GSBS Student Publications
Title
mRNA and cytoskeletal filaments
GSBS Program
Biochemistry & Molecular Pharmacology
UMMS Affiliation
Graduate School of Biomedical Sciences
Date
2-1-1997
Document Type
Article
Medical Subject Headings
Biological Transport; Cytoskeleton; Microfilaments; RNA, Messenger
Disciplines
Life Sciences | Medicine and Health Sciences
Abstract
The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1alpha.
Rights and Permissions
Citation: Curr Opin Cell Biol. 1997 Feb;9(1):109-15.
Related Resources
Journal Title
Current opinion in cell biology
PubMed ID
9013679
Repository Citation
Bassell, Gary J. and Singer, Robert H., "mRNA and cytoskeletal filaments" (1997). GSBS Student Publications. 86.
https://escholarship.umassmed.edu/gsbs_sp/86