Title
Regulation of histone gene expression
Publication Date
1992-04-01
UMMS Affiliation
Graduate School of Biomedical Sciences; University of Massachusetts Medical Center
Document Type
Article
Disciplines
Life Sciences | Medicine and Health Sciences
Abstract
Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory elements. The three-dimensional organization of the promoter and, in particular, its spatial relationship with the nuclear matrix scaffold, may be important factors of transcription regulation.
Source
Curr Opin Cell Biol. 1992 Apr;4(2):166-73.
Journal/Book/Conference Title
Current opinion in cell biology
Related Resources
PubMed ID
1599687
Repository Citation
Stein GS, Stein JL, Van Wijnen AJ, Lian JB. (1992). Regulation of histone gene expression. GSBS Student Publications. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/1178