Title
Finding Plk3
Academic Program
Biochemistry & Molecular Pharmacology
UMMS Affiliation
Graduate School of Biomedical Sciences; Department of Molecular and Cellular Biology
Publication Date
2007-06-15
Document Type
Article
Disciplines
Life Sciences | Medicine and Health Sciences
Abstract
Polo-like kinases (Plks) are a highly conserved family of kinases found in flies, yeast and vertebrates. Plks derive their name from homology to the gene product of polo, a protein kinase first identified in Drosophila. Three polo-like kinases have been identified in vertebrates: Plk1, Plk2 and Plk3. Studies on Plk1 have revealed a great deal of information on its multiple functions, however Plk2 and Plk3 functions have not been fully explored. In this perspective we discuss recent work on Plk3 expression, function and localization in the context of previous reports on Plk3 and in terms of its relationship to Plk1.
DOI of Published Version
10.4161/cc.6.11.4275
Source
Cell Cycle. 2007 Jun 1;6(11):1314-8. Epub 2007 Jun 11.
Journal/Book/Conference Title
Cell cycle (Georgetown, Tex.)
Related Resources
PubMed ID
17568195
Repository Citation
Zimmerman WC, Erikson RL. (2007). Finding Plk3. GSBS Student Publications. https://doi.org/10.4161/cc.6.11.4275. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/1399