GSBS Student Publications
Title
Eaten to death
GSBS Program
Interdisciplinary Graduate Program
Publication Date
2014-12-01
UMMS Affiliation
Department of Cancer Biology
Document Type
Article
Disciplines
Cell Biology | Cellular and Molecular Physiology
Abstract
Macro-autophagy (hereafter referred to as autophagy) delivers cytoplasmic material to the lysosome for degradation, and has been implicated in many cellular processes, including stress, infection, survival and death. Although the regulation and role of autophagy in stress, infection and survival is apparent, its involvement during cell death remains relatively unclear. In this review, we highlight what is known about the role that autophagy can play during physiological cell death, and discuss the implications of better understanding cellular destruction that involves autophagy.
Keywords
ATG genes, apoptosis, autophagy, cell death, necrosis
DOI of Published Version
10.1111/febs.13114
Source
FEBS J. 2014 Dec;281(24):5411-7. doi: 10.1111/febs.13114. Epub 2014 Nov 10. Link to article on publisher's site
Journal/Book/Conference Title
The FEBS journal
Related Resources
PubMed ID
25323556
Repository Citation
Nelson C, Baehrecke EH. (2014). Eaten to death. GSBS Student Publications. https://doi.org/10.1111/febs.13114. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/2050