GSBS Student Publications

Title

Ribo-gnome: the big world of small RNAs

Publication Date

2005-09-06

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology; Graduate School of Biomedical Sciences

Document Type

Article

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

Small RNA guides--microRNAs, small interfering RNAs, and repeat-associated small interfering RNAs, 21 to 30 nucleotides in length--shape diverse cellular pathways, from chromosome architecture to stem cell maintenance. Fifteen years after the discovery of RNA silencing, we are only just beginning to understand the depth and complexity of how these RNAs regulate gene expression and to consider their role in shaping the evolutionary history of higher eukaryotes.

DOI of Published Version

10.1126/science.1111444

Source

Science. 2005 Sep 2;309(5740):1519-24. Link to article on publisher's site

Journal/Book/Conference Title

Science (New York, N.Y.)

Related Resources

Link to Article in PubMed

PubMed ID

16141061

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