Academic Program
Immunology & Microbiology
UMMS Affiliation
Department of Medicine
Publication Date
2014-02-25
Document Type
Article
Disciplines
Immunology and Infectious Disease | Immunoprophylaxis and Therapy
Abstract
DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development.
Keywords
AIDS, DNA immunization, HIV-1, vaccine
Rights and Permissions
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
DOI of Published Version
10.3390/vaccines2010138
Source
Vaccines (Basel). 2014 Feb 25;2(1):138-59. doi: 10.3390/vaccines2010138. Link to article on publisher's site
Journal/Book/Conference Title
Vaccines
Related Resources
PubMed ID
26344472
Repository Citation
Chen Y, Wang S, Lu S. (2014). DNA Immunization for HIV Vaccine Development. GSBS Student Publications. https://doi.org/10.3390/vaccines2010138. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/2017