GSBS Student Publications

Title

The two CRYs of the butterfly

Student Author(s)

Quan Yuan

GSBS Program

Neuroscience

Publication Date

2005-12-08

UMMS Affiliation

Department of Neurobiology; Reppert Lab; Graduate School of Biomedical Sciences, Neuroscience Program

Document Type

Article

Disciplines

Neuroscience and Neurobiology

Abstract

Animal flavoproteins called cryptochromes (CRYs) are generally believed to have distinct circadian clock functions in insects and mammals. We have discovered that the monarch butterfly, Danaus plexippus, has two cry genes: one encodes a fly-like protein with photosensitive properties, while the other encodes a mouse-like protein with potent transcriptional repressive activity. Database searches show that other non-drosophilid insects also have two cry genes. These findings change our view of how some insect clocks may work and redefine the evolution of animal CRYs.

DOI of Published Version

10.1016/j.cub.2005.11.030

Source

Curr Biol. 2005 Dec 6;15(23):R953-4. Link to article on publisher's site

Journal/Book/Conference Title

Current biology : CB

Related Resources

Link to Article in PubMed

PubMed ID

16332522

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