patel, and Thomas K. Houston

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Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation, Jan T. Czerminski and Jeanne B. Lawrence

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Midbrain Dopamine Controls Anxiety-like Behavior by Engaging Unique Interpeduncular Nucleus Microcircuitry, Steven R. DeGroot, Rubing Zhao-Shea, Leeyup Chung, Paul M. Klenowski, Fangmiao Sun, Susanna Molas-Casacuberta, Paul D. Gardner, Yulong Li, and Andrew R. Tapper

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BCL11A enhancer edited hematopoietic stem cells persist in rhesus monkeys without toxicity, Selami Demirci, Jing Zeng, Yuxuan Wu, Naoya Uchida, Anne H. Shen, Danilo Pellin, Jackson Gamer, Morgan Yapundich, Claire Drysdale, Jasmine Bonanno, Aylin C. Bonifacino, Allen Krouse, Nathaniel Seth. Linde, Theresa Engels, Robert E. Donahue, Juan J. Haro-Mora, Alexis Leonard, Tina Nassehi, Kevin Luk, Shaina N. Porter, Cicera R. Lazzarotto, Shengdar Q. Tsai, Mitchell Weiss, Shondra M. Pruett-Miller, Scot A. Wolfe, Daniel E. Bauer, and John F. Tisdale

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CD4 Effectors Need to Recognize Antigen Locally to Become Cytotoxic CD4 and Follicular Helper T Cells [preprint], Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Bianca L. Bautista, Michael C. Jones, Olivia Kugler-Umana, Karen A. Kelly, and Susan L. Swain

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Engineering essential genes with a "jump board" strategy using CRISPR/Cas9, Ye Duan, Sungwook Choi, Charles Nelson, and Victor R. Ambros

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RNA-seq with RNase H-based ribosomal RNA depletion specifically designed for C. elegans, Ye Duan, Yongming Sun, and Victor R. Ambros

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Expanded encyclopaedias of DNA elements in the human and mouse genomes, ENCODE Project Consortium, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, Xiao-Ou Zhang, Shaimae I. Elhajjajy, Jack Huey, Job Dekker, J. Michael Cherry, Richard M. Myers, Bing Ren, Brenton R. Graveley, Mark B. Gerstein, Len A. Pennacchio, Michael P. Snyder, Bradley E. Bernstein, Barbara Wold, Ross C. Hardison, Thomas R. Gingeras, John A. Stamatoyannopoulos, and Zhiping Weng

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In Situ Regulated Dopamine Transporter Trafficking: There's No Place Like Home, Rita R. Fagan, Patrick J. Kearney, and Haley E. Melikian

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Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact, Rita R. Fagan, Patrick Kearney, Carolyn G. Sweeney, Dino Luethi, Florianne E. Schoot Uiterkamp, Klaus Schicker, Brian S. Alejandro, Lauren C. O'Connor, Harald H. Sitte, and Haley Melikian

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Genetic and Epigenetic Features of Promoters with Ubiquitous Chromatin Accessibility Support Ubiquitous Transcription of Cell-essential Genes [preprint], Kaili Fan, Jill E. Moore, Xiao-Ou Zhang, and Zhiping Weng

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Comparison of a Collective Intelligence Tailored Messaging System on Smoking Cessation Between African American and White People Who Smoke: Quasi-Experimental Design, Jamie Faro, Catherine S. Nagawa, Jeroan J. Allison, Stephenie C. Lemon, Kathleen M. Mazor, Thomas K. Houston, and Rajani S. Sadasivam

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The relationship of aging, complete tooth loss, and having a dental visit in the last 12 months, Andriana M. Foiles Sifuentes, Maira Castaneda-Avila, and Kate L. Lapane

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The Role of Limited English Proficiency and Access to Health Insurance and Health Care in the Affordable Care Act Era, Andriana M. Foiles Sifuentes, Monica Robledo Cornejo, Nien-Chen Li, Maira Castaneda-Avila, Jennifer Tjia, and Kate L. Lapane

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Drosophila Cryptochrome: Variations in Blue, Lauren E. Foley and Patrick Emery

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Innate Immunity in the C. elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development, Kyle J. Foster, Hilary K. Cheesman, Pengpeng Liu, Nicholas D. Peterson, Sarah M. Anderson, and Read Pukkila-Worley

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From Tank to Treatment: Modeling Melanoma in Zebrafish, William Tyler Frantz and Craig J. Ceol

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Early life lessons: The lasting effects of germline epigenetic information on organismal development, Carolina Galan, Marina Krykbaeva, and Oliver J. Rando