GSBS Student Publications

Title

Common principles in protein folding and antigen presentation

GSBS Program

Biochemistry & Molecular Pharmacology

Publication Date

1991-07-01

UMMS Affiliation

Graduate School of Biomedical Sciences; Department of Pharmacology

Document Type

Article

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

The regular recurrence of hydrophobic amino acid residues along a peptide sequence determines the formation of a longitudinal hydrophobic strip when the peptide forms an alpha-helix. An understanding of the ways this may affect both folding of nascent proteins and antigen presentation should facilitate vaccine and therapeutics design.

Source

Trends Biotechnol. 1991 Jul;9(7):238-42.

Journal/Book/Conference Title

Trends in biotechnology

Related Resources

Link to article in PubMed

PubMed ID

1370048

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