GSBS Student Publications
Title
Regulation of histone gene expression
Publication Date
1992-04-01
UMMS Affiliation
Graduate School of Biomedical Sciences; University of Massachusetts Medical Center
Document Type
Article
Disciplines
Life Sciences | Medicine and Health Sciences
Abstract
Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory elements. The three-dimensional organization of the promoter and, in particular, its spatial relationship with the nuclear matrix scaffold, may be important factors of transcription regulation.
Source
Curr Opin Cell Biol. 1992 Apr;4(2):166-73.
Journal/Book/Conference Title
Current opinion in cell biology
Related Resources
PubMed ID
1599687
Repository Citation
Stein, Gary S.; Stein, Janet L.; Van Wijnen, Andre J.; and Lian, Jane B., "Regulation of histone gene expression" (1992). GSBS Student Publications. 1178.
https://escholarship.umassmed.edu/gsbs_sp/1178