GSBS Student Publications
Title
Eaten to death
GSBS Program
Interdisciplinary Graduate Program
UMMS Affiliation
Department of Cancer Biology
Date
12-1-2014
Document Type
Article
Disciplines
Cell Biology | Cellular and Molecular Physiology
Abstract
Macro-autophagy (hereafter referred to as autophagy) delivers cytoplasmic material to the lysosome for degradation, and has been implicated in many cellular processes, including stress, infection, survival and death. Although the regulation and role of autophagy in stress, infection and survival is apparent, its involvement during cell death remains relatively unclear. In this review, we highlight what is known about the role that autophagy can play during physiological cell death, and discuss the implications of better understanding cellular destruction that involves autophagy.
DOI of Published Version
10.1111/febs.13114
Source
FEBS J. 2014 Dec;281(24):5411-7. doi: 10.1111/febs.13114. Epub 2014 Nov 10. Link to article on publisher's site
Related Resources
Keywords
ATG genes, apoptosis, autophagy, cell death, necrosis
Journal Title
The FEBS journal
PubMed ID
25323556
Repository Citation
Nelson, Charles and Baehrecke, Eric H., "Eaten to death" (2014). GSBS Student Publications. 2050.
https://escholarship.umassmed.edu/gsbs_sp/2050