GSBS Student Publications

Student Author(s)

Yuxin Chen

GSBS Program

Immunology & Microbiology

Publication Date


UMMS Affiliation

Department of Medicine

Document Type



Immunology and Infectious Disease | Immunoprophylaxis and Therapy


DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development.


AIDS, DNA immunization, HIV-1, vaccine

Rights and Permissions

© 2014 by the authors; licensee MDPI, Basel, Switzerland.

DOI of Published Version



Vaccines (Basel). 2014 Feb 25;2(1):138-59. doi: 10.3390/vaccines2010138. Link to article on publisher's site

Journal/Book/Conference Title


Related Resources

Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution 3.0 License
This work is licensed under a Creative Commons Attribution 3.0 License.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.