GSBS Student Publications

Title

Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4

Publication Date

2003-10-01

UMMS Affiliation

Graduate School of Biomedical Sciences; Department of Biochemistry and Molecular Pharmacology

Document Type

Article

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

We report the expression of zebrafish lmo4 during the first 48 h of development. Like its murine ortholog, lmo4 is expressed in somitic mesoderm, branchial arches, otic vesicles, and limb (pectoral fin) buds. In addition, however, we report zebrafish lmo4 expression in the developing eye, cardiovascular tissue, and the neural plate and telencephalon. We demonstrate that expression in the rostral hindbrain requires acerebellar (ace/fgf8) and spiel ohne grenzen (spg/pou2) activity.

Source

Mech Dev. 2002 Dec;119 Suppl 1:S185-9.

Journal/Book/Conference Title

Mechanisms of development

Related Resources

Link to article in PubMed

PubMed ID

14516683

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