GSBS Student Publications

Title

Hepcidin regulation of iron transport

Publication Date

2008-10-22

UMMS Affiliation

Graduate School of Biomedical Sciences; Department of Exercise and Nutrition Sciences

Document Type

Article

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

The discovery of hepcidin as a key regulator of iron homeostasis has advanced our current knowledge of this field. Liver-derived hepcidin peptide is secreted in response to iron and inflammation and interacts with the iron export protein ferroportin. This review summarizes recent advances discussed at the Symposium. A particular focus is on molecular interactions between hepcidin and ferroportin, the regulation of hepcidin expression by iron and inflammation, and emerging methods to measure serum hepcidin in human populations.

DOI of Published Version

10.3945/jn.108.096347

Source

J Nutr. 2008 Nov;138(11):2284-8. Link to article on publisher's site

Journal/Book/Conference Title

The Journal of nutrition

Related Resources

Link to Article in PubMed

PubMed ID

18936232

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