Department of Medicine
Immunology and Infectious Disease | Immunoprophylaxis and Therapy
DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development.
AIDS, DNA immunization, HIV-1, vaccine
Rights and Permissions
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
DOI of Published Version
Vaccines (Basel). 2014 Feb 25;2(1):138-59. doi: 10.3390/vaccines2010138. Link to article on publisher's site
Chen Y, Wang S, Lu S. (2014). DNA Immunization for HIV Vaccine Development. Morningside Graduate School of Biomedical Sciences Student Publications. https://doi.org/10.3390/vaccines2010138. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/2017