Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): Design and Rationale
Authors
Waring, Molly E.McManus, Richard H.
Saczynski, Jane S.
Anatchkova, Milena D.
McManus, David D.
Devereaux, Randolph
Goldberg, Robert J.
Allison, Jeroan J.
Kiefe, Catarina I.
Student Authors
Richard H. McManusUMass Chan Affiliations
Department of Medicine, Division of Cardiovascular MedicineDepartment of Medicine, Division of Geriatric Medicine
Meyers Primary Care Institute
Department of Quantitative Health Sciences
Document Type
Journal ArticlePublication Date
2012-09-01Keywords
Acute Coronary SyndromeHospitalization
Outcome Assessment (Health Care)
Quality of Life
UMCCTS funding
Cardiovascular Diseases
Health Services Research
Life Sciences
Medicine and Health Sciences
Metadata
Show full item recordAbstract
Background: Cardiovascular disease continues to cause significant morbidity, mortality, and impaired quality of life, with unrealized health gains from the underuse of available evidence. The Transitions, Risks, and Actions in Coronary Events Center for Outcomes Research and Education (TRACE-CORE) aims to advance the science of acute coronary syndromes by examining the determinants and outcomes of the quality of transition from hospital to community and by quantifying the impact of potentially modifiable characteristics associated with decreased quality of life, rehospitalization, and mortality. Methods and Results: TRACE-CORE comprises a longitudinal multiracial cohort of patients hospitalized with acute coronary syndromes, 2 research projects, and development of a nucleus of early stage investigators. We are currently enrolling 2500 adults hospitalized for acute coronary syndromes at 6 hospitals in the northeastern and southeastern United States. We will follow these patients for 24 months after hospitalization through medical record abstraction and 5 patient interviews focusing on quality of life, cardiac events, rehospitalizations, mortality, and medical, behavioral, and psychosocial characteristics. The Transitions Project studies determinants of and disparities in outcomes of the quality of patients' transition from hospital to community. Focusing on potentially modifiable factors, the Action Scores Project will develop and validate action scores to predict recurrent cardiac events, death, and quality of life, describe longitudinal variation in these scores, and develop a dashboard for patient and provider action on the basis of these scores. Conclusions: In TRACE-CORE, sound methodologic principles of observational studies converge with outcomes and effectiveness research approaches. We expect that our data, research infrastructure, and research projects will inform the development of novel secondary prevention approaches and underpin the careers of cardiovascular outcomes researchers.Source
Waring ME, McManus RH, Saczynski JS, Anatchkova MD, McManus DD, Devereaux RS, Goldberg RJ, Allison JJ, Kiefe CI; for the TRACE-CORE Investigators. Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): Design and Rationale. Circ Cardiovasc Qual Outcomes. 2012 Sep 1;5(5):e44-e50. doi:10.1161/CIRCOUTCOMES.112.965418
DOI
10.1161/CIRCOUTCOMES.112.965418Permanent Link to this Item
http://hdl.handle.net/20.500.14038/33263PubMed ID
22991349Related Resources
ae974a485f413a2113503eed53cd6c53
10.1161/CIRCOUTCOMES.112.965418