Common principles in protein folding and antigen presentation
Biochemistry & Molecular Pharmacology
Graduate School of Biomedical Sciences; Department of Pharmacology
Life Sciences | Medicine and Health Sciences
The regular recurrence of hydrophobic amino acid residues along a peptide sequence determines the formation of a longitudinal hydrophobic strip when the peptide forms an alpha-helix. An understanding of the ways this may affect both folding of nascent proteins and antigen presentation should facilitate vaccine and therapeutics design.
Trends Biotechnol. 1991 Jul;9(7):238-42.
Trends in biotechnology
Lu S, Reyes VE, Torgerson RR, Lew RA, Humphreys RE. (1991). Common principles in protein folding and antigen presentation. GSBS Student Publications. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/788