GSBS Student Publications

Title

mRNA and cytoskeletal filaments

GSBS Program

Biochemistry & Molecular Pharmacology

Publication Date

1997-02-01

UMMS Affiliation

Graduate School of Biomedical Sciences

Document Type

Article

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1alpha.

Source

Curr Opin Cell Biol. 1997 Feb;9(1):109-15.

Journal/Book/Conference Title

Current opinion in cell biology

Related Resources

Link to article in PubMed

PubMed ID

9013679

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