Title
MicroRNA therapeutics
Academic Program
Neuroscience
UMMS Affiliation
Department of Biochemistry and Molecular Pharmacology
Publication Date
2011-12-01
Document Type
Article
Disciplines
Life Sciences | Medicine and Health Sciences | Neuroscience and Neurobiology
Abstract
MicroRNAs (miRNAs) provide new therapeutic targets for many diseases, while their myriad roles in development and cellular processes make them fascinating to study. We still do not fully understand the molecular mechanisms by which miRNAs regulate gene expression nor do we know the complete repertoire of mRNAs each miRNA regulates. However, recent progress in the development of effective strategies to block miRNAs suggests that anti-miRNA drugs may soon be used in the clinic.
DOI of Published Version
10.1038/gt.2011.50
Source
Gene Ther. 2011 Dec;18(12):1104-10. doi: 10.1038/gt.2011.50. Epub 2011 Apr 28. Link to article on publisher's site
Journal/Book/Conference Title
Gene therapy
Related Resources
PubMed ID
21525952
Repository Citation
Broderick JA, Zamore PD. (2011). MicroRNA therapeutics. GSBS Student Publications. https://doi.org/10.1038/gt.2011.50. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/1738